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  • Computer Programming and Software; Aerospace Medicine  (1)
  • α-Globin domain  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 242 (1994), S. 649-652 
    ISSN: 1617-4623
    Keywords: α-Globin domain ; Hypersensitive sites ; Locus control region ; Chromatin structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The distribution of DNase I hypersensitive sites upstream of the chicken α-globin gene cluster was studied. A group of hypersensitive sites with a complex pattern of tissue specificity, including erythroid-specific elements, was found at a distance of 11.5–14.5 kb upstream of the π gene, the first gene in the cluster. The observations indicate that this area, located upstream of the block of AT-rich sequences and MAR sites (at −8 kb) and upstream of the site of permanent DNA attachment to the nuclear matrix (−3 kb), still belongs to the domain of the α-globin genes.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2019-07-13
    Description: Long duration space travel to destinations such as Mars or an asteroid will expose astronauts to extended periods of reduced gravity. Astronauts will use an exercise regime for the duration of the space flight to minimize the loss of bone density, muscle mass and aerobic capacity that occurs during exposure to a reduced gravity environment. Since the area available in the spacecraft for an exercise device is limited and gravity is not present to aid loading, compact resistance exercise device prototypes are being developed. Since it is difficult to rigorously test these proposed devices in space flight, computational modeling provides an estimation of the muscle forces, joint torques and joint loads during exercise to gain insight on the efficacy to protect the musculoskeletal health of astronauts.
    Keywords: Computer Programming and Software; Aerospace Medicine
    Type: GRC-E-DAA-TN19807 , NASA Human Research Program Investigators'' Workshop: Integrated Pathways to Mars; Jan 13, 2015 - Jan 15, 2015; Galveston, TX; United States|Space Radiation Investigators'' Workshop and Behavioral Health and Performance Working Group; Jan 12, 2015 - Jan 15, 2015; Galveston, TX; United States
    Format: application/pdf
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