Publication Date:
1983-02-25
Description:
There is evidence that the mammalian female genital tract is capable of responding immunologically when challenged with alloantigens. The antigenic properties of male gametes have been well delineated. However, it is only rarely that a female mammal ever responds immunologically to the male gametic antigens as a result of coitus. When a proposed mechanism of suppression of antigenicity of epididymal spermatozoa was tested experimentally, the results indicated that two proteins (uteroglobin and transglutaminase) present in the prostate may be responsible for suppressing sperm antigenicity in the rabbit.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mukherjee, D C -- Agrawal, A K -- Manjunath, R -- Mukherjee, A B -- New York, N.Y. -- Science. 1983 Feb 25;219(4587):989-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6130601" target="_blank"〉PubMed〈/a〉
Keywords:
Acyltransferases/*immunology/metabolism
;
Animals
;
Epididymis/immunology
;
Female
;
Glycoproteins/*immunology
;
*Immune Tolerance
;
Lymphocyte Activation
;
Male
;
Rabbits
;
Semen/enzymology/*immunology
;
Spermatozoa/*immunology
;
Transglutaminases
;
Uteroglobin/*immunology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
Permalink
