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  • Cell Line  (6)
  • American Association for the Advancement of Science (AAAS)  (6)
  • 1980-1984  (6)
  • 1980  (6)
Collection
Keywords
Publisher
  • American Association for the Advancement of Science (AAAS)  (6)
Years
  • 1980-1984  (6)
Year
  • 1
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    Genes for growth hormone, chorionic somatommammotropin, and growth hormones-like gene on chromosome 17 in humans (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-11
    Description: The human genes for growth hormone (GH), chorionic somatomammotropin (CSH), and a third growth hormone-like gene (GHL) have been located on chromosome 17 in humans. DNA fragments of 2.6, 2.8, and 9.5 kilobase pairs containing GH, CSH, and GHL, respectively, were identified in human genomic DNA, and a 7.5-kilobase DNA fragment related to growth hormone DNA sequences was found in mouse cells. In somatic hybrids of human and mouse cells containing reduced numbers of human chromosomes, but a normal complement of mouse chromosomes, the mouse, 7.5-kolobase DNA fragment was always present, whereas the 2.6-, 2.8-, and 9.5-kilobase human fragments were present only when human chromosome 17 was also present.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Owerbach, D -- Rutter, W J -- Martial, J A -- Baxter, J D -- Shows, T B -- New York, N.Y. -- Science. 1980 Jul 11;209(4453):289-92.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384802" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cell Line ; *Chromosomes, Human, 16-18 ; *DNA/metabolism ; *Genes ; Growth Hormone/*biosynthesis ; Humans ; Hybrid Cells/metabolism ; Mice ; Placental Lactogen/*biosynthesis ; Translocation, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    T-1 cells are HeLa and not of normal human kidney origin (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nelson-Rees, W A -- Flandermeyer, R R -- Daniels, D W -- New York, N.Y. -- Science. 1980 Aug 8;209(4457):719-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7394535" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Line ; Chromosome Banding ; HLA Antigens/analysis ; HeLa Cells/*cytology/immunology ; Humans ; Karyotyping ; Kidney/*cytology/immunology ; Metaphase
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Cell variants showing differential susceptibility to ultraviolet light--induced transformation (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-25
    Description: Six variant clones isolated from a subclone of BALB/3T3-A31 clone were classified into three groups according to their different susceptibilities to cell transformation by ultraviolet light irradiation: highly susceptible, intermediately susceptible, and resistant. All variant clones showed similar susceptibility to cytotoxic effects induced by ultraviolet light.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kakunaga, T -- Crow, J D -- New York, N.Y. -- Science. 1980 Jul 25;209(4455):505-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7394516" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Cell Transformation, Neoplastic/*radiation effects ; Clone Cells ; Dose-Response Relationship, Radiation ; Genetic Variation ; Mice ; Transformation, Genetic/*radiation effects ; *Ultraviolet Rays
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Assignment of the murine interferon sensitivity and cytoplasmic superoxide dismutase genes to chromosome 16 (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-11
    Description: Both hybrids of mouse and human microcells and whole cell hybrids generated by the fusion of primary mouse cells and SV40-transformed human fibroblasts were used to establish the syntenic association of the murine cytoplasmic superoxide dismutase and the interferon sensitivity genes on mouse chromosome 16. This assignment adds two new markers to chromosome 16 and provides another example of an evolutionarily conserved linkage. This finding also provides an animal model both for cellular responsiveness to interferon and for Down's syndrome.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lin, P F -- Slate, D L -- Lawyer, F C -- Ruddle, F H -- New York, N.Y. -- Science. 1980 Jul 11;209(4453):285-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6155698" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Cell Transformation, Viral ; *Chromosomes, Human, 16-18 ; *Genes ; Humans ; Hybrid Cells/drug effects/*physiology ; Interferons/*pharmacology ; Karyotyping ; Mice ; Simian virus 40 ; Superoxide Dismutase/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Time: a new parameter for kinetic measurements in flow cytometry (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-11
    Description: The measure of time was used as an additional parameter on an existing flow cytometer to study the kinetics of enzyme activities and cell-stain interactions. By correlating all fluorescent signals from single cells with time, the dynamics of a reaction can be followed for several minutes. This advanced application of flow cytometry is easily implemented and can be incorporated into any flow cytometer that has two-parameter analysis capability.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Martin, J C -- Swartzendruber, D E -- New York, N.Y. -- Science. 1980 Jan 11;207(4427):199-201.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6153131" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Cells, Cultured/enzymology ; Computers ; Cricetinae ; *Cytological Techniques ; DNA/metabolism ; Esterases/metabolism ; Kinetics ; Mice ; Spectrometry, Fluorescence/methods ; Staining and Labeling
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-25
    Description: Analysis of the cell culture fluid from two new human hepatoma-derived cell lines reveals that 17 of the major human plasma proteins are synthesized and secreted by these cells. One of these cell lines, Hep 3B, also produces the two major polypeptides of the hepatitis B virus surface antigen. When Hep 3B in injected into athymic mice, metastatic hepatocellular carcinomas appear. These cell lines provide experimental models for investigation of plasma protein biosynthesis and the relation of the hepatitis B viru genome to tumorigenicity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Knowles, B B -- Howe, C C -- Aden, D P -- New York, N.Y. -- Science. 1980 Jul 25;209(4455):497-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6248960" target="_blank"〉PubMed〈/a〉
    Keywords: Blood Proteins/*secretion ; Carcinoma, Hepatocellular/immunology/*secretion ; Cell Line ; Electrophoresis, Polyacrylamide Gel ; Hepatitis B Surface Antigens/*analysis ; Humans ; Immunodiffusion ; Liver Neoplasms/immunology/*secretion
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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