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  • Springer  (65)
  • National Academy of Sciences  (21)
  • American Association for the Advancement of Science (AAAS)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    World journal of microbiology and biotechnology 8 (1992), S. 550-551 
    ISSN: 1573-0972
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    ISSN: 1432-0827
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin , Physik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    European journal of clinical pharmacology 21 (1982), S. 287-291 
    ISSN: 1432-1041
    Schlagwort(e): tolmesoxide ; hypertension ; pharmacokinetics
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Summary Tolmesoxide is a new, direct-acting vasodilator drug for use in the management of both hypertension and cardiac failure. In 6 essential hypertensives inadequately controlled by combined β-blocker and diuretic therapy (average supine blood pressure 178/103 mm Hg) the addition of tolmesoxide (300–900 mg daily) was associated with a significant improvement in blood pressure control (average supine blood pressure 161/89 mmHg). The effect of food on the pharmacokinetics and pharmacodynamics of tolmesoxide have also been studied because, particularly at higher doses, the drug has been associated with upper gastrointestinal upset and it has been empirically recommended that it be taken with food. The blood pressure and heart rate responses were not significantly different when tolmesoxide was taken fasting or with food. Food resulted in a significant reduction in the peak plasma tolmesoxide concentration (2.14 µg/ml compared to 2.97 µg/ml) and a significant increase in the time to reach peak plasma concentration (1.67 h compared to 0.63 h). Although there was no impairment of its hypotensive effect, food significantly altered the pharmacokinetics of tolmesoxide and may therefore be useful in reducing the gastrointestinal disturbance associated with its use. In the treatment of inadequately controlled hypertension, tolmesoxide has a limited role as an alternative vasodilator.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Chromosoma 73 (1979), S. 179-190 
    ISSN: 1432-0886
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Transcriptional activity during early mammalian embryogenesis was examined in 2 cell, 4–8 cell and late morula/early blastocyst mouse embryos. Zona pellucida-free embryos were obtained after pronase digestion followed by a PMSF wash to inhibit proteolytic activity. The embryos were then lysed with NP40 detergent and spread for electron microscopy according to Miller and Bakken (1972). pre-mRNA transcription was observed at all stages. Comparison of growing RNP chain lengths revealed statistically significant differences in the distribution of shorter fibrils between the successive developmental stages examined. The number of shorter fibrils was lower in the 4–8 cell stage than in either of the two other stages. Transcription complexes of ribosomal type were detected only in 4–8 cell and morula/blastocyst embryos. Structures resembling replication loops were observed within chromatin from all stages. Similar loop-like structures as well as individually transcribed RNP fibrils were also occasionally found on fibres emerging from mitotic chromosomes. The results are discussed in the context of recent findings concerning genetic expression in early mouse embryos.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Biology and fertility of soils 18 (1994), S. 241-244 
    ISSN: 1432-0789
    Schlagwort(e): Earthworms ; Food location ; Population density ; Aporrectodea ; Microscolex ; Organic manure Cocoon
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Geologie und Paläontologie , Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract A field experiment was established to assess the effects of additional organic matter on earthworm populations. Bags of soil (15 cm deep) were placed in a pasture at Balhannah, South Australia, at the beginning of autumn 1991. The bags were initially seeded with five individuals ofAporrectodea trapezoides, and 250 g dried sheep manure was added to most bags. Manure was added either in pellet or milled form, and applied either on the surface, in the 5–10 cm layer, or evenly dispersed over 15 cm. In harvests during weeks 7,9, and 11 after the start of the experiment,A. trapezoides and three other species,A. caliginosa, A. rosea, andMicroscolex dubius, were recovered from the bags. Bags with added manure had significantly higher numbers of each species than bags with no manure. During the 4-week sampling period (weeks 7–11) the numbers ofM. dubius recovered per bag decreased, whileA. rosea increased. Total earthworm numbers were not influenced by either the form or the location of application of the manure. Earthworms were sampled from three depths, 0–5, 5–10, and 10–15 cm. Both numbers and biomass of earthworms were positively correlated with the location of the manure. Cocoons ofAporrectodea spp. were more abundant when the manure was milled and evenly dispersed, and were consistently located in the lower soil layers, regardless of the form or location of manure.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    ISSN: 1432-0789
    Schlagwort(e): Key words Earthworms ; Burrowing behaviour ; Food location ; Aporrectodea Microscolex
