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  • Analytical Chemistry and Spectroscopy  (6)
  • Space Radiation  (6)
  • 1
    ISSN: 0306-042X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A method has been developed for quantitative determination of pinaverium-bromide, a quaternary ammonium derivative with papaverine-like activity, in human serum. The method involves a chloroform extraction of serum spiked with N-(6,6-dimethyl bicyclo[3.1.1]2-heptenyl-ethoxyethyl)perhydro-1,4-oxazine as internal standard. After evaporation of the solvent, and reduction of the residue with Raney-Nickel, the internal standard and the reduced pinaverium-bromide are re-extracted from the reaction mixture with toluene and analysed isothermally on a fused silica column coated with OV-101. Although chemical ionization with methane revealed intense protonated molecular ions for both pinaverium-bromide and the internal standard, selectivity and sensitivity were significantly lower in comparison with electron impact ionization at 70 eV. Therefore, quantification was performed in the electron impact mode by single ion monitoring of the common fragment ion at m/z 100.2. A linear detector response was observed up to 160 ng ml-1. A within-run assay precision better than 2% CV (n=5) was found, and a detection limit of 1 ng pinaverium-bromide ml-1 of serum was attained.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    X-Ray Spectrometry 3 (1974), S. 59-63 
    ISSN: 0049-8246
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Description / Table of Contents: Measurement of the extracellular fluid volume (ECFV) in the human body is an useful means of recognizing pathological conditions. X-ray fluorescence spectrometry allows a simple and accurate determination of the difusion space of bromide ions, from which the ECFV value can be calculated. The method consists of the quantitative determination of stable bromine (80Br) at low concentration in biological fluids, using the Br Kα line. A simultaneous study run with a radioactive tracer (82Br) allowed us to check the validity of the procedure.
    Notes: Le volume de liquide extracellualaire (LEC) chez l'homme estun parameétre important pour la deétection de certins eétats pathologiques. La spectromeétrie de fluorescence X permet de mesurer avec une bonne preécision I'espace de deffusion de I'ion bromure et d'en deédrire la valeur du volume de LEC. La meéthode consiste en un dosage direct du brome stabel (80Br) à faible concentration dans les liquides biologiques, en utilisant la raie Br Kα Une étude paralleéle au moyen d'un radiotraceur (82Br)permet de tester la valcur de la meéthode.
    Additional Material: 3 Ill.
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  • 3
    ISSN: 0049-8246
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Description / Table of Contents: It can be interesting to determine bromine in a number of biological solutions, although the choice of method is made difficult by the occurrence of other elements. Yet, X-ray fluorescence spectrometric analysis appears suitable under certain conditions. The technique described here is based on the use of a non-dispersive X-ray fluorescence spectrometer, with 109Cd radioactive isotope as an excitation source. The factors studied are the system geometry, the volume of samples, the choice of cells and the reproducibility of measurements. Special conditions, as imposed by the collection of biological samples, are also considered.
    Notes: Il peut être intkréssant de doser le brome dans certains liquides biologiques. La présence d'autres éléments limite le choix des méthodes. L'analyse par spectrométric de fluorescence X paraít adaptée sous certaines conditions. Les auteurs décrivent une technique utilisant un spectromètre de fluorescence X non dispersif, dont la source d'excitation est constituée par un isotope radioactif: le Cadmium 109. Les facteurs de géométrie, le volume des échantillons, Ie choix des cellules, la reproductibilité des mesures sont étudiés, compte tenu des conditions imposées par le recueil des échantillons biologiques.
    Additional Material: 10 Ill.
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 7 (1980), S. 515-520 
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Quantification of bile acids has been carried out by selected ion monitoring and by repetitive scanning. The latter method has been explored critically and found to be very suitable. A 24 h collection of feces was submitted to Soxhlet extraction. The extract was purified on Servachrom XAD-2, and separated into sulfated and nonsulfated fractions over DEAP-Sephadex-LH20. Conjugated and sulfated bile acids were enzymatically deconjugated and desulfated prior to permethylation. Deuterated bile acid derivatives were added as external standards and an aliquot was injected onto a capillary column of SE-52. The reconstructed chromatogram traces of specific ions were integrated to quantify known bile acids. Spectra of all metabolites were available for identification purposes simultaneously.
    Additional Material: 6 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 7 (1978), S. 249-253 
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Raman spectra of both polycrystalline samples and single crystals of CsAlCl4 and RbAlCl4 (space group Pnma (D2h16)) have been recorded in the temperature range 298-80 K.As for the other chloroaluminates, we find the four characteristic bands of the tetrahedral AlCl4- anion at 353, 128, 485-503, 180-187 cm-1 and 356, 127, 486-505 and 180-187 cm-1, respectively, for the salts CsAlCl4 and RbAlCl4. The Raman spectra of single crystals of these two compounds are similar and show that these two salts are isostructural. An assignment of the observed bands is proposed. The results are compared with those for the polyatomic cation (nitrosyl and ammonium) tetrachloroaluminates.
