ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 118 (1994), S. 263-269 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The oxygen-binding properties of haemolymph from laboratory-reared Artemia franciscana were investigated in vitro. Adult female brine shrimp without eggs were acclimated to seven different combinations of salinity and oxygen. The oxygen affinity (P50) of unprocessed haemolymph rises with acclimation oxygen partial pressure (PO2) up to normoxic values, after which no influence of oxygen occurs. The increase in P50 with acclimation PO2 can be explained by the change in proportion of each of three different haemoglobins in the haemolymph. Salinity acclimation has no effect on haemolymph P50. The effects of the different major salts [NaNO3, NaCl, Ca(NO3)2, Mg(NO3)2], pH, and the metal-binding ligand EGTA on the oxygen-binding properties of buffered haemolymph (of shrimp acclimated to 10‰ salinity) were also studied. Little or no effect of these salts could be found. A small Bohr effect (pH 6.5 to 9.1, ϕ=-0.11) was noted. Addition of EGTA caused a significant decrease of the oxygen affinity at concentrations up to 50 mmoll-1.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A culture of juvenile Sepia officinalis L. was kept during summer 1985 in the aquaria of the “Station Marine”, Wimereux, France. During the first four months of juvenile development, oxygen consumption under increasing hypoxia was measured with a closed respirometer. The experiments revealed a high regulatory capacity of juvenile S. officinalis. The critical oxygen concentrations were calculated and their ontogenetical evolution was studied. The critical oxygen concentration increased with increasing development. A linear relationship emerged between the critical oxygen concentration and the logarithm of the wet weight [COc (mg O2 l-1)=-0.393+0.893×log10(W w )]. The decreasing regulatory capacity of growing S. officinalis is most probably related to adaptations to a changing ecological environment during development. Another possibility is a physiological change, most probably related to the shift from embryonic to adult hemocyanin.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Adult Sepia officinalis L. were caught in June 1984, in the coastal waters of Wimereux (France). Deposition of the eggs took place in the seawater aquaria of the “Station Marine”. The oxygen consumption of S. officinalis was measured during embryonic and juvenile development. Aerobic metabolism occurs as soon as the early embryonic Stage 21. Oxygen diffuses through the initially thick egg shell; the oxygen level in the perivitelline liquid reaches a maximal value just before hatching (116.7±6.9 mm Hg). Hatchings display only a slight increase in oxygen consumption compared to embryos in the last stage of development. Respiration experiments with 40 d old juveniles showed that oxygen consumption increases with temperature, but is not affected by photoperiod. Experiments under increasing hypoxia revealed that S. officinalis juveniles are good regulators and maintain a constant oxygen consumption in the range of 4 to 7 mg O2l-1. Juveniles successfully recover from an hypoxic stress of 2 mg O2l-1 maintained for 1 h. This suggests that the respiratory pigments (pre-hemocyanins) of 40 d-old juveniles have a high oxygen affinity and/or that these juveniles have the ability to adapt to anaerobic conditions.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 107 (1976), S. 143-160 
    ISSN: 1432-072X
    Keywords: New nucleoside-peptide antibiotic ; Chitin biosynthesis ; Structure elucidation ; Mass spectrometry ; Streptomyces tendae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Der Streptomycet Tü 901, Streptomyces tendae, bildet ein antifungisch wirkendes Nukleosid-Antibioticum, Nikkomycin. Als Angriffsort kommt die Chitinsynthese in Frage. Mit Hilfe der Massenspektrometrie und des chemischen Abbaus konnten Uracil, eine Aminohexuronsäure und eine neue, einen Pyridinring enthaltende Aminosäure nachgewiesen werden.
    Notes: Abstract From the fermentation broth of Streptomyces tendae Tü 901 a substance was isolated, which inhibits the growth of several fungi. The new antibiotic affects the chitchin biosynthesis. Its structure was identified by mass spectrometry of the products obtained after chemical degradation. Nikkomycin is a nucleoside-peptide antibiotic consisting of uracil, an amino hexuronic acid and a new amino acid containing a pyridin ring.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 149 (1988), S. 220-224 
    ISSN: 1432-072X
    Keywords: Nitrite reductase ; Catalase ; Hematin activation ; Lactobacillus plantarum ; L. curvatus ; L. sake ; Starter cultures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The effect of the addition of hematin on the activities of nitrite reductase and catalase was studied with cell suspensions of strains of lactobacillus species. In cells of Lactobacillus plantarum grown under aerobic or anaerobic conditions nitrite reductase was present. This activity was not exhibited by cells of L. curvatus and only rarely by L. sake. In addition, catalase activity was detected in aerobically grown cells only, with all strains of L. plantarum and L. sake; again L. curvatus was devoid of this activity. Ammonia was formed as the main product of nitrite reduction by L. plantarum. With lactate as the electron donor, the end products of carbohydrate catabolism were carbon dioxide, acetoin and acetate. The activities of nitrite reductase and catalase in strains of lactobacillus species may be used for optimizing the quality of starter cultures applied for the production of raw sausages.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 9 (1976), S. 387-392 
    ISSN: 1432-1041
