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  • 1
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    Prostaglandin E1 inhibitis platelet aggregation by a pathway independent of adenosine 3',5'-monophosphate (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-04-14
    Description: Aggregation of human blood platelets induced by adenosine diphosphate or 1-epinephrine was inhibited when the platelets were suspended in plasma which had been previously exposed to an insolubilized omega-aminohexylagarose derivative of prostaglandin E1. This decrease of platelet aggregation was not accompanied by a change in the concentration of adenosine 3',5'-monophosphate (cyclic AMP) in platelets. The results demonstrate the existence of an alternative pathway independent of cyclic AMP for the inhibition of platelet aggregation by plasma.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sinha, A K -- Colman, R W -- New York, N.Y. -- Science. 1978 Apr 14;200(4338):202-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/204997" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Diphosphate/antagonists & inhibitors ; Cyclic AMP/*blood ; Epinephrine/antagonists & inhibitors ; Humans ; Plasma/physiology ; Platelet Aggregation/*drug effects ; Prostaglandins E, Synthetic/*pharmacology ; Sepharose/analogs & derivatives ; Solubility
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Prostacyclin stimulation of the activation of blood coagulation factor X by platelets (1986)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1986-01-24
    Description: When platelets were incubated with prostacyclin, prostaglandin E1, or prostaglandin D2 at concentrations insufficient to increase the level of adenosine 3',5'-monophosphate (cyclic AMP), coagulation factor X was activated by a platelet cysteine protease. Prostacyclin or prostaglandin E1 at higher concentrations increased the cyclic AMP level and inhibited the activation of factor X by platelets. Inhibition of platelet adenylate cyclase by 2',5'-dideoxyadenosine allowed the activation of the protease at higher concentrations of the autocoids. Prostaglandins A1, A2, B1, B2, E2, F2 alpha, 6-keto-prostaglandin F1 alpha, and thromboxane B2, which do not affect platelet cyclic AMP level, did not stimulate the protease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dutta-Roy, A K -- Ray, T K -- Sinha, A K -- New York, N.Y. -- Science. 1986 Jan 24;231(4736):385-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3001935" target="_blank"〉PubMed〈/a〉
    Keywords: Adenylyl Cyclases/metabolism ; Alprostadil/pharmacology ; Animals ; Blood Platelets/*drug effects/metabolism/physiology ; Cattle ; Cyclic AMP/metabolism ; Deoxyadenosines/analogs & derivatives/pharmacology ; *Dideoxyadenosine/*analogs & derivatives ; Epoprostenol/*pharmacology ; Factor X/*physiology ; Humans ; Peptide Hydrolases/metabolism ; Prostaglandin D2 ; Prostaglandins/pharmacology ; Prostaglandins D/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
    Electronic Resource
    Electronic Resource
    Spectral sum rule for time delay in R2 (1985)
    College Park, Md. : American Institute of Physics (AIP)
    Journal of Mathematical Physics 26 (1985), S. 2796-2802 
    Details
    ISSN: 1089-7658
    Source: AIP Digital Archive
    Topics: Mathematics , Physics
    Notes: A local spectral sum rule for nonrelativistic scattering in two dimensions is derived for the potential class v∈L4/3 (R2). The sum rule relates the integral over all scattering energies of the trace of the time-delay operator for a finite region Σ⊆R2 to the contributions in Σ of the pure point and singularly continuous spectra.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.526704
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  • 4
    Electronic Resource
    Electronic Resource
    Insulin secretion at high altitude in man (1986)
    Springer
    International journal of biometeorology 30 (1986), S. 231-238 
    Details
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract The effect of hypoxia on circulatory levels of insulin, its response to oral glucose administration (100 g) and changes in circadian rhythms of glucose as well as insulin were evaluated in euglycemic males at sea level (SL, 220 m) during their stay at high altitude (3500 m, SJ) and in high altitude natives (HAN). Basal glucose levels were not altered at high altitude but the rise in glucose (δ glucose) after glucose load was significantly higher in SJ and HAN (p〈0.01) as compared to SL values. An increase (p〈0.01) both in basal as well as glucose induced rise in insulin secretion (δ insulin) was observed at HA. The rise in insulin in SJ was significantly higher (p〈0.01) than in HAN. This elevation in glucose and insulin levels was also evident at different times of the day. The circadian rhythmicity of glucose as well as insulin was altered by the altitude stress. The findings of the study show a rise in insulin level at HA but the hyperglycemia in the face of hyper-insulinism require the presumption of a simultaneous and dispropotionate rise of insulin antagonistic hormones upsetting the effect of insulin on glucose metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02189466
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  • 5
    Electronic Resource
    Electronic Resource
    Comparative study of acetazolamide and spironolactone on body fluid compartments on induction to high altitude (1986)
    Springer
    International journal of biometeorology 30 (1986), S. 33-41 
    Details
