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  • ASTROPHYSICS  (1,702)
  • AERODYNAMICS  (954)
  • Cell & Developmental Biology  (705)
  • 1985-1989  (1,854)
  • 1980-1984  (1,507)
Collection
Keywords
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Year
  • 1
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    Hydrogen-deficient atmospheres for cool carbon stars (1985)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: Motivated by recent work which hints at a possible deficiency of hydrogen in non-Mira N-type carbon stars and to further explore the parameter space of chemical composition, computations have been made of a series of hydrogen-deficient models for carbon stars. For these models Teff = 3000 K, and log g = 0.0. Solar abundances are used for all elements except for carbon (which is enhanced to give C/O = 1.05), hydrogen, and helium. As the fractional abundance of hydrogen is decreased, being replaced by helium, the temperature-optical depth relation is affected only slightly, but the temperature-pressure relation is changed. The most striking change in the emergent flux is the decrease of the H(-) peak at 1.65 micron compared with the blackbody peak at 1.00 micron.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 292; 228-230
    Format: text
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  • 2
    Electronic Resource
    Electronic Resource
    Perturbation of the switch-on of transcriptase activity in intermediate subviral particles from reovirus (1982)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 112 (1982), S. 10-18 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Intermediate subviral particles (ISVP) derived from reovirus represent a simple model system for the switch-on of transcriptase function. In such particles the endogenous transcriptase is present in a switched-off form, one step removed from the switched-on state. Switch-on of transcriptase function is an active process in this system and can be triggered by K+ ions. A variety of agents which affect gene expression in cells were tested for an effect on switch-on in ISVP. Marked effects on switch-on in ISVP were observed with a diverse group of test agents, including DMSO and other solvents, BUdR, TdR, caffeine, theophylline, and temperature. The correlation in response between ISVP and cells suggests that the ISVP system may be useful as a model for studying the biochemical mechanisms underlying the perturbative effects of such agents on gene expression in cells.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041120104
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Pharmacological profile of the substituted beta-lactam L-659,286: A member of a new class of human PMN elastase inhibitors (1989)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 39 (1989), S. 47-53 
    Details
    ISSN: 0730-2312
    Keywords: elastase inhibitors ; β-lactams ; lung damage ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Human polymorphonuclear leukocyte elastase (PMN elastase) is inhibited by L-659, 286 (7α-methoxy-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triaz-in-3-yl)thio]methyl]-5-thia-1-aza-6R-bicyclo [4.2.O]oct-2-ene-2-pyrrolidine carboxamide-5,-dioxide) with a Ki of 0.4 μM. This inhibition is time-dependent, rapid, and only slowly reversible, with a t1/2 of 〉 3 days at 25°C. L-659, 286 is also highly selective for PMN elastase, as it does not inhibit thrombin, trypsin, papain, plasmin, chymotrypsin, or cathepsin G. L-659, 286 administered intratracheally inhibits lung damage caused by administration via the same route of human PMN elastase into hamsters. In marmosets, L-659, 286 is cleared from blood very rapidly after an intravenous injection but is recovered in bronchoalveolar lavage fluid for several hours after intratracheal administration.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240390106
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  • 4
    Electronic Resource
    Electronic Resource
    Morphological and ultrastructural characterization of mammalian spermatozoa processed for flow cytometric DNA analyses (1984)
    New York, NY : Wiley-Blackwell
    Gamete Research 10 (1984), S. 339-351 
    Details
    ISSN: 0148-7280
    Keywords: spermatozoa ; flow cytometry ; DNA staining ; nuclear morphology ; ultrastructure ; mammals ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The morphological and ultrastructural changes that occur during preparation of porcine, bovine, and murine spermatozoa for flow cytometric quantification of the relative DNA content of the X- and Y-chromosome-bearing sperm populations were examined. Ejaculated spermatozoa from the boar and bull were washed using a series of dimethyl sulfoxide (DMSO) solutions prior to fixation, whereas the epididymal mouse spermatozoa were washed only in phosphate-buffered saline (PBS). Spermatozoa from all three species were then fixed in ethanol and processed for fluorochrome staining by a treatment regimen consisting of sulfhydryl reduction and proteolysis. The processed sperm nuclei were stained for DNA with the fluorochrome, 4′-6-diamidino-2-phenylindole (DAPI) before quantification by flow cytometry. Scanning and transmission electron micrographs of sperm heads taken at various steps of the preparation and staining procedures show 1) that the rigorous washing procedure disrupted the plasma and outer acrosomal membranes, 2) that ethanol fixation resulted in removal of the outer membranes and disintegration of the nuclear envelope, and 3) that thiol and proteolysis treatment removed the remaining cellular organelles including the tail and rapidly induced partial decondensation of the tightly packed chromatin. Sequential micrographs showed that the nuclear matrix of all three species increased in thickness about twofold during the preparation and staining. Consequently, the harsh procedures currently used for quantitative staining of DNA for high-resolution flow cytometric analyses destroy most cellular organelles and thereby prevent simultaneous characterization of DNA content and other sperm cell constituents.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1120100402