    Keywords: Defibrinogenisation ; peripheral arterial disease ; clinical trial design ; medical statistics ; sequential analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effect of Arwin® on peripheral arterial occlusive disease has been studied in two multicentre trials. In the first, in cases of severe peripheral arterial circulatory disorders of the lower extremities with permanent rest pain (stages III and III + IV according to Fontaine) Arwin® had a better intravenous therapeutic effect than anticoagulant treatment. A further trial was done to investigate whether subcutaneous administration of Arwin® would have an effect superior to classical conservative therapy with vasodilator drugs in this type of disease. The results were assessed by sequential analysis. Arwin® was again shown to be a much better treatment. Problems of medical documentation and statistics are discussed in relation to the value of sequential analysis.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 44 (1993), S. S33 
    ISSN: 1432-1041
    Keywords: Nephrotoxicity ; Cell repair ; drug induced nephrotoxicity ; growth factors ; specific proteinuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Nephrotoxic drugs may account for approximately at least 20 % of clinically observed cases of acute renal failure in whom tubular lethal or sublethal damage is a predominant finding. Acute toxic tubular cell injury is characterized by loss of cellular polarization, intrinsic energy deficiency, calcium overload, release of toxic proteases and free oxygen radicals, derangement of the cytoskeleton, and vacuolar transformation of brush border microvilli. These events may finally lead to irreversible cell death. Shedding of membrane enzymes and cytoskeletal components in urine (kidney tissue proteinuria) may serve as a noninvasive early marker for assessing tubular cell injury. Successful recovery of renal function depends on early repair of lethally or sublethally damaged nephrons, in which intrinsic nephrogenic adaptive and proliferative responses cooperate in concert with auto/para/-juxtacrine growth promoting factors and cytokines. Exogenously administered growth factors may enhance renal cell recovery, as shown in animal models. Increased expression of immediate early genes in tubular cells after renal injury reflects the ongoing mitogenic activity necessary for reepithelialization and remodeling (new, polarized, differentiated cells). Further progress in understanding the molecular mechanisms of renal tubular injury will probably influence the diagnostic modalities and therapeutic approaches to acute drug induced renal failure.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 101-108 
    ISSN: 1432-1041
    Keywords: Cardiac glycosides ; methyl proscillaridin ; plasma concentrations ; electrocardiogram ; bioavailability ; 86Rb-erythrocyte assay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The aim of this study was to obtain data about the pharmacological properties of a new glycoside derivative in man. Plasma concentrations and ECG parameters were measured after oral and intravenous administration of a single dose of 1.2 mg methyl proscillaridin in 16 healthy volunteers, using a strictly randomized, two-period change-over design. Glycoside concentrations were measured using a modified86Rb-erythrocyte-assay. QT-duration, corrected for frequency (QTc), was the principal variable measured in the ECG. By either route, there was a maximum plasma level after 1 hour, which had decreased to a minimum at 3 hours, followed by a second peak at 4 to 10 hours (orally〉iv). From 10 to 72 hours the concentrations decreased with a median t 1/2 of 23.3 hours (iv) and 33.0 hours (orally). Comparison of the ratio of plasma concentrations following oral and iv administration resulted in a bioavailability of 69 % using the 48 hour plasma levels, and 59 % using the areas under the concentration-time curves. The mean QTc was maximally shortened to 28 msec at 1 hour after iv and to 19 msec at 10 hours after the oral dose. A distinct similarity between time-concentration and time-QTc curves was seen after the initial distribution phase, both after oral and intravenous administration. The new derivative shows a rapid elimination. Its bioavailability is reasonably high.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Informatik, Forschung und Entwicklung 14 (1999), S. 95-108 
    ISSN: 0949-2925
    Keywords: Schlüsselwörter:Sicherheitsarchitektur, Mehrseitige Sicherheit, Konfigurierung, Aushandlung, Interoperabilität ; Key words: Security architecture, multilateral security, configuration, negotiation, interoperability ; CR Subject Classifications: C.2.4, H.5.2, K.4.4, K.6.5
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Abstract. We present a prototype of a security architecture. It enables developers and users of distributed applications to employ multilateral security. Users can express their security goals (e.g. confidentiality, anonymity, integrity and accountability) and select the according cryptographic mechanisms. The communicating parties negotiate security goals and mechanisms to secure the communication. Therefore the architecture comprises components for configuration and negotiation as well as so called security gateways. Building on secure local systems it allows to set up flexible multilateral security for distributed applications.
    Notes: Zusammenfassung. Wir stellen eine prototypische Implementierung einer Sicherheitsarchitektur vor. Sie unterstützt Nutzer und Entwickler verteilter Anwendungen bei der Umsetzung bzw. Integration von mehrseitiger Sicherheit. Nutzer können Schutzziele wie Vertraulichkeit, Anonymität, Integrität und Zurechenbarkeit anwendungsbezogen formulieren und ihnen zugeordnete kryptographische Mechanismen konfigurieren. Der konkrete Schutz einer Kommunikation über Datennetze wird zwischen den Partnern ausgehandelt. Heterogenen Anforderungen der Nutzer bzw. Applikationen und heterogenen Eigenschaften der Schutzmechanismen wird durch Architekturkomponenten für Konfigurierung und Aushandlung sowie sog. Sicherheitsgateways Rechnung getragen. Die Architektur setzt jeweils lokal sichere Basissysteme voraus und ermöglicht darauf aufbauend flexible mehrseitige Sicherheit für verteilte Anwendungen.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...