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  • 1
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    Origins of serotonin innervation of forebrain structures (1977)
    In:  Other Sources
    Details
    Publication Date: 2011-08-17
    Description: The tryptophan hydroxylase activity and high-affinity uptake of (3H) serotonin ((3H)5-HT) were measured in five discrete brain regions of rats following lesions of the dorsal or median raphe nuclei. Dorsal raphe lesions reduced enzyme and uptake activity in the striatum only. Median raphe lesions reduced activities in the hippocampus, septal area, frontal cortex, and, to a lesser extent, in the hypothalamus. These data are consistent with the suggestion that the dorsal and median raphe nuclei are the origins of two separate ascending serotonergic systems - one innervating striatal structures and the other mesolimbic structures, predominantly. In addition, the data suggest that measurements of high-affinity uptake of (3H)5-HT may be a more reliable index of innervation than either 5-HT content or tryptophan hydroxylase activity.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Experimental Neurology; 56; July 197
    Format: text
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  • 2
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    Histamine H2 receptor - Involvement in gastric ulceration (1976)
    In:  Other Sources
    Details
    Publication Date: 2011-08-16
    Description: The involvement of the H1 and H2 receptors for histamine in the pathogenesis of gastric ulcers was investigated in rats. Metiamide, an H2 receptor antagonist, reliably reduced ulceration produced by stress alone or by a combination of stress and aspirin. In contrast, pyrilamine, which blocks only the H1 receptor, was without effect under these same conditions. The results support the hypothesis that histamine mediates both stress and stress plus aspirin induced ulceration by a mechanism involving the H2 receptor.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Life Sciences; 18; 1976
    Format: text
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  • 3
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    Synaptosomal uptake of hypothalamic monoamines and recovery of pituitary-adrenal activity following medial forebrain bundle lesions in rats (1979)
    In:  Other Sources
    Details
    Publication Date: 2011-08-17
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Neuroendocrinology; 28; 1979
    Format: text
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  • 4
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    Natural laminar flow data from full-scale flight and wind-tunnel experiments (1981)
    In:  Other Sources
    Details
    Publication Date: 2018-12-01
    Description: Experimental results obtained at NASA Langley during studies of natural laminar flow (NLF) over commercially produced aircraft surfaces are reported. The general aviation aircraft examined were light aircraft, yet displayed NLF extents close to the maximum available and equivalent to high performance business aircraft flying envelopes. Sublimating chemicals and acoustic detection techniques were employed to measure the boundary layer transition. Theoretical predictions of boundary layer stability were found to match well with the experimental data, with consideration given to both swept wings and the amplitudes of allowable waves on the airfoil surfaces. The presence of the NLF on the airfoil surfaces confirmed the benefits available from use of composite materials for airfoil surfaces.
    Keywords: AERODYNAMICS
    Format: text
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  • 5
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    Piloted simulation study of the effects of an automated trim system on flight characteristics of a light twin-engine airplane with one engine inoperative (1986)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: A simulation study was conducted to investigate the piloting problems associated with failure of an engine on a generic light twin-engine airplane. A primary piloting problem for a light twin-engine airplane after an engine failure is maintaining precise control of the airplane in the presence of large steady control forces. To address this problem, a simulated automatic trim system which drives the trim tabs as an open-loop function of propeller slipstream measurements was developed. The simulated automatic trim system was found to greatly increase the controllability in asymmetric powered flight without having to resort to complex control laws or an irreversible control system. However, the trim-tab control rates needed to produce the dramatic increase in controllability may require special design consideration for automatic trim system failures. Limited measurements obtained in full-scale flight tests confirmed the fundamental validity of the proposed control law.
    Keywords: AERODYNAMICS
    Type: NASA-TP-2633 , L-16147 , NAS 1.60:2633
    Format: application/pdf
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  • 6
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    Effect of angular inflow on the vibratory response of a counter-rotating propeller (1985)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: This report presents the results of a propeller vibratory stress survey on the Fairey Gannet aircraft aimed at giving an assessment of the difference in vibratory response between single and counter-rotating propeller operation in angular inflow. The survey showed that counter-rotating operation of the propeller had the effect of increasing the IP response of the rear propeller by approximately 25 percent over comparable single-rotation operation while counter-rotating operation did not significantly influence the IP response of the front propeller.
    Keywords: AERODYNAMICS
    Type: NASA-CR-174819 , NAS 1.26:174819
    Format: application/pdf
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