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  • ASTROPHYSICS  (16)
  • Metabolic systems  (2)
  • 1975-1979  (18)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 17 (1979), S. 223-229 
    ISSN: 1741-0444
    Keywords: Metabolic systems ; Modelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A case study illustrates the application of systems theory to the analysis of data from nonrepeatable experiments with relatively few data points. The specific problem considered is the compartmental modelling in the human of the metabolic pathways of orally-administered methionine using tolerance test data. Attention is restricted to linear models, and concentrates on the determination of parsimonious structures (i.e. with as few parameters as possible) and their physiological interpretation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 17 (1979), S. 216-222 
    ISSN: 1741-0444
    Keywords: Metabolic systems ; Modelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The adequacy of present-day measurement techniques for the compartmental modelling of metabolic systems is investigated using numerical examples and analysis of experimentally-obtained plasma clearance curves. It is concluded that the model parameters obtained are often of questionable accuracy. The situation can be improved by careful monitoring of experimental conditions and judicious spacing of data points on the response curve, but the work shows a clear need for a continuous (or semicontinuous) method of monitoring plasma concentration. To resolve ambiguities between models equally plausible on physiological grounds, it is necessary to monitor the dynamics of internal variables, for example, of the concentration in the liver (which is nowadays possible noninvasively).
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  • 3
    Publication Date: 2011-08-17
    Description: A previous analysis of the manifestations of charged-pion-decay secondary electrons in interstellar cloud material is extended to include those contributions to the Galactic radio and soft gamma-ray backgrounds that are directly attributable to energetic secondaries. The equilibrium distribution of secondary electrons in dense interstellar clouds is calculated, synchrotron emissivity from isolated interstellar clouds is examined, and it is shown how the value of the magnetic field in these clouds may be determined by observing the radio emission in their directions. The contribution that such clouds make to the integrated radio background is evaluated, and the Galactic distribution of bremsstrahlung gamma rays that arise from interactions of secondary electrons with thermal material in dense clouds is computed. The results indicate that a magnetic field of no more than 80 microgauss is characteristic of dense clouds and that the integrated synchrotron radiation from secondary electrons in interstellar clouds will contribute a significant fraction of the nonthermal brightness along the Galactic equator even if the mean cloud field is as low as 35 microgauss.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal; vol. 221
    Format: text
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  • 4
    Publication Date: 2011-08-17
    Description: Several models for the radio emission from immediate postoutburst supernovae are examined under the assumption that the expanding remnant consists of a homogeneously mixed distribution of relativistic particles, magnetic field, and thermal plasma. The evolutionary models are: (1) an adiabatic expansion model; (2) a model incorporating the existence of a central pulsar; and (3) variations on the first two models in which relativistic electrons are accelerated either instantaneously or over an extended period of time and in which ionization, bremsstrahlung, synchrotron, Compton, and expansion losses are explicitly included. The character of the radio emission expected from these models is quite dissimilar. Whereas in adiabatic expansion models the emission is expected to increase slowly and become most intense at high frequencies, in models involving a central pulsar the emission should increase rapidly with a maximum flux density that is the same at all frequencies. The theoretical evolution of the radio emission for each model is compared with observations of SN 1970g.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal; vol. 220
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  • 5
    Publication Date: 2011-08-17
    Description: It is suggested that grand unified field theories with spontaneous symmetry breaking in the very early big bang can lead more naturally to a baryon-symmetric cosmology with a domain structure than to a totally baryon-asymmetric cosmology. The symmetry is broken in a randomized manner in causally independent domains, favoring neither a baryon nor an antibaryon excess on a universal scale. Arguments in favor of this cosmology and observational tests are discussed.
    Keywords: ASTROPHYSICS
    Type: Physical Review Letters; 43; July 23
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  • 6
    Publication Date: 2019-06-27
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal; 195; Jan. 1
    Format: text
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  • 7
    Publication Date: 2019-06-27
    Description: The most frequently used formulations of the gravitational field are discussed and a standard set of models for the gravity fields of the earth, moon, sun, and other massive bodies in the solar system are defined. The formulas are presented in standard forms, some with instructions for conversion. A point-source or inverse-square model, which represents the external potential of a spherically symmetrical mass distribution by a mathematical point mass without physical dimensions, is considered. An oblate spheroid model is presented, accompanied by an introduction to zonal harmonics. This spheroid model is generalized and forms the basis for a number of the spherical harmonic models which were developed for the earth and moon. The triaxial ellipsoid model is also presented. These models and their application to space missions are discussed.
    Keywords: ASTROPHYSICS
    Type: NASA-SP-8117
    Format: application/pdf
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  • 8
    Publication Date: 2019-06-27
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal; vol. 227
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  • 9
    Publication Date: 2019-06-27
    Description: A search has been made for the simplest amino acid - glycine - in Sgr B2, Ori A, and seven other molecular clouds. Six different lines were sought ranging from 83.4 GHz down to 22.7 GHz, and radio telescopes at Parkes, New South Wales, Kitt Peak, Arizona, and Onsala, Sweden, were used. On the assumption of reasonable values for excitation temperature and Boltzmann distributions over rotational energy states, upper limits of column densities for glycine of a few times 10 to the 12th per sq cm to a few times 10 to the 14th per sq cm were typically established in the sources surveyed. Glycine appears to be less abundant than ethanol or ethyl cyanide in molecular clouds such as Sgr B2 and Ori A.
    Keywords: ASTROPHYSICS
    Type: Royal Astronomical Society; vol. 186
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  • 10
    Publication Date: 2019-06-27
    Description: Grand unified theories (GUT) such as SU(5), with spontaneous symmetry breaking, can lead more naturally to a globally baryon symmetric big bang cosmology with a domain structure than to a totally asymmetric cosmology. The symmetry is broken at random in causally independent domains, favoring neither a baryon nor an antibaryon excess on a universal scale. Because of the additional freedom in the high-energy physics allowed by such GUT gauge theories, new observational tests may be possible. Arguments in favor of this cosmology and various observational tests are discussed.
    Keywords: ASTROPHYSICS
    Type: NASA-TM-80306
    Format: application/pdf
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