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  • Cats  (10)
  • American Association for the Advancement of Science (AAAS)  (10)
  • 1975-1979  (10)
Collection
Publisher
  • American Association for the Advancement of Science (AAAS)  (10)
Years
Year
  • 1
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    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 1978-06-16
    Description: A purified sodium and potassium dependent adenosinetriphosphatase isolated from cat heart was not stimulated by any concentration of ouabain that produced positive inotropy of cat papilliary muscle. Only inhibition of enzyme activity was observed. Concentrations of ouabain used ranged from 3.3 x 10(-10) molar to 5 x 10(-7) molar and produced an increased force of contraction without any evidence of toxicity. The results are inconsistent with a concept that stimulation of sodium pump activity is associated with positive inotropy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Michael, L -- Pitts, B J -- Schwartz, A -- New York, N.Y. -- Science. 1978 Jun 16;200(4347):1287-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/149369" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphatases/*antagonists & inhibitors ; Animals ; Biological Transport, Active/drug effects ; Cats ; Dose-Response Relationship, Drug ; In Vitro Techniques ; Myocardial Contraction/*drug effects ; Myocardium/*enzymology ; Ouabain/*pharmacology ; Potassium/metabolism ; Sodium/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 1978-06-30
    Description: A single injection of 5 or 10 microliters of ferrous or ferric chloride into rat or cat sensorimotor cortex resulted in chronic recurrent focal paroxysmal electroencephalographic discharges as well as behavioral convulsions and electrical seizures. Recurrent focal epileptiform discharge caused by cortical injection of iron salts suggests that the development of human posttraumatic epilepsy may depend, in part, on the neurochemical alterations induced by the principal metallic ions found in whole blood.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Willmore, L J -- Sypert, G W -- Munson, J V -- Hurd, R W -- New York, N.Y. -- Science. 1978 Jun 30;200(4349):1501-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/96527" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cats ; Cerebral Cortex/*drug effects/physiopathology ; *Disease Models, Animal ; Electrophysiology ; Epilepsies, Partial/*chemically induced ; Ferric Compounds ; Ferrous Compounds ; *Iron ; Rats ; Seizures/*chemically induced/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 1978-03-17
    Description: With naloxone as antagonist, a dose-ratio analysis of the depression by morphine of nociceptive neurons in the spinal cord reveals that this opiate depression of single unit activity has the same pharmacological properties as observed with morphine analgesia. This suggests that the opiate receptor, mediating the observed cellular depression, and those mediating analgesia are presumably the same.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yaksh, T L -- New York, N.Y. -- Science. 1978 Mar 17;199(4334):1231-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/204008" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials/drug effects ; Animals ; Cats ; Decerebrate State ; Dose-Response Relationship, Drug ; Morphine/*pharmacology ; Naloxone/*pharmacology ; Nerve Fibers/physiology ; Nociceptors/*drug effects/physiology ; Receptors, Opioid/*physiology ; Spinal Cord/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 1979-06-15
    Description: Rates of cerebral perfusion were obtained from measurements of the disappearance (wash-out) of oxygen-15 after in situ tissue activation with 45-million-volt x-rays. In an anesthetized cat, typical values were 90 milliliters per minute per 100 grams of tissue, with 55 percent wash-out. In a specific radiotherapy patient, the value was 65 milliliters per minute per 100 grams of tissue, with 63 percent wash-out of oxygen-15 through incorporation into tissue water.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hughes, W L -- Nussbaum, G H -- Connolly, R -- Emami, B -- Reilly, P -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1215-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451567" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*blood supply ; Cats ; Humans ; Neoplasms/blood supply ; Oxygen/*blood/radiation effects ; Oxygen Radioisotopes ; *Regional Blood Flow ; X-Rays
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 1978-07-07
    Description: Cats were classically conditioned after the baroreceptor reflexes were abolished by bilateral placement of electrolytic lesions in the nucleus tractus solitarii. The conditioned increases in arterial pressure were more than five times larger than the responses obtained in similarly trained controls. This finding suggests that the baroreceptor reflexes actively inhibit conditioned increases of arterial pressure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nathan, M A -- Tucker, L W -- Serverini, W H -- Reis, D J -- New York, N.Y. -- Science. 1978 Jul 7;201(4350):71-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663640" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Blood Pressure ; Cats ; Conditioning, Classical/physiology ; Disease Models, Animal ; Female ; Heart Rate ; Hypertension/physiopathology ; Male ; Medulla Oblongata/*physiology ; Pressoreceptors/*physiology ; Reflex/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 1978-01-13