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract Studies were conducted on 29 male healthy subjects having no previous experience of living at high altitude. These subjects were divided into three groups, i.e., subjects treated with placebo, acetazolamide and spironolactone. These subjects were first studied in Delhi. The drug schedule was started 24 hour prior to the airlift of these subjects to an altitude of 3,500 m and was continued for 48 hour after arrival at high altitude. Total body water, extra cellular water, plasma volume, blood electrolytes, pH, pO2, pCO2 and blood viscosity were determined on 3rd and 12th day of their stay at high altitude. Total body water, extra cellular water intracellular water and plasma volume decreased on high altitude exposure. There was a further slight decrease in these compartments with acetazolamide and spironolactone. It was also observed that spironolactone drives out more water from the extracellular compartment. Loss of plasma water was also confirmed by increased plasma osmolality. Increase in arterial blood pH was noticed on hypoxic exposure but the increase was found less in acetazolamide and spironolactone cases. This decrease in pH is expected to result in better oxygen delivery to the tissues at the low oxygen tension. It was also confirmed because blood pO2 increased in both the groups. No significant change in plasma electrolytes was observed in subjects of various groups. Blood viscosity slightly increased on exposure to high altitude. The degree of rise was found less in the group treated with spironolactone. This study suggests that both the drugs are likely to be beneficial in ameliorating/prevention of AMS syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02192056
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  • 6
    Electronic Resource
    Electronic Resource
    Possibility of a condensed phase of excitons because of phonon induced exciton-exciton pairing (1975)
    Springer
    The European physical journal 22 (1975), S. 173-176 
    Details
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In this paper we study the phonon-induced exciton-exciton interaction. It is found that the interaction can be attractive under certain conditions. Taking into account this attractive interaction, the pairing of excitons with opposite momenta is studied and the excitation spectrum determined. The results are similar to a system of bosons. There appears to be some possibility of superfluid behaviour.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01322361
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  • 7
    Electronic Resource
    Electronic Resource
    Radio frequency emission in electron beam-plasma and beam-beam interaction (1978)
    Springer
    Astrophysics and space science 53 (1978), S. 13-19 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A linear excitation of electromagnetic modes at frequencies $$ \simeq (n + \tfrac{1}{2})\omega _{ce} $$ , in a plasma through which two electron beams are contra-streaming along the magnetic field is investigated. This may be a source of the observed $$\tfrac{3}{2}\omega _{ce} $$ emissions at auroral latitudes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00645900
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  • 8
    Electronic Resource
    Electronic Resource
    The superfluid as a source of all interactions (1978)
    Springer
    Foundations of physics 8 (1978), S. 823-831 
    Details
    ISSN: 1572-9516
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The superfluid state of fermion-antifermion fields developed in our previous papers is generalized to include higher orbital and spin states. In addition to single-particle excitations, the system is capable of having real and virtual bound or quasibound composite excitations which are akin to bosons of spinJ P equal to0 −, 1−, 2+, etc. These pseudoscalar, vector, and tensor bosons can be massive or massless and provide the vehicles for strong, electromagnetic, weak, and gravitational interactions. The concept that the basic (unmanifest) fermion-antifermion interaction can lead to a multiplicity of manifest interactions seems to provide a basis for a unified field theory.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00715056
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  • 9
    Electronic Resource
    Electronic Resource
    Aether as a superfluid state of particle-antiparticle pairs (1976)
    Springer
    Foundations of physics 6 (1976), S. 65-70 
    Details
    ISSN: 1572-9516
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A new model for the aether is suggested according to which it is a superfluid state of fermion and antifermion pairs, describable by a macroscopic wave function. The vacuum state of this superfluid pervades the entire universe and may account for the missing matter. The visible matter in the universe appears as excitations from the underlying superfluid vacuum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00708664
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  • 10
    Electronic Resource
    Electronic Resource
    The superfluid vacuum state, time-varying cosmological constant, and nonsingular cosmological models (1976)
    Springer
    Foundations of physics 6 (1976), S. 717-726 
    Details
    ISSN: 1572-9516
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Some cosmological consequences of the superfluid vacuum state developed previously by the authors are discussed, particularly with regard to the initial stages of the universe. The transition temperature of the hadronic superfluid (superfluid during the hadron era) is estimated to be 10 13 K, which is the same as the Hagedorn temperature, giving a physical basis of the thermodynamic bootstrap model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00708950
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