Publication Date:
1983-09-09
Description:
Along with homosexual men, Haitians, and intravenous drug abusers, hemophiliacs are at high risk of contracting acquired immunodeficiency syndrome (AIDS). An earlier study revealed that 36 percent of a group of the AIDS patients had antibodies to cell membrane antigens associated with the human T-cell leukemia virus (HTLV-MA), whereas only 1.2 percent of matched asymptomatic homosexual controls had these antibodies. In the present experiments, serum samples from 172 asymptomatic hemophiliacs were examined for the presence of antibodies to HTLV-MA. Such antibodies were detected in 5 to 19 percent of the hemophiliacs examined from four geographical locations, but in only 1 percent or less of laboratory workers, normal blood donors, donors on hemodialysis, or donors with chronic active hepatitis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Essex, M -- McLane, M F -- Lee, T H -- Tachibana, N -- Mullins, J I -- Kreiss, J -- Kasper, C K -- Poon, M C -- Landay, A -- Stein, S F -- Francis, D P -- Cabradilla, C -- Lawrence, D N -- Evatt, B L -- 2-T32-CA09031/CA/NCI NIH HHS/ -- CA 18216/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 9;221(4615):1061-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6603659" target="_blank"〉PubMed〈/a〉
Keywords:
Antibodies, Viral/*analysis
;
Antigens, Surface/immunology
;
Antigens, Viral/*immunology
;
Hemophilia A/immunology/*microbiology
;
Humans
;
Leukemia/*microbiology
;
Retroviridae/*immunology
;
*T-Lymphocytes
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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