ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] The inhibitor used in these studies is (R)-2-dodecanoyl-amino-1-hexanol-phosphoglycol (Fig. 1). This inhibitor binds by over three orders of magnitude more strongly than the sub-strate (R)-1 ^-di-dodecanoyl-glycerol-S-phosphocholine11 to phospholipase A2. A porcine phospholipase A2 mutant obtained ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/347689a0
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