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  • 1
    Publication Date: 1992-06-19
    Description: Because human immunodeficiency virus (HIV) can be transmitted as cell-free virus or as infected cells (cell-associated virus), vaccines must protect against infection by both viral forms. Vaccine-mediated protection of nonhuman primates against low doses of cell-free HIV-1, HIV-2, or simian immunodeficiency virus (SIV) has been demonstrated. It is now shown that multiple immunizations of chimpanzees with HIV-1 antigens protected against infection with cell-associated virus. Protection can persist for extended periods (one animal had not been exposed to viral antigens for 1 year before challenge). These results show that it is possible to elicit long-lasting protective immunity against cell-associated HIV-1.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fultz, P N -- Nara, P -- Barre-Sinoussi, F -- Chaput, A -- Greenberg, M L -- Muchmore, E -- Kieny, M P -- Girard, M -- New York, N.Y. -- Science. 1992 Jun 19;256(5064):1687-90.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Microbiology, University of Alabama, Birmingham 35294.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1609280" target="_blank"〉PubMed〈/a〉
    Keywords: AIDS Vaccines ; Animals ; HIV Antigens/immunology/therapeutic use ; HIV Infections/*prevention & control ; HIV-1/*immunology ; Immunity, Active ; Immunization, Passive ; Immunologic Memory ; Leukocytes, Mononuclear/*immunology ; Longitudinal Studies ; Pan troglodytes/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2006-10-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ahuja, Sunil K -- Aiuti, Fernando -- Berkhout, Ben -- Biberfeld, Peter -- Burton, Dennis R -- Colizzi, Vittorio -- Deeks, Steven G -- Desrosiers, Ronald C -- Dierich, Manfred P -- Doms, Robert W -- Emerman, Michael -- Gallo, Robert C -- Girard, Marc -- Greene, Warner C -- Hoxie, James A -- Hunter, Eric -- Klein, George -- Korber, Bette -- Kuritzkes, Daniel R -- Lederman, Michael M -- Malim, Michael H -- Marx, Preston A -- McCune, Joseph M -- McMichael, Andrew -- Miller, Christopher -- Miller, Veronica -- Montagnier, Luc -- Montefiori, David C -- Moore, John P -- Nixon, Douglas F -- Overbaugh, Julie -- Pauza, C David -- Richman, Douglas D -- Saag, Michael S -- Sattentau, Quentin -- Schooley, Robert T -- Shattock, Robin -- Shaw, George M -- Stevenson, Mario -- Trkola, Alexandra -- Wainberg, Mark A -- Weiss, Robin A -- Wolinsky, Steven -- Zack, Jerome A -- New York, N.Y. -- Science. 2006 Nov 10;314(5801):924-5. Epub 2006 Oct 24.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17062652" target="_blank"〉PubMed〈/a〉
    Keywords: Child ; *Disease Outbreaks ; HIV Infections/*epidemiology/transmission ; Hiv-1 ; Health Personnel/*legislation & jurisprudence ; Humans ; Jurisprudence ; Libya/epidemiology ; *Prisoners ; *Social Justice
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2019
    Description: 〈p〉A versatile method for the design of colloidal crystals involves the use of DNA as a particle-directing ligand. With such systems, DNA-nanoparticle conjugates are considered programmable atom equivalents (PAEs), and design rules have been devised to engineer crystallization outcomes. This work shows that when reduced in size and DNA grafting density, PAEs behave as electron equivalents (EEs), roaming through and stabilizing the lattices defined by larger PAEs, as electrons do in metals in the classical picture. This discovery defines a new property of colloidal crystals—metallicity—that is characterized by the extent of EE delocalization and diffusion. As the number of strands increases or the temperature decreases, the EEs localize, which is structurally reminiscent of a metal-insulator transition. Colloidal crystal metallicity, therefore, provides new routes to metallic, intermetallic, and compound phases.〈/p〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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