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  • 1
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    Control of self-assembly of DNA tubules through integration of gold nanoparticles (2009)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2009-01-03
    Description: The assembly of nanoparticles into three-dimensional (3D) architectures could allow for greater control of the interactions between these particles or with molecules. DNA tubes are known to form through either self-association of multi-helix DNA bundle structures or closing up of 2D DNA tile lattices. By the attachment of single-stranded DNA to gold nanoparticles, nanotubes of various 3D architectures can form, ranging in shape from stacked rings to single spirals, double spirals, and nested spirals. The nanoparticles are active elements that control the preference for specific tube conformations through size-dependent steric repulsion effects. For example, we can control the tube assembly to favor stacked-ring structures using 10-nanometer gold nanoparticles. Electron tomography revealed a left-handed chirality in the spiral tubes, double-wall tube features, and conformational transitions between tubes.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893555/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893555/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sharma, Jaswinder -- Chhabra, Rahul -- Cheng, Anchi -- Brownell, Jonathan -- Liu, Yan -- Yan, Hao -- P41 RR-01081/RR/NCRR NIH HHS/ -- P41 RR000592/RR/NCRR NIH HHS/ -- P41 RR017573/RR/NCRR NIH HHS/ -- P41 RR017573-086704/RR/NCRR NIH HHS/ -- RR17573/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 2009 Jan 2;323(5910):112-6. doi: 10.1126/science.1165831.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Single Molecule Biophysics, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19119229" target="_blank"〉PubMed〈/a〉
    Keywords: DNA/*chemistry ; Electron Microscope Tomography ; *Gold ; Image Processing, Computer-Assisted ; Inverted Repeat Sequences ; Metal Nanoparticles/*chemistry ; Nanotubes/*chemistry ; Nucleic Acid Conformation ; Thermodynamics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Orientation maps of subjective contours in visual cortex (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-12-20
    Description: Responses to subjective contours in visual cortical areas V1 and V2 in adult cats were investigated by optical imaging of intrinsic signals and single-unit recording. Both V1 and V2 contain maps of the orientation of subjective gratings that have their basis in specific kinds of neuronal responses to subjective orientations. A greater proportion of neurons in V2 than in V1 show a robust response to subjective edges. Through the use of subjective stimuli in which the orientation of the luminance component is invariant, an unmasked V1 response to subjective edges alone can be demonstrated. The data indicate that the processing of subjective contours begins as early as V1 and continues progressively in higher cortical areas.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sheth, B R -- Sharma, J -- Rao, S C -- Sur, M -- EY07023/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1996 Dec 20;274(5295):2110-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. msur@wccf.mit.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8953048" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Brain Mapping ; Cats ; *Form Perception ; Image Processing, Computer-Assisted ; Light ; Neurons/*physiology ; Visual Cortex/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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