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  • 1
    Publication Date: 1993-12-24
    Description: The elongated proteins of the spectrin family (dystrophin, alpha-actinin, and spectrin) contain tandemly repeated segments and form resilient cellular meshworks by cross-linking actin filaments. The structure of one of the repetitive segments of alpha-spectrin was determined at a 1.8 angstrom resolution. A segment consists of a three-helix bundle. A model of the interface between two tandem segments suggests that hydrophobic interactions between segments may constrain intersegment flexibility. The helix side chain interactions explain how mutations that are known to produce hemolytic anemias disrupt spectrin associations that sustain the integrity of the erythrocyte membrane.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yan, Y -- Winograd, E -- Viel, A -- Cronin, T -- Harrison, S C -- Branton, D -- CA 13202/CA/NCI NIH HHS/ -- HL 17411/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1993 Dec 24;262(5142):2027-30.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biochemistry, Harvard University, Cambridge, MA 02138.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8266097" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Crystallization ; Drosophila ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Spectrin/*chemistry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 116 (1994), S. 9464-9470 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 129 (Jan. 1993), p. 155-164 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 150-151 (Jan. 1994), p. 323-334 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Numerische Mathematik 65 (1993), S. 423-433 
    ISSN: 0945-3245
    Keywords: 65R20
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary Here we study the piecewise constant collocation method using mesh grading to solve Symm's integral equation on [−1, 1]. We give a mesh grading for which this method achieves the optimal order of convergence even though the piecewise constant Galerkin method with the same mesh grading does not. Some numerical results are given.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 94 (1991), S. 997-1005 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A microscopic theory for ultrafast coherent Raman spectroscopy of polyatomic molecules in condensed phases is developed. For off resonant excitation, an effective Hamiltonian that controls the molecular dynamics in a Raman process is derived. The limitations of the driven oscillator model are clarified, and generalized equations of motion, which hold for resonant and off resonant excitation, are derived. Spectral selectivity using pulse shaping is discussed.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 93 (1990), S. 4501-4509 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Dynamic light scattering from highly concentrated colloidal systems with a narrow distribution of particle sizes can be interpreted in terms of the sum of two independent modes due, respectively, to collective diffusion and polydispersity fluctuations; a general formalism has been presented for calculating the relative mode amplitudes for hard spheres in the Percus–Yevick approximation [Pusey, Fijnaut, and Vrij, J. Chem. Phys. 77, 4270(1982)]. This work extends the relative mode amplitude calculation to the general case where optical (i.e., refractive index) and size polydispersity are completely coupled such as in water-in-oil microemulsions. To develop the theory a concentric core-shell hard sphere model is adopted, in which particles possess a continuous variation in the core sizes but have constant shell thickness, thus giving rise to a distribution in the particle refractive indices. A new "measured'' static structure factor SM(0) is derived, and applied to the calculation for the relative amplitude of the slow mode, A2/(A1+A2), as a function of solvent refractive index n0. A strong enhancement of the slow mode is predicted as the optical matching point is approached. The theory also shows that the dependence of A2/(A1+A2) on n0 is very sensitive to the extent of polydispersity, but rather insensitive to the distribution function used. Neglect of the nonuniformity in particle refractive index can cause a substantial overestimate of the size polydispersity. We have used our extended treatment to interpret the dynamic light scattering data from concentrated water-in-oil microemulsions formed from H2O, AOT, and apolar solvents using solvent composition to control the contrast in refractive index. It is found that the AOT-stabilized water microemulsion droplets have a size polydispersity of about 6.5%, which is smaller than previously thought.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 98 (1994), S. 3809-3817 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 104 (1991), S. 0 
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: We analyse statistically the long-term properties of several instrumental earthquake catalogues. Complete catalogues exhibit both short- and long-term clustering for earthquakes of all depth ranges. After accounting for the effect of short-term clustering, we find that in residual (declustered) catalogues, long-term clustering, not periodicity, characterizes the occurrence of all earthquakes-shallow, intermediate, and deep. the degree of clustering in residual catalogues is the same for earthquakes in different depth ranges. Circumstantial evidence indicates that the long-term variation of seismicity is governed by a power-law temporal distribution; as in short-term clustering, it is scale invariant. the fractal dimension of an earthquake set on the time axis is of the order of 0.8–0.9. Therefore, mainshock occurrence is closer to a stationary Poisson process than standard aftershock sequences of shallow earthquakes.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 5940-5940 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effects of a magnetic underlayer on the magnetic behavior of overlayer/underlayer combinations were investigated. Permalloy underlayers of 100 nm thickness and composition 82% Ni-18% Fe by weight were sputter deposited on 3-in.-diam Si substrates. Magnetic orientations of the underlayers were set at 0°, 45°, and 90° with respect to the orientation of a subsequently plated Permalloy (79%Ni-21%Fe overlayer. Several film combinations were generated on each of the various underlayer configurations with plated thicknesses ranging from 0.1 to 2.0 μm. Spatial maps of magnetic orientation and Hk for underlayers and underlayer/overlayer combinations were collected using a modified Kerr BH imager (Kerr BHI) designed from Gudeman.1 The maps covered a 5 cm×5 cm square region with 5 mm spacing between points. Comparison of the maps before and after plating shows a partial reduction in the measured Hk values for film systems with large underlayer/overlayer orientation differences. A uniform decline in the effect of the underlayer to the overall orientation direction as film thicknesses increase was also observed.
    Type of Medium: Electronic Resource
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