    Description: Intracellular recordings were made from trigeminal motoneurons of normally respiring, unanesthetized cats during naturally occurring sleep. The transition from quiet to active sleep was accompanied by tonic motoneuron hyperpolarization. Stimulation of the reticular formation induced a depolarizing potential in trigeminal motoneurons during quiet sleep and a hyperpolarizing potential during active sleep. The results provide a synaptic explanation for the phenomenon of reticular response reversal and insights into the basic mechanisms controlling motor activity during the sleep states.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nakamura, Y -- Goldberg, L J -- Chandler, S H -- Chase, M H -- New York, N.Y. -- Science. 1978 Jan 13;199(4325):204-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/202025" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cats ; Electric Stimulation ; Membrane Potentials ; Motor Neurons/*physiology ; Reflex ; Reticular Formation/*physiology ; Sleep/*physiology ; Sleep, REM/physiology ; Synapses/physiology ; Trigeminal Nerve/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 1978-04-07
    Description: Prostacyclin, a potent, naturally occurring prostaglandin exerts a variety of cardiovascular and cellular actions of potential value in acute myocardial ischemia. These properties include the reduction of systemic blood pressure without changing heart rate, the lowering of coronary vascular and total peripheral resistance, the inhibition of platelet aggregation and the concomitant formation of thromboxane B2, and the reduction of the release of lysosomal enzymes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lefer, A M -- Ogletree, M L -- Smith, J B -- Silver, M J -- Nicolaou, K C -- Barnette, W E -- Gasic, G P -- New York, N.Y. -- Science. 1978 Apr 7;200(4337):52-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/345441" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Pressure/drug effects ; Cats ; Coronary Circulation/drug effects ; Coronary Disease/drug therapy ; Epoprostenol/*pharmacology/therapeutic use ; Heart Rate/drug effects ; Hemodynamics/*drug effects ; In Vitro Techniques ; Lysosomes/drug effects/enzymology ; Myocardial Contraction/drug effects ; Platelet Aggregation/drug effects ; Prostaglandins/*pharmacology ; Thromboxanes/blood ; Vascular Resistance/drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 1979-09-21
    Description: Long-term amphetamine administration to cats (a mean of 8.75 milligrams per kilogram twice daily for 10 days) produced large decreases (40 to 67 percent in serotonin and its major metabolite, 5-hydroxyindoleacetic acid, in all brain regions examined. This treatment also produced several behaviors that are dependent on depressed central serotonergic neurotransmission, and which normally are elicited exclusively by hallucinogenic drugs. Short-term amphetamine administration (15 mg/kg) did not produce these behaviors and resulted in small decreases in brain serotonin and no change in 5-hydroxyindoleacetic acid. These data are discussed in the context of monoamine theories of schizophrenia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Trulson, M E -- Jacobs, B L -- New York, N.Y. -- Science. 1979 Sep 21;205(4412):1295-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/572992" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/drug effects ; Brain/*metabolism ; Brain Chemistry/*drug effects ; Cats ; Dextroamphetamine/*pharmacology ; Disease Models, Animal ; Female ; Humans ; Hydroxyindoleacetic Acid/metabolism ; Schizophrenia/*physiopathology ; Serotonin/*metabolism ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 1979-05-04
    Description: Single cell activity and local field potentials in parastriate cortex of cats and rabbits were studied during a Pavlovian discrimination procedure. Cell activity was selectively modified; conditioned changes occurred in response either to the reinforced stimulus or to the unreinforced one, but not to both. Cells exhibiting conditioned alteration in response to the unreinforced stimulus are thought to participate in specialized circuits mediating conditioned inhibition.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉de Toledo-Morrell, L -- Hoeppner, T J -- Morrell, F -- New York, N.Y. -- Science. 1979 May 4;204(4392):528-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432660" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Animals ; Cats ; Cerebral Cortex/physiology ; Conditioning (Psychology)/*physiology ; Neural Inhibition ; Rabbits ; Reinforcement (Psychology) ; Visual Cortex/*physiology ; Visual Perception/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 1979-08-03
    Description: The hypothesis that the action of hallucinogenic drugs is mediated by a depression of the activity of brain serotonergic (raphe) neurons was tested by examining the behavioral effects of d-lysergic acid diethylamide (LSD) while studying the activity of raphe neurons in freely moving cats. Although the results provide general support for the hypothesis, there were several important dissociations. (i) Low doses of LSD produced only small decreases in raphe unit activity but significant behavoiral changes; (ii) LSD-induced behavioral changes outlasted the depression of raphe unit activity; and (iii) raphe neurons were at least as responsive to LSD during tolerance as they were in the nontolerant condition.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Trulson, M E -- Jacobs, B L -- New York, N.Y. -- Science. 1979 Aug 3;205(4405):515-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451617" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/*drug effects ; Brain Stem/*physiology ; Cats ; Lysergic Acid Diethylamide/*pharmacology ; Neurons/drug effects/*physiology ; Raphe Nuclei/drug effects/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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