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  • 5
    Electronic Resource
    Electronic Resource
    Inhibition of the metabolism of ram spermatozoa by derivatives of α-chlorohydrin (1981)
    New York, NY : Wiley-Blackwell
    Gamete Research 4 (1981), S. 203-217 
    Details
    ISSN: 0148-7280
    Keywords: α-chlorohydrin ; antifertility agent ; ram ; sperm metabolism ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The effects of the male antifertility agent, α-chlorohydrin, six of its derivatives, and glycidol were studied on the metabolism of washed ram spermatozoa in vitro with fructose as substrate. The α-chlorohydrin derivatives were the amino, the phosphorylated, and four glycol-bridge (ketal) compounds. All compounds except glycidol, in a concentration between 0.1 and 100 mM, reduced the aerobic glycolsis and/or oxidation of fructose. However, there was not a high correlation between the ability of these compounds to inhibit the metabolism of ram spermatozoa in vitro and their antifertility activity when administered to male rats. Other factors are clearly involved in their antifertility activity, eg, the concentration of the compounds in the epididymis and their conversion of either more or less spermicidal compounds in the body.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1120040305
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  • 6
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    VLBI observations of the nucleus of Centaurus A (1982)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Keywords: ASTROPHYSICS
    Type: Extragalactic radio sources; Aug 03, 1981 - Aug 07, 1981; Albuquerque, NM
    Format: text
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  • 7
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    Arcsecond positions for milliarcsecond VLBI nuclei of extragalactic radio sources. IV - Seventeen sources (1986)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: VLBI measurements of time delay and delay rate at 2.29 and 8.42 GHz on baselines of 10,000 km have been used to determine the positions of the milliarcsecond nuclei in 17 extragalactic radio sources with estimated accuracies of 0.1 to 0.3 arcsec. The observed sources are part of an all-sky VLBI catalog of milliarcsecond radio sources. In addition, slightly improved positions are presented for 101 sources originally reported by Morabito et al. (1983). Arcsecond positions have now been determined for 836 sources.
    Keywords: ASTROPHYSICS
    Type: Astronomical Journal (ISSN 0004-6256); 92; 546-551
    Format: text
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  • 8
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    Observations of NGC 7027 from 5.2 to 7.5 microns - The detection of Ni II and additional dust features (1983)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: NGC 7027 was observed with a multichannel grating spectrometer from 5.2 to 7.5 microns at a spectral resolving power of 120-200. Two new dust emission features are resolved at 5.62 and 6.95 microns, and for the first time the Ni II fine-structure line at 6.64 microns is detected. It is shown that a single molecular dust constituent might account for six of the nine observed dust features between 2 and 14 microns. The strength of the Ni II line indicates either that Ni is not depleted in the neutral gas, or that the line is formed at high density.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 274; 666-670
    Format: text
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  • 9
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    A search for fragmentation debris near Ursa Major Stream stars (1982)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: Accretion models of planet formation and the early cratering history of the solar system suggest that planet formation is accompanied by a cloud of debris resulting from accumulation and fragmentation. A rough estimate of the infrared luminosities of debris clouds is presented for comparison with measured 10-micron luminosities of young stars. New measurements of 13 F, G, and K main-sequence stars of the Ursa Major Stream, which is thought to be about 270-million years old, place constraints on the amount of debris which could be present near these stars.
    Keywords: ASTROPHYSICS
    Type: Icarus; 50; Apr. 198
    Format: text
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  • 10
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    Toward a descriptive model of solar particles in the heliosphere (1988)
    In:  CASI
    Details
    Publication Date: 2013-08-31
    Description: During a workshop on the interplanetary charged particle environment held in 1987, a descriptive model of solar particles in the heliosphere was assembled. This model includes the fluence, composition, energy spectra, and spatial and temporal variations of solar particles both within and beyong 1 AU. The ability to predict solar particle fluences was also discussed. Suggestions for specific studies designed to improve the basic model were also made.
    Keywords: ASTROPHYSICS
    Type: Interplanetary Particle Environment. Proceedings of a Conference; p 3-13
    Format: application/pdf
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