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  • Articles  (3)
  • American Association for the Advancement of Science (AAAS)  (3)
  • 1
    Publication Date: 1979-05-11
    Description: The Galapagos mounds sea-floor hydrothermal system is at least 300,000 years old and once produced manganese-poor sediments, which nearly blanketed the area of the present mounds field. Present-day mound deposits are limited manganese-rich exposures, suggesting that the system has changed from rock-to water-dominated and has diminished in intensity with time.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Natland, J H -- Rosendahl, B -- Hekinian, R -- Dmitriev, Y -- Fodor, R V -- Goll, R M -- Hoffert, M -- Humphris, S E -- Mattey, D P -- Petersen, N -- Roggenthen, W -- Schrader, E L -- Srivastava, R K -- Warren, N -- New York, N.Y. -- Science. 1979 May 11;204(4393):613-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17839484" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 1982-06-11
    Description: The gamma-aminobutyric acid (GABA)-benzodiazepine receptor complex, which is composed of distinct proteins embedded in the neuronal plasma membrane, is important for several effects of benzodiazepines, including protection afforded against convulsions. During structural modification of ethyl beta-carboline-3-carboxylate an agent was discovered which has high affinity for brain benzodiazepine receptors but which is a potent convulsant. Also in contrast to benzodiazepines, this type of benzodiazepine receptor ligand favors benzodiazepine receptors in the non-GABA-stimulated conformation, which may explain the convulsive properties.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Braestrup, C -- Schmiechen, R -- Neef, G -- Nielsen, M -- Petersen, E N -- New York, N.Y. -- Science. 1982 Jun 11;216(4551):1241-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6281892" target="_blank"〉PubMed〈/a〉
    Keywords: Allosteric Regulation ; Animals ; Carbolines/*metabolism ; Cerebellum/metabolism ; *Convulsants ; Indoles/*metabolism ; Ligands ; Macromolecular Substances ; Neural Inhibition ; Rats ; Receptors, Cell Surface/*metabolism ; Receptors, Drug/classification/*metabolism ; Receptors, GABA-A
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 1982-04-16
    Description: The latest Mesozoic and earliest Tertiary sediments at Deep Sea Drilling Project site 524 provide an amplified record of environmental and biostratographic changes at the end of Cretaceous. Closely spaced samples, representing time intervals as short as 10(2) or 10(3) years, were analyzed for their bulk carbonate and trace-metal compositions, and for oxygen and carbon isotopic compositions. The data indicate that at the end of Cretaceous, when a high proportion of the ocean's planktic organisms were eliminated, an associated reduction in productivity led to a partial transfer of dissolved carbon dioxide from the oceans to the atmosphere. This resulted in a large increase of the atmospheric carbon dioxide during the next 50,000 years, which is believed to have caused a temperature rise revealed by the oxygen-isotope data. The lowermost Tertiary sediments at site 524 include fossils with Cretaceous affinities, which may include both reworked individuals and some forms that survived for a while after the catastrophe. Our data indicate that many of the Cretaceous pelagic organisms became extinct over a period of a few tens of thousands of years, and do not contradict the scenario of cometary impact as a cause of mass mortality in the oceans, as suggested by an iridium anomaly at the Cretaceous-Tertiary boundary.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hsu, K J -- He, Q -- McKenzie, J A -- Weissert, H -- Perch-Nielsen, K -- Oberhansli, H -- Kelts, K -- Labrecque, J -- Tauxe, L -- Krahenbuhl, U -- Percival, S F Jr -- Wright, R -- Karpoff, A M -- Petersen, N -- Tucker, P -- Poore, R Z -- Gombos, A M -- Pisciotto, K -- Carman, M F Jr -- Schreiber, E -- New York, N.Y. -- Science. 1982 Apr 16;216(4543):249-56.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17832725" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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