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Geologie und Paläontologie , Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract A series of experiments was conducted over 96 h in 240-mm-deep soil microcosms, to assess the effect of the presence and distribution of sheep manure over the soil surface on the vertical and horizontal distribution of burrows and numbers of the earthworms Aporrectodea trapezoides and Microscolex dubius. Within some microcosms the dung was placed on half of the soil surface and this caused aggregation, with over two-thirds of the earthworms being found in the soil directly under the manure. The presence of surface-applied sheep manure caused both species to aggregate in the surface soil. In contrast, without manure, A. trapezoides was evenly distributed throughout the soil profile while M. dubius aggregated in the deeper soil. The pattern of burrow construction was also influenced by the presence of surface manure. In the absence of manure, burrows of both species were evenly distributed through the soil, but in the presence of surface manure M. dubius constructed proportionally more burrows close to the surface. Both species constructed approximately twice the burrow area in the absence than in the presence of surface manure. For both species the daily rate of burrow construction decreased over the experimental period. From these data we inferred that there was more widespread and active foraging behaviour in both species when organic food material was scarce. M. dubius differed from A. trapezoides in that it more strongly concentrated foraging activity in the vicinity of the manure food source.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Oecologia 7 (1971), S. 127-135 
    ISSN: 1432-1939
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary Biocontent of the above-ground parts of ground vegetation in an alder-birch woodland was between 75 and 581.3 Kcal/m2 (16.05 and 137.70 g/m2). Species peaks did not necessarily coincide with the highest values for total ground vegetation. Ground vegetation litter biocontent was 1848.4 Kcal/m2 at the beginning of the study (April 1966) but rapidly fell to near 700 Kcal/m2 and remained near this level until April 1968. Net production by the above ground parts of the ground vegetation was 1016 Kcal/m2/yr (277.86 g/m2/yr) and 1142 Kcal/m2/year (280.20 g/m2/yr) in 1966–1967 and 1967–1968 respectively, measured as mortality plus net biocontent changes. These estimates were compared with those based on biocontent changes. Ground vegetation net primary production was not much smaller than tree litter fall (circa 1450 Kcal/m2/yr).
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    Entomologia experimentalis et applicata 49 (1988), S. 75-82 
    ISSN: 1570-7458
    Schlagwort(e): aphid-resistance ; lucerne ; alfalfa ; Medicago sativa ; spotted alfalfa aphid ; Therioaphis trifolii f. maculata ; antibiosis ; bioassay
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract In autumn 1981 there were widespread reports of a reduced level of antibiosis in lucerne crops and field trials where cultivars selected for resistance to the aphid, Therioaphis trifolii f. maculata, had been used. On our field trial, the plot of ‘CUF 101’ lucerne was infested to a level about 40% of that on the aphid-susceptible ‘Hunter River’, compared with an average of about 3% over the two years before and the two years after. An experimental study of possible causes using a bioassay technique on cloned plants representing the spectrum of resistance in CUF 101 indicated that loss of resistance was temporary and occurred apparently randomly among the tests, but that certain treatments increase the frequency of its occurrence. Lowered temperatures and the use of either young regrowth or senescent lucerne, each increased the frequency of loss of resistance. Inundation of lucerne by large numbers of aphids did not affect the expression of resistance directly, but the few progeny that survived to adulthood on partly-resistance lucerne were habituated and were then able to interact with the plants to increase the apparent frequency of breakdown of resistance. Plants which showed the loss of resistance developed aphid populations between 4x ad 25x those when they expressed their normal resistance level. Investigations suggest that the situation in autumn 1981 may have been the result of a prolonged and massive immigration of aphids into lucerne crops, which, on the aphid resistant cultivars allowed surviving aphids to exploit maximally the combined effects of factors causing some loss of resistance.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Entomologia experimentalis et applicata 63 (1992), S. 177-185 
    ISSN: 1570-7458
    Schlagwort(e): Parasitic hymenoptera ; biological control ; aphid pests
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract As an integral part of a programme to attempt the biological control of several crop-infesting aphid pests in Australia by the introduction of specific hymenopterous parasites, a laboratory technique to try to predict their likely effectiveness in the field, was developed with the aim of improving selection of natural enemies in future. It was based on demonstrating whether the parasites attack a greater proportion of their hosts with increased host density, i.e. whether they show a Type 3 functional response (Holling, 1959). To overcome the problem of super-parasitisation at low densities when a parasite is confined with aphids on one plant (van Lenteren & Bakker, 1976) we used several plants in a large cage, all with the same density of host aphids. A parasite released into such a cage searches for and attacks the aphids on one plant, then leaves it to repeat the process on a second plant, and so on. After a standard exposure time the parasitisation rate is estimated separately for the aphids on each plant and the average performance of the parasite calculated. Using this technique for seven parasites introduced into Australia for biological control of crop aphids, only one, Aphidius salicis Halliday, attacking carrot aphid showed a Type 3 response.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    ISSN: 1572-8838
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract The best available state-of-charge tests are identified for the case of 1800 mAh alkaline zinc manganese dioxide cells. These are not sufficiently good for the design of impedance based hardware.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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