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  • 6
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The crystal structure of NaAlCl4 (a = 10.322(3) Å, b = 9.886(3) Å, c = 6.167(2) Å, Z = 4, space group P212121) was refined to final R and Rω values of 0.025 and 0.039 respectively, for 1240 reflections with I〉2σ(I). The thermal motion of the AlCl4- anion is in keeping with the TLS rigid-body analysis. Crystal and polycrystalline samples of this compound were studied by Raman scattering and an assignment of the observed bands was proposed. The Raman spectrum was compared with those of all members of alkaline (Li, Na, K, Rb, Cs) and pseudo-alkaline (NH4+, NO+) tetrachloroaluminates in the solid state.
    Additional Material: 5 Ill.
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  • 7
    Publication Date: 2019-07-18
    Description: The ENTICE experiment is one of two instruments that make up the HNX mission. The experimental goal of ENTICE is to measure with high precision the elemental abundances of all nuclei with Z between 10 and 82. This will enable us to determine if the injection mechanism for the cosmic ray accelerator is controlled by FIP or Volatility and to study the mix of nucleosynthetic processes that contribute to the galactic cosmic ray source. The ENTICE experiment utilizes the dE/dx-C method of charge determination and consists of silicon dE/dx detectors, Cherenkov detectors with two different refractive indices, and a fiber hodoscope. We will describe the instrument and its performance based on beam tests of a prototype instrument.
    Keywords: Space Radiation
    Type: ICRC 2001 Conference; Aug 07, 2001 - Aug 15, 2001; Hamburg; Germany
    Format: text
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  • 8
    Publication Date: 2019-07-18
    Description: The ECCO (Extremely-heavy Cosmic-ray Composition Observer) instrument is one of two instruments which comprise the HNX (Heavy Nuclei Explorer) mission. The principal goal of ECCO is to measure the age of galactic cosmic ray nuclei using the actinides (Th, U, Pu, Cm) as clocks. As a bonus, ECCO will search with unprecedented sensitivity for long-lived elements in the superheavy island of stability. ECCO is an enormous array (23 sq. m) of BP-1 glass track-etch detectors, and is based on the successful flight heritage of the Trek detector which was deployed externally on Mir. We present a description of the instrument, estimates of expected performance, and recent calibrations which demonstrate that the actinides can be resolved from each other with good charge resolution.
    Keywords: Space Radiation
    Type: ICRC 2001 Conference; Aug 07, 2001 - Aug 15, 2001; Hamburg; Germany
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  • 9
    Publication Date: 2019-07-18
    Description: The primary scientific objectives of HNX, which was recently selected by NASA for a Small Explorer (SMEX) Mission Concept Study, are to measure the age of the galactic cosmic rays (GCR) since nucleosynthesis, determine the injection mechanism for the GCR accelerator (Volatility or FIP), and study the mix of nucleosynthetic processes that contribute to the source of GCRs. The experimental goal of HNX is to measure the elemental abundances of all individual stable nuclei from neon through the actinides and possibly beyond. HNX is composed of two instruments: ECCO, which measures elemental abundances of nuclei with Z greater than or equal to 72, and ENTICE. which measures elemental abundances of nuclei with Z between 10 and 82. We describe the mission and the science that can be addressed by HNX.
    Keywords: Space Radiation
    Type: 27th ICRC 2001 Conference; Aug 07, 2001 - Aug 15, 2001; Hamburg; Germany
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  • 10
    Publication Date: 2019-07-17
    Description: The ENTICE experiment is one of two instruments which make up the HNX mission. The experimental goal of ENTICE is to measure with high precision the elemental abundances of all nuclei with 10〈=Z〈=82. This will enable us to distinguish between possible injection mechanisms for the galactic cosmic ray accelerator such-as those dependent upon volatility or first ionization potential, and to study the mix of nucleosynthetic processes that contribute to the galactic cosmic ray source. The ENTICE experiment utilizes the dE/dx-C method of charge determination and consists of silicon dE/dx detectors, Cherenkov detectors with two different refractive indices, and a scintillating fiber hodoscope. The geometrical factor of the instrument is 8m2.sr. We will present a description of the instrument and its expected performance based on beam tests and a balloon flight of a prototype instrument.
    Keywords: Space Radiation
    Type: International Cosmic Ray Conference; Aug 07, 2001 - Aug 15, 2001; Hamburg; Germany
    Format: text
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