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  • 5α-Androstane-3α,17β-diol  (1)
  • Carcinogenesis  (1)
  • Center for Marine Environmental Sciences; MARUM  (1)
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  • 1
    facet.materialart.
    Unknown
    Charcoal records of two sediment cores off SW Africa (2012)
    PANGAEA
    In:  Supplement to: Daniau, Anne-Laure; Bartlein, Patrick J; Harrison, S P; Prentice, Iain Colin; Brewer, Simon; Friedlingstein, Pierre; Harrison-Prentice, T I; Inoue, J; Izumi, K; Marlon, Jennifer R; Mooney, Scott D; Power, Mitchell J; Stevenson, J; Tinner, Willy; Andric, M; Atanassova, J; Behling, Hermann; Black, M; Blarquez, O; Brown, K J; Carcaillet, C; Colhoun, Eric A; Colombaroli, Daniele; Davis, Basil A S; D'Costa, D; Dodson, John; Dupont, Lydie M; Eshetu, Z; Gavin, D G; Genries, A; Haberle, Simon G; Hallett, D J; Hope, Geoffrey; Horn, S P; Kassa, T G; Katamura, F; Kennedy, L M; Kershaw, A Peter; Krivonogov, S; Long, C; Magri, Donatella; Marinova, E; McKenzie, G Merna; Moreno, P I; Moss, Patrick T; Neumann, F H; Norstrom, E; Paitre, C; Rius, D; Roberts, Neil; Robinson, G S; Sasaki, N; Scott, Louis; Takahara, H; Terwilliger, V; Thevenon, Florian; Turner, R; Valsecchi, V G; Vannière, Boris; Walsh, M; Williams, N; Zhang, Yancheng (2012): Predictability of biomass burning in response to climate changes. Global Biogeochemical Cycles, 26(4), https://doi.org/10.1029/2011GB004249
    Details
    Publication Date: 2024-01-13
    Description: We analyze sedimentary charcoal records to show that the changes in fire regime over the past 21,000 yrs are predictable from changes in regional climates. Analyses of paleo- fire data show that fire increases monotonically with changes in temperature and peaks at intermediate moisture levels, and that temperature is quantitatively the most important driver of changes in biomass burning over the past 21,000 yrs. Given that a similar relationship between climate drivers and fire emerges from analyses of the interannual variability in biomass burning shown by remote-sensing observations of month-by-month burnt area between 1996 and 2008, our results signal a serious cause for concern in the face of continuing global warming.
    Keywords: Center for Marine Environmental Sciences; MARUM
    Type: Dataset
    Format: application/zip, 2 datasets
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    DATA PANGAEA
  • 2
    Electronic Resource
    Electronic Resource
    Early indicators for carcinogenesis in sex-hormone-sensitive organs
    Amsterdam : Elsevier
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 248 (1991), S. 341-356 
    Details
    ISSN: 0027-5107
    Keywords: Carcinogenesis ; Genotoxicity ; Sex hormones
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0027-5107(91)90067-X
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Role of the pituitary gland in experimental hormonal induction and prevention of benign prostatic hyperplasia in the dog (1979)
    Springer
    Cell & tissue research 204 (1979), S. 367-378 
    Details
    ISSN: 1432-0878
    Keywords: Cyproterone acetate ; 17β-Oestradiol ; 5α-Androstane-3α,17β-diol ; Prostate gland ; Pituitary gland ; Immunocytochemistry ; Dog (beagle)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The antiandrogen, cyproterone acetate (CPA), prevents development of prostatic hyperplasia, induced in castrated dogs by a 6 month-treatment with 5α-androstane-3α,l 7β-diol (A)alone or in combination with 17β-oestradiol (E 2). The immunoperoxidase technique was used to study functional cell types in the pars distalis of the pituitary gland and to detect growth hormone (GH) and prolactin (PRL) target sites in the prostate gland. Homologous radioimmunoassays for estimation of serum canine GH and PRL concentrations were also performed. Treatment with the combinations A + E 2 and A + E 2 + CPA resulted in morphological indications of stimulated GH and PRL cells and depressed gonadotrophs. This correlates well with an increase in PRL-dependent staining in glandular epithelium and fibromuscular tissue of the prostate gland. However, basal serum PRL and GH levels were not significantly affected. Treatment with A and A + E2 stimulated, while additional treatment with CPA clearly suppressed adrenocorticotrophin/melanotrophin (ACTH/MSH) cells. These findings indicate that an endocrine imbalance in hypothalamic-pituitary-adrenal function may be involved in induction and prevention of prostatic hyperplasia in the dog.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233649
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    Paper (German National Licenses)
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