Publication Date:
1983-06-03
Description:
By analyzing the hearts of quail-chick chimeras, it was found that neural crest cells at the level of occipital somites 1 to 3 migrate to the region of the aorticopulmonary septum. Bilateral removal of this neural crest population prior to migration causes malformation of the aorticopulmonary septum resulting in common arterial outflow channels or transposition of the great vessels.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kirby, M L -- Gale, T F -- Stewart, D E -- ND 17063/ND/ONDIEH CDC HHS/ -- New York, N.Y. -- Science. 1983 Jun 3;220(4601):1059-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6844926" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Aorta/*embryology
;
Chick Embryo
;
Chimera
;
Coturnix
;
Heart/embryology
;
Heart Defects, Congenital/embryology
;
Humans
;
Lung/*embryology
;
Neural Crest/*physiology
;
Swine
;
Transposition of Great Vessels/embryology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
Permalink
