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  • 1
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    Origins of serotonin innervation of forebrain structures (1977)
    In:  Other Sources
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    Publication Date: 2011-08-17
    Description: The tryptophan hydroxylase activity and high-affinity uptake of (3H) serotonin ((3H)5-HT) were measured in five discrete brain regions of rats following lesions of the dorsal or median raphe nuclei. Dorsal raphe lesions reduced enzyme and uptake activity in the striatum only. Median raphe lesions reduced activities in the hippocampus, septal area, frontal cortex, and, to a lesser extent, in the hypothalamus. These data are consistent with the suggestion that the dorsal and median raphe nuclei are the origins of two separate ascending serotonergic systems - one innervating striatal structures and the other mesolimbic structures, predominantly. In addition, the data suggest that measurements of high-affinity uptake of (3H)5-HT may be a more reliable index of innervation than either 5-HT content or tryptophan hydroxylase activity.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Experimental Neurology; 56; July 197
    Format: text
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  • 2
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    Histamine H2 receptor - Involvement in gastric ulceration (1976)
    In:  Other Sources
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    Publication Date: 2011-08-16
    Description: The involvement of the H1 and H2 receptors for histamine in the pathogenesis of gastric ulcers was investigated in rats. Metiamide, an H2 receptor antagonist, reliably reduced ulceration produced by stress alone or by a combination of stress and aspirin. In contrast, pyrilamine, which blocks only the H1 receptor, was without effect under these same conditions. The results support the hypothesis that histamine mediates both stress and stress plus aspirin induced ulceration by a mechanism involving the H2 receptor.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Life Sciences; 18; 1976
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  • 3
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    Synaptosomal uptake of hypothalamic monoamines and recovery of pituitary-adrenal activity following medial forebrain bundle lesions in rats (1979)
    In:  Other Sources
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    Publication Date: 2011-08-17
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Neuroendocrinology; 28; 1979
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  • 4
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    Results of acoustic tests of a Prop-Fan model (1987)
    In:  Other Sources
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    Publication Date: 2019-06-28
    Description: Results of acoustic tests in a low speed open jet anechoic wind tunnel are presented for a counter rotation Prop-Fan model. The model tested had 5 front and 5 rear rotor blades with swept planform. Noise spectra are presented showing the influence of operating and configuration variables such as: (1) power absorption, (2) tip speed, (3) rotor-rotor spacing, (4) power split between the front and rear blade rows, (5) variation of the RPM ratio between front and rear blade rows, (6) tractor versus pusher (pylon effects), and (7) angle of attack. In addition to model scale results, calculated levels derived from test are presented showing the influence of the above variables on Effective Perceived Noise Level of a 13.1 ft diameter Prop-Fan at a flyover distance of 1500 ft. It was found that the strongest effects are caused by tip speed and power absorption. A significant finding was that there is an optimum operating tip speed for minimum noise for a given power absorption. Effects of other parametric variations are generally small but measurable. In order to minimize noise to meet airplane certification limits, operation at moderate tip speeds and power absorption is shown to be desirable. Accuracy of predicted Effective Perceived Noise Level is shown to be good with the best accuracy in the 590 to 670 ft/sec tip speed range.
    Keywords: ACOUSTICS
    Type: AIAA PAPER 87-1894
    Format: text
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  • 5
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    Results of acoustic tests of a prop-fan model (1988)
    In:  Other Sources
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    Publication Date: 2019-07-12
    Keywords: ACOUSTICS
    Type: Journal of Aircraft (ISSN 0021-8669); 25; 653-658
    Format: text
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