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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 19 (1995), S. 475-495 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: A general solution scheme is developed for one-dimensional and non-isothermal consolidation problems for fluid-saturated, porous, thermoelastic media. Two fundamental parameters which describe the coupling effects between thermal, hydraulic and mechanical behaviour are: ratio of thermal and hydraulic diffusivity and ratio of thermomechanical deformabilities in drained and undrained conditions. The solution scheme has been applied to the nuclear waste disposal problem. A solution for a thermoporoelastic rock mass containing a decaying heat source is presented. Numerical results show that coupling effects are most pronounced for low permeability and high porosity media such as deep compressible clays. This corresponds to a low value of the ratio of hydraulic and thermal diffusivities and a high value of the ratio of deformabilities in drained and undrained conditions.Comparison with numerical simulations taking into account the non-linear and non-reversible behaviour of the rock mass is presented. It shows that the thermoelastic model is quite correct for temperature and displacement fields, and gives maxima of the pore pressure and stress elevations.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 20 (1996), S. 673-690 
    ISSN: 0363-9061
    Keywords: tunnel analysis ; new implicit method (NIM) ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: Tunnel excavation is a coupled three-dimensional problem dealing with two different structures: lining and rockmass. For a simple application it is useful to develop simplified methods by treating the problem as plane strain.If the problem of tunnel face advance presents an axisymmetric geometry, then we show that the major parameter governing the ground-interface-lining interaction is the convergence of the tunnel U0 at the moment of the lining installation.The ‘New Implicit Method’ (NIM) presented in this paper makes use of principles similar to those of the ‘convergence-confinement’ method, but it provides a better appreciation of the coupled behaviour of rockmass and lining. For independent time constitutive laws (elasticity and plasticity), we point out that the convergence U0 depends not only on the mechanical behaviour of the rockmass and on the distance from the tunnel face, as predicted by the ‘convergence-confinement’ method, but also on the stiffness of the lining previously set.We present the ‘NIM’ for elastic and perfect elastoplastic rockmasses without dilatancy for many criteria. The development of this new method is based on the results of tunnel calculations with an axisymmetric FEM numerical model that takes into account the three-dimensional aspect of the problem.Using this method is simple and its results agree well with the FEM numerical results. Its accuracy is highly satisfactory for a geotechnical study.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 22 (1998), S. 133-149 
    ISSN: 0363-9061
    Keywords: thermoporoelasticity ; thermoporoplasticity ; Laplace transform ; Stehfest algorithm ; finite element method ; Engineering ; Civil and Mechanical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: Solutions are presented for the behaviour of a layered porous space which contains a decaying heat source. Such a problem arises when high-level nuclear waste is placed in deep underground depositories in deep clayey formations of sedimentary basins. The geometry of the problem is one dimensional and the porous space is constituted by two layers: a deep low permeability layer which contains the nuclear waste disposal and a superficial layer. The solution is used to examine the effects of contrasts of permeability, thermal conductivity and specific heat capacities between the two layers on the large-scale behaviour of the porous space. Results are presented, using realistic data, for the pore pressure and temperature evolution at the heat source centre, and for the vertical displacement of the ground level. The superficial layer has no significant effects on pore pressure, temperature and stress evolution near the heat source centre. The vertical displacement of the ground level is mainly due to the thermal dilatation of the pore water, so it decreases with an increasing of permeability of the superficial layer. The solution of the time-dependent problem is carried out by applying Laplace transforms to the field variables, obtaining solutions and then using numerical methods to invert the transformed solutions. Comparisons with numerical simulations taking into account the non-linear and non-reversible behaviour of the rock mass are presented. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Publication Date: 2011-03-25
