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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 3 (2000), S. 403-412 
    ISSN: 1292-895X
    Keywords: PACS. 87.16.-b Subcellular structure and processes [:AND:] 87.19.-j Properties of higher organisms - 47.55.Dz Drops and bubbles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: We study theoretically vesicle locomotion due to haptotaxis. Haptotaxis is referred to motion induced by an adhesion gradient on a substrate. The problem is solved within a local approximation where a Rayleigh-type dissipation is adopted. The dynamical model is akin to the Rousse model for polymers. An invariant formulation is used to solve a dynamical model which includes a kind of dissipation due to bond breaking/restoring with the substrate. For a stationary situation where the vesicle acquires a constant drift velocity, we formulate the propulsion problem in terms of a nonlinear eigenvalue (the a priori unknown drift velocity) one of Barenblat-Zeldovitch type. A counting argument shows that the velocity belongs to a discrete set. For a relatively tense vesicle, we provide an analytical expression for the drift velocity as a function of relevant parameters. We find good agreement with the full numerical solution. Despite the oversimplification of the model it allows the identification of a relevant quantity, namely the adhesion length, which turns out to be crucial also in the nonlocal model in the presence of hydrodynamics, a situation on which we have recently reported (I. Cantat and C. Misbah, Phys. Rev. Lett. 83, 235 (1999)) and which constitutes the subject of a forthcoming extensive study.
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  • 2
    ISSN: 1420-9071
    Keywords: Key words.klotho; endothelial function; nitric oxide production; hypertension; renal failure; cytokine.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The human aging process is associated with vascular endothelial dysfunction. However, humoral factors which might protect against endothelial dysfucntion during aging have not yet been identified. We recently identified the klotho gene as a possible regulator of human aging. In the present study using the klotho-deficient heterozygous mouse, we examined whether the Klotho protein is a humoral factor protecting against endothelial dysfunction. We further cloned rat klotho cDNA and investigated whether klotho mRNA expression in rat kidney is altered under pathological conditions such as hypertension, hyperlipidemia, renal failure, and inflammatory stress. The Klotho protein itself, or its metabolites, promotes endothelial NO production in aorta as well as arterioles, and klotho mRNA in kidney is downregulated under sustained circulatory stress.
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 87 (2000), S. 6064-6066 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Optimum junction resistance and minimum tunnel magnetoresistance (TMR) ratio required for high density and high performance magnetoresistive random access memory (MRAM) devices with a TMR cell plus field effect transistor (FET) switch architecture are discussed by taking into account the variation of FET resistance causing noise. This implies that a TMR ratio over 25% at a 400 mV bias voltage and junction resistance of several tens of kilo-ohms for TMR cells are required with a signal voltage of 30 mV and a sense current of 10 μA, which leads to about 10 ns read time. This large magnetoresistance ratio at the elevated bias voltage requires low bias voltage dependence of TMR for the MRAM devices. In order to try to meet this requirement, double tunnel junctions were fabricated which possess the central ferromagnetic layer consisting of a thin discontinuous layer of hard ferromagnetic Co80Pt20 nanoparticles and insulating Al2O3 prepared by alternate sputtering of Co80Pt20 and Al2O3 targets. The maximum TMR obtained was 20.5% at room temperature for FeCo top and bottom electrodes without annealing. Bias voltage dependence of the (NiFe/CoFe)/1.5 nm Al2O3/discontinuous CoPt/2.6 nm Al2O3/(CoFe/NiFe) double tunnel junctions were revealed to be small compared to that of single junctions, the barrier of which was also fabricated by sputtering of an Al2O3 target. © 2000 American Institute of Physics.
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 87 (2000), S. 1276-1279 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Ag and Cu ions were implanted sequentially into LiNbO3 at different ratios of Cu and Ag ions, and in two different energy regimes: kiloelectron volt and megaelectron volt. Optical absorption spectra were measured in the visible region at each stage in the process of annealing the sample. For the samples implanted sequentially with Ag and Cu ions at the low energy of 20 keV, only one peak appeared between 430 and 630 nm, the position of which depended on the ratios of Ag and Cu ions. For the samples implanted at high energies of 3 or 4.2 MeV, two large and distinct absorption peaks were observed at 480 and 590 nm. When the samples were heated to high temperatures, the peak at 480 nm ascribed to colloids of Ag shifted gradually to longer wavelengths and reached 530 nm, whereas the red shift of the peak ascribed to colloids of Cu was approximately 15 nm. Cu atoms diffuse out of the doubly implanted layer faster and at lower temperatures compared with Ag, even when Cu ions were implanted deeper than the Ag. © 2000 American Institute of Physics.
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 71 (2000), S. 3024-3030 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A new-type analyzer for measurement of energetic neutral atoms (ENAs) in an energy range of 4–40 keV is described. Incoming ENAs are ionized by electron stripping at passage of an ultrathin carbon foil. After post-acceleration (by 3 kV), the particles are guided to a time-of-flight (TOF) section over a wide energy-per-charge bandwidth by means of electrostatic deflection without any potential sweeping for electrodes. Then, their velocity is measured by the TOF technique, with which species can also be identified, because the particle energies are limited to a certain range by the electrostatic deflector and acceleration upon entering the TOF section. A unique feature in the present analyzer is in the rejection method of extreme ultraviolet (EUV) contamination. In contrast to conventional usage of serrated electrodes for EUV attenuation, one of the electrostatic deflection plates is machined to be so flat that EUV photons are guided to a photon trap regardless of wavelength. The TOF device can also be used in a coincidence mode for noise suppression. The present instrument was flown on a sounding rocket, and has successfully measured ENAs precipitating into the low-latitude upper atmosphere from the magnetosphere. © 2000 American Institute of Physics.
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  • 6
    ISSN: 1439-5444
    Keywords: Key words Tetranychidae ; Schizotetranychus miscanthi ; Geographic variation ; Cline ; Antagonism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The intensity of male-to-male aggression, when evaluated in the laboratory, varies geographically in a subsocial spider mite, Schizotetranychus miscanthi Saito. This species includes two types of populations showing different clinal trends in aggression. We examined the relationships between the intensity of male aggression and the distribution patterns of individuals within nests for 22 field populations of the "low-aggression group." The intensity of male aggression was negatively correlated with the index of male aggregation across nests, which strongly suggests that aggression measured under experimental conditions is actually reflected in the interaction between males within nests in the field. The intensity of male aggression was also negatively correlated with the mean number of males per nest, suggesting that mortal fight between males, observed in the laboratory, actually occurs in the field.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' journal of analytical chemistry 368 (2000), S. 641-643 
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A novel “fiber-in-tube” configuration has been applied to the extraction tube of solid phase microextraction (SPME), and the direct coupling of the extraction process to liquid chromatography (LC) has been accomplished for the analysis of n-butylphthalate in wastewater. By using this fiber-in-tube SPME/LC system the preconcentration factor for the phthalate was about 160 with 20 min extraction and no interference peak was observed in the chromatogram. The results also showed the potential applications of this fiber-in-tube SPME/LC for the analysis of sub-ppb level (i.e., lower than 1 ng/mL) of various organic analytes in aqueous sample matrix without a large solvent consumption during the preconcentration process.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 396-402 (July 2002), p. 309-314 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 426-432 (Aug. 2003), p. 1059-1064 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 426-432 (Aug. 2003), p. 3867-3872 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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