ISSN:
1435-1536
Keywords:
Reversed micelle
;
oligomer of L-lysine
;
circular dichroism measurement
;
conformational transition
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Abstract The effect of the chain length on the conformation of oligo-L-lysines (Lys-n, n= 9, 12 and 15) was examined in the reversed micelles of bis(2-ethylhexyl)sodium sulfosuccinate (AOT) in octane by the circular dichroism (CD) measurements. These oligomers seem to take aβ-structure in these systems. The structure-inducing effect of the reversed micelles is enhanced as the molar ratio of water to AOT (w0=[H2O]/[AOT]) becomes smaller. On the other hand, in the aqueous solutions the oligomers having 12 and 15 residues show the conformational transition from random coil toα-helical structure by the addition of AOT, but the short oligomer of 9 residues does not show such a conformational transition.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01469630
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