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  • Springer  (11)
  • American Association for the Advancement of Science (AAAS)  (5)
  • 1990-1994  (16)
  • 1940-1944
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  • 1
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract This study examines the impact of a new land-surface parameterization and a river routing scheme on the hydrology of the Amazon basin, as depicted by the NASA/Goddard Institute of Space Studies (GISS) global climate model (GCM). The more physically realistic land surface scheme introduces a vegetation canopy resistance and a six-layer soil system. The new routing scheme allows runoff to travel from a river's headwater to its mouth according to topography and other channel characteristics and improves the timing of the peak flow. River runoff is examined near the mouth of the Amazon and for all of its sub-basins. With the new land-surface parameterization, river run-off increases significantly and is consistent with that observed in most basins and at the mouth. The representation of the river hydrology in small basins is not as satisfactory as in larger basins. One positive impact of the new land-surface parameterization is that it produces more realistic evaporation over the Amazon basin, which was too high in the previous version of the GCM. The realistic depiction of evaporation also affects the thermal regime in the lower atmosphere in the Amazon. In fact, the lower evaporation in some portions of the basin reduces the cloudiness, increases the solar radiation reaching the ground, increases the net radiation at the surface, and warms the surface as compared to observations. Further GCM improvement is needed to obtain a better representation of rainfall processes.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract. This study examines the impact of a new land-surface parameterization and a river routing scheme on the hydrology of the Amazon basin, as depicted by the NASA/Goddard Institute of Space Studies (GISS) global climate model (GCM). The more physically realistic land surface scheme introduces a vegetation canopy resistance and a six-layer soil system. The new routing scheme allows runoff to travel from a river's headwater to its mouth according to topography and other channel characteristics and improves the timing of the peak flow. River runoff is examined near the mouth of the Amazon and for all of its sub-basins. With the new land-surface parameterization, river runoff increases significantly and is consistent with that observed in most basins and at the mouth. The representation of the river hydrology in small basins is not as satisfactory as in larger basins. One positive impact of the new land-surface parameterization is that it produces more realistic evaporation over the Amazon basin, which was too high in the previous version of the GCM. The realistic depiction of evaporation also affects the thermal regime in the lower atmosphere in the Amazon. In fact, the lower evaporation in some portions of the basin reduces the cloudiness, increases the solar radiation reaching the ground, increases the net radiation at the surface, and warms the surface as compared to observations. Further GCM improvement is needed to obtain a better representation of rainfall processes.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-6857
    Keywords: Coevolution ; tetracycline-resistance ; Escherichia coli ; pBR322 ; plasmid deletion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Under conditions where plasmid-carriage is deleterious to the cell, evolutionary changes may be expected which result in an attenuation of the deleterious effect of the plasmid. During long-term growth in glucose-limited continuous culture, initiated with a single clone of Escherichia coli containing a derivative of the plasmid pBR322, a structural change arose in the plasmid and predominated in the plasmid-containing sector of the population. This variant possessed a 2.25 kb deletion encompassing the tetracycline resistance operon as well as a region of about 1.5 kb upstream from this operon. Competition experiments involving strains carrying the plasmid with the spontancous deletion, and strains carrying plasmids with artificially constructed deletions, revealed that deletion of this region of the plasmid, involving loss of tetracycline resistance, resulted in an increment in fitness of between 10 and 20%. From the magnitude of the growth advantage, we conclude that the attenuation of the deleterious effect of the plasmid was mainly due to a reduction in the plasmid mediated interference in the metabolism of the cell caused by a deletion of the tetracycline resistance gene.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Evolutionary ecology 4 (1990), S. 276-276 
    ISSN: 1573-8477
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Evolutionary ecology 5 (1991), S. 219-219 
    ISSN: 1573-8477
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Evolutionary ecology 6 (1992), S. 95-96 
    ISSN: 1573-8477
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Evolutionary ecology 6 (1992), S. 90-93 
    ISSN: 1573-8477
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 8
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1990-07-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Beering, S C -- Rosenzweig, R M -- New York, N.Y. -- Science. 1990 Jul 6;249(4964):10-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17787601" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1990-03-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rosenzweig, R M -- New York, N.Y. -- Science. 1990 Mar 23;247(4949 Pt 1):1385.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2321003" target="_blank"〉PubMed〈/a〉
    Keywords: *National Institutes of Health (U.S.) ; Research Personnel/*economics ; Research Support as Topic/*organization & administration ; United States ; Universities/*economics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 1990-05-25
    Description: Multiple sclerosis (MS) may be an autoimmune disease mediated by T cells specific for a myelin protein. Investigations have demonstrated myelin basic protein (MBP)-reactive T cells that were activated in vivo in MS patients, suggesting that MBP may be a target antigen in MS. The variable (V) region of the T cell receptor (TCR) beta chain was examined among 83 T cell lines from both MS patients and healthy subjects that were reactive with the immunodominant region of human MBP (residues 84 to 102) or with a second immunodominant region of MBP (143 to 168). V beta 17 and to a lesser extent V beta 12 were frequently used in recognition of MBP(84-102) among different individuals. In contrast, V beta 17 was very infrequent among lines reactive with MBP (143-168). These data demonstrate shared TCR V beta gene usage for the recognition of immunodominant regions of the human autoantigen MBP. Such TCR structures may be used as targets for specific immunotherapy in MS.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wucherpfennig, K W -- Ota, K -- Endo, N -- Seidman, J G -- Rosenzweig, A -- Weiner, H L -- Hafler, D A -- 1 K11 HL 02228-01/HL/NHLBI NIH HHS/ -- NS 00981/NS/NINDS NIH HHS/ -- R01 NS 24247/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1990 May 25;248(4958):1016-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1693015" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Base Sequence ; Blotting, Southern ; Epitopes ; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor ; Humans ; Molecular Sequence Data ; Multiple Sclerosis/immunology ; Myelin Basic Protein/*immunology ; Polymerase Chain Reaction ; Receptors, Antigen, T-Cell/*genetics ; Receptors, Antigen, T-Cell, alpha-beta ; T-Lymphocytes/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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