    Description: Arising from M. A. Nowak, C. E. Tarnita & E. O. Wilson 466, 1057-1062 (2010); Nowak et al. reply. Nowak et al. argue that inclusive fitness theory has been of little value in explaining the natural world, and that it has led to negligible progress in explaining the evolution of eusociality. However, we believe that their arguments are based upon a misunderstanding of evolutionary theory and a misrepresentation of the empirical literature. We will focus our comments on three general issues.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836173/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836173/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abbot, Patrick -- Abe, Jun -- Alcock, John -- Alizon, Samuel -- Alpedrinha, Joao A C -- Andersson, Malte -- Andre, Jean-Baptiste -- van Baalen, Minus -- Balloux, Francois -- Balshine, Sigal -- Barton, Nick -- Beukeboom, Leo W -- Biernaskie, Jay M -- Bilde, Trine -- Borgia, Gerald -- Breed, Michael -- Brown, Sam -- Bshary, Redouan -- Buckling, Angus -- Burley, Nancy T -- Burton-Chellew, Max N -- Cant, Michael A -- Chapuisat, Michel -- Charnov, Eric L -- Clutton-Brock, Tim -- Cockburn, Andrew -- Cole, Blaine J -- Colegrave, Nick -- Cosmides, Leda -- Couzin, Iain D -- Coyne, Jerry A -- Creel, Scott -- Crespi, Bernard -- Curry, Robert L -- Dall, Sasha R X -- Day, Troy -- Dickinson, Janis L -- Dugatkin, Lee Alan -- El Mouden, Claire -- Emlen, Stephen T -- Evans, Jay -- Ferriere, Regis -- Field, Jeremy -- Foitzik, Susanne -- Foster, Kevin -- Foster, William A -- Fox, Charles W -- Gadau, Juergen -- Gandon, Sylvain -- Gardner, Andy -- Gardner, Michael G -- Getty, Thomas -- Goodisman, Michael A D -- Grafen, Alan -- Grosberg, Rick -- Grozinger, Christina M -- Gouyon, Pierre-Henri -- Gwynne, Darryl -- Harvey, Paul H -- Hatchwell, Ben J -- Heinze, Jurgen -- Helantera, Heikki -- Helms, Ken R -- Hill, Kim -- Jiricny, Natalie -- Johnstone, Rufus A -- Kacelnik, Alex -- Kiers, E Toby -- Kokko, Hanna -- Komdeur, Jan -- Korb, Judith -- Kronauer, Daniel -- Kummerli, Rolf -- Lehmann, Laurent -- Linksvayer, Timothy A -- Lion, Sebastien -- Lyon, Bruce -- Marshall, James A R -- McElreath, Richard -- Michalakis, Yannis -- Michod, Richard E -- Mock, Douglas -- Monnin, Thibaud -- Montgomerie, Robert -- Moore, Allen J -- Mueller, Ulrich G -- Noe, Ronald -- Okasha, Samir -- Pamilo, Pekka -- Parker, Geoff A -- Pedersen, Jes S -- Pen, Ido -- Pfennig, David -- Queller, David C -- Rankin, Daniel J -- Reece, Sarah E -- Reeve, Hudson K -- Reuter, Max -- Roberts, Gilbert -- Robson, Simon K A -- Roze, Denis -- Rousset, Francois -- Rueppell, Olav -- Sachs, Joel L -- Santorelli, Lorenzo -- Schmid-Hempel, Paul -- Schwarz, Michael P -- Scott-Phillips, Tom -- Shellmann-Sherman, Janet -- Sherman, Paul W -- Shuker, David M -- Smith, Jeff -- Spagna, Joseph C -- Strassmann, Beverly -- Suarez, Andrew V -- Sundstrom, Liselotte -- Taborsky, Michael -- Taylor, Peter -- Thompson, Graham -- Tooby, John -- Tsutsui, Neil D -- Tsuji, Kazuki -- Turillazzi, Stefano -- Ubeda, Francisco -- Vargo, Edward L -- Voelkl, Bernard -- Wenseleers, Tom -- West, Stuart A -- West-Eberhard, Mary Jane -- Westneat, David F -- Wiernasz, Diane C -- Wild, Geoff -- Wrangham, Richard -- Young, Andrew J -- Zeh, David W -- Zeh, Jeanne A -- Zink, Andrew -- BB/H022716/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- England -- Nature. 2011 Mar 24;471(7339):E1-4; author reply E9-10. doi: 10.1038/nature09831.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21430721" target="_blank"〉PubMed〈/a〉
    Keywords: *Altruism ; Animals ; *Biological Evolution ; Cooperative Behavior ; Female ; Game Theory ; *Genetic Fitness ; Genetics, Population ; Heredity ; Humans ; Male ; *Models, Biological ; Phenotype ; Reproducibility of Results ; *Selection, Genetic ; Sex Ratio
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 1996-08-16
    Description: The Tax transactivator of the human T cell leukemia virus type I (HTLV-I) exhibits oncogenic properties. A screen for proteins interacting with Tax yielded a complementary DNA (cDNA) encoding the human Int-6 protein. In mice, the Int-6 gene can be converted into a putative dominant negative oncogene after retroviral insertion. Here, Int-6 was localized in the cell nucleus to give a speckled staining pattern superposed to that of the promyelocytic leukemia (PML) protein. The binding of Tax to Int-6 caused its redistribution from the nuclear domains to the cytoplasm. Thus, Int-6 is a component of the PML nuclear bodies and Tax disrupts its normal cellular localization by binding to it.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Desbois, C -- Rousset, R -- Bantignies, F -- Jalinot, P -- New York, N.Y. -- Science. 1996 Aug 16;273(5277):951-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Centre National de la Recherche Scientifique UMR49, Ecole Normale Superieure de Lyon, 69364 Lyon Cedex 07, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8688078" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Cell Nucleus/*chemistry ; Cytoplasm/chemistry ; Eukaryotic Initiation Factor-3 ; Gene Products, tax/analysis/*metabolism ; HeLa Cells ; Humans ; Mice ; *Neoplasm Proteins ; *Nuclear Proteins ; Proto-Oncogene Proteins/analysis/genetics/*metabolism ; Recombinant Fusion Proteins/metabolism ; Transcription Factors/*analysis ; Transfection ; Tumor Suppressor Proteins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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