ISSN:
0170-2041
Keywords:
Amination
;
Nitroisoquinolines
;
Calculations, FMO
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
5- and 8-Nitroisoquinoline and some of their derivatives are aminated in a liquid ammonia solution of potassium permanganate to yield the corresponding 6- and 7-amino compounds. From 5,7-dinitroisoquinoline the 6,8-diamino derivative is obtained; 1-nitroisoquinoline has been found to be unreactive. FMO calculations made for a few nitroisoquinolines confirm the experimentally observed regioselectivity of the amination.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1990199001124
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