ISSN:
0947-3440
Keywords:
Lofendazam analogues
;
1,5-Benzodiazepines
;
Circular dichroism
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A route to optically active variously substituted 4-methyl- and 4-methyl-7-substituted 1,3,4,5-tetrahydro-2H-1,5-benzo-diazepin-2-ones as analogues of commercially available Lofendazam (7-chloro-5-phenyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one, 1) was developed. Fortyone variously substituted optically active compounds having the same configuration were prepared and the UV and CD spectra of the parent compounds bearing no additional substitution in the benzene ring are discussed.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1995199510261
Permalink