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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Materials research innovations 3 (2000), S. 250-262 
    ISSN: 1433-075X
    Keywords: Key words Small-specimen testing ; Controlled-flaw method ; Fracture toughness ; Brittle materials ; Finite element analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: ∞ is the crack resistance at ”infinite” crack length. It is convincingly shown that this so-called R-curve equation correctly predicts K∞, which is comparable to the conventionally measured Mode I plain-strain fracture toughness, KIc, of the same material. The fundamental constants in the fracture-mechanics-based equations are discussed, emphasizing the aspects pertinent to the small specimens used in the MDBT. Results are presented on 8 materials: ZnS, glass-ceramic, Si3N4, Ti5Si3, SiC, Ni3Ge, NiAl and Ti-46.5A1-2.1Cr-3.0Nb-0.2W. All are brittle except for the latter two, which undergo slight plastic deformation before fracturing. The resulting values of K∞ are in excellent agreement with published values derived from conventional measurements, providing considerable confidence in the method. where Q is a constant and K∞ is the crack resistance at ”infinite” crack length. It is convincingly shown that this so-called R-curve equation correctly predicts K∞, which is comparable to the conventionally measured Mode I plain-strain fracture toughness, KIc, of the same material. The fundamental constants in the fracture-mechanics-based equations are discussed, emphasizing the aspects pertinent to the small specimens used in the MDBT. Results are presented on 8 materials: ZnS, glass-ceramic, Si3N4, Ti5Si3, SiC, Ni3Ge, NiAl and Ti-46.5A1-2.1Cr-3.0Nb-0.2W. All are brittle except for the latter two, which undergo slight plastic deformation before fracturing. The resulting values of K∞ are in excellent agreement with published values derived from conventional measurements, providing considerable confidence in the method.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-041X
    Keywords: Key words Systemic lupus erythematosis ; AIDS ; HIV ; p36 ; Cytoplasmic inclusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  We describe here the first full-length sequence of a member of a novel gene family encoding a protein in the mouse that we call Lupin. Lupin is homologous to a human protein previously called p36, which was purified from α-interferon-treated cells that formed lupus inclusions. Lupus inclusions are dense intracellular deposits found in endothelial cells and lymphocytes of patients with systemic lupus erythematosis and AIDS. Proteins closely related to Lupin exist in evolutionarily divergent species including Caenorhabditis elegans, Drosophila and zebrafish. At least one other lupin-related gene is expressed in the mouse and in man. Lupin is expressed in mouse embryos and adults, notably in liver, spleen, central nervous system, multiple epithelia and all types of muscle. In skeletal muscle, expression analysis suggests that Lupin associates with the contractile apparatus.
    Type of Medium: Electronic Resource
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