ISSN:
1432-0878
Schlagwort(e):
Pituicytes
;
Endothelial cells
;
Centrioles
;
Cilia formation
;
Influence of Furosemid (dehydration) and colchicine
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary In adult rats, dehydration produced by the injection of Furosemid (Lasix®) induces the formation of new centrioles in the endothelial cells of the posterior lobe of the hypophysis. Colchicine considerably amplifies this phenomenon and centriologenesis and cilia formation are strikingly apparent in the pituicytes. In control animals, centrioles are quite exceptional in pituicytes and endothelial cells. All steps of the assembly of centrioles from a granular matrix, and the differentiation of atypical (mainly 9+0 and 8+1) cilia are observed in pituicytes. Dehydration increases the mitotic activity of the pituicytes. The respective roles of dehydration, Furosemid and colchicine in the stimulation of centriologenesis are briefly discussed. This work was supported by a grant (1973–1974) from the Belgian National Fund for Scientific Research and by grant no. 1.120 from the Belgian National Fund for Medical Research.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00226769
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