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  • Aged  (8)
  • American Association for the Advancement of Science (AAAS)  (8)
  • 1975-1979  (8)
Collection
Keywords
Publisher
  • American Association for the Advancement of Science (AAAS)  (8)
Years
Year
  • 1
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    Preferential utilization of free cholesterol from high-density lipoproteins for biliary cholesterol secretion in man (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-04-07
    Description: High- and low-density lipoproteins carrying free cholesterol labeled with 3H or 14C were administered to a patient with a bile fistula. The free cholesterol from high-density lipoproteins was more rapidly incorporated into biliary cholesterol than the free cholesterol from low-density lipoproteins. These findings show that the liver in man selectively utilizes and secretes the free cholesterol from a particular lipoprotein.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schwartz, C C -- Halloran, L G -- Vlahcevic, Z R -- Gregory, D H -- Swell, L -- New York, N.Y. -- Science. 1978 Apr 7;200(4337):62-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/204996" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Bile/*metabolism ; Cholesterol/blood/*metabolism ; Coronary Disease/metabolism ; Erythrocytes/metabolism ; Female ; Humans ; Lipoproteins, HDL/*metabolism ; Lipoproteins, LDL/*metabolism ; Liver/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Reversible cerebral atrophy in recently abstinent chronic alcoholics measured by computed tomography scans (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-06-02
    Description: Eight chronic alcoholics received repeated computed tomography scans. Four, who maintained abstinence and functionally improved, showed partially reversible cerebral atrophy. Two nonabstinent patients and two abstinent patients who had completed functional improvement before the first scan showed no change in atrophy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carlen, P L -- Wortzman, G -- Holgate, R C -- Wilkinson, D A -- Rankin, J C -- New York, N.Y. -- Science. 1978 Jun 2;200(4345):1076-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/653357" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Aged ; Alcoholism/*pathology/radiography/therapy ; Atrophy ; Brain/*pathology/radiography ; Female ; Humans ; Male ; Middle Aged ; Tomography, X-Ray Computed
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Care of the aged: old problems in need of new solutions (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: Long-term care for the aged in the United States is overly dependent upon the nursing home. This hospital-like model for long-term care is particularly inappropriate since it imposes a medical solution on a variety of social problems. An adequate long-term care program requires a range of resources in the community as well as in institutions; sheltered housing options seem a desirable alternative to the nursing home. To ensure the quality of nursing home care, the present focus on setting standards for care activities should be abandoned in favor of a focus on care outcomes (physical, mental, and social). In an effort to change our present perverse incentives in the nursing home industry, the proposal is made that nursing homes be reimbursed according to the degree to which patient outcomes meet predicted outcomes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kane, R L -- Kane, R A -- New York, N.Y. -- Science. 1978 May 26;200(4344):913-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/417403" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Financing, Government ; Health Facilities, Proprietary ; *Homes for the Aged/economics ; Humans ; Long-Term Care/*methods ; *Nursing Homes/economics/standards ; Socioeconomic Factors ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    B lymphocyte antigens in sicca syndrome (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-03-31
    Description: All individuals tested in this study with sicca syndrome, a human autoimmune disease, bear two immunologically distinct and genetically unrelated B lymphocyte antigens that appear similar to the immune response associated (Ia) antigens of the mouse. The genes coding for these two antigens are present in only 37 and 24 percent of normal controls. In animal models Ia antigen genes are closely linked to immune response genes. Our findings suggest that two such genes may be required for the development of sicca syndrome.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Moutsopoulos, H M -- Chused, T M -- Johnson, A H -- Khudsen, B -- Mann, D L -- New York, N.Y. -- Science. 1978 Mar 31;199(4336):1441-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/415366" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Aged ; Autoimmune Diseases/*immunology ; B-Lymphocytes/*immunology ; Female ; *Genes, MHC Class II ; Genetic Linkage ; HLA Antigens/analysis/genetics ; Humans ; Isoantigens/*analysis/genetics ; Male ; Middle Aged ; Sjogren's Syndrome/genetics/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Cohort mortality for prostatic cancer among United States nonwhites (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-06-09
    Description: In recent decades, age-adjusted mortality rates from prostatic cancer have risen precipitously among blacks, remaining unchanged among whites. It is now the most common cancer among United States black males. When nonwhite mortality rates were examined by age and birth cohort, it was found that peak rates occurred at every age in the cohort of 1896 to 1900, and declined thereafter. This presages an arrest and reversal of the time trend in summary mortality rates as more recent nonwhite cohorts reach the ages of maximum risk.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ernster, V L -- Selvin, S -- Winkelstein, W Jr -- New York, N.Y. -- Science. 1978 Jun 9;200(4346):1165-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/653361" target="_blank"〉PubMed〈/a〉
    Keywords: *African Continental Ancestry Group ; Age Factors ; Aged ; European Continental Ancestry Group ; Humans ; Male ; Middle Aged ; Prostatic Neoplasms/*mortality
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Selective phospholipid adsorption and atherosclerosis (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: Disaturated (fully saturated) lecithins adsorb onto solid surfaces more readily than lecithins in which one or both fatty acids are unsaturated. If saturated lecithins adsorb to arterial walls as they do to glass and polystyrene surfaces, there may be increased probability of atherosclerosis when the disaturated lecithin content of plasma is elevated. Analyses of lecithins in plasma samples from patients with myocardial infarction, and from patients with premature atherosclerosis but with low concentrations of plasma cholesterol and triglycerides, are consistent with the hypothesis that a high concentration of disaturated lecithin in plasma may be a significant risk factor for atherosclerosis, independent of triglyceride and cholesterol concentrations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gershfeld, N L -- New York, N.Y. -- Science. 1979 May 4;204(4392):506-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/581915" target="_blank"〉PubMed〈/a〉
    Keywords: Adsorption ; Adult ; Aged ; Arteriosclerosis/blood/*etiology ; Coronary Disease/*blood ; Fatty Acids, Unsaturated ; Female ; Humans ; Male ; Middle Aged ; Myocardial Infarction/blood ; *Phosphatidylcholines/blood ; Pulmonary Surfactants/blood ; Structure-Activity Relationship ; Temperature
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Erythrocytes: a new cell type for the evaluation of insulin receptor defects in diabetic humans (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: Human erythrocytes have specific insulin receptors. When studied in an insulin radioreceptor assay, erythrocytes from adult-onset, nonobese diabetic subjects bound at least 42 percent less insulin than the normal subjects at insulin concentrations from 0.1 to 100 nanograms per milliliter. The diabetic subjects had 190 insulin receptor sites per cell as compared with the 380 insulin receptor sites per cell for the normal subjects. The deficit of insulin binding in the diabetic subject was thus associated with a fewer number of insulin binding sites per cell with little or no change in affinity. The erythrocyte is a readily available cell for the evaluation of cellular insulin receptor activity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Robinson, T J -- Archer, J A -- Gambhir, K K -- Hollis, V W Jr -- Carter, L -- Bradley, C -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):200-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451590" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Aged ; Diabetes Mellitus/*blood/metabolism ; Erythrocyte Membrane/*metabolism ; Erythrocytes/*metabolism ; Female ; Humans ; Insulin/metabolism ; Male ; Middle Aged ; Receptor, Insulin/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Health: whose responsibility? (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-02-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Strauss, Anselm L -- Sipe, Jack C -- Knowles, John H -- New York, N.Y. -- Science. 1978 Feb 10;199(4329):597-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11643441" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; *Health ; Human Rights ; Humans ; *Moral Obligations ; Poverty ; Social Justice ; *Social Responsibility ; Socioeconomic Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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