ISSN:
1434-193X
Keywords:
Supramolecular chemistry
;
Domino reactions
;
Oligopyridines
;
Dihydropyridines
;
Mannich bases
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
---An annelation reaction is presented in which 1,3-cyclohexanedione (1) and Mannich bases 6a,b are used for the preparation of functionalized bipyridines 12a, 13a, 14a and dihydropyridine derivatives 10b, 11b. All these products possess a keto group which will allow further transformations. The same concept was applied for the synthesis of the S-shaped terpyridine 25. The reaction of the Mannich base 21 with 1,3-cyclohexanedione yielded the heptacyclic terpyridine 22, which is a key intermediate for the synthesis of torands and other tridentate clefts. The ketone 12a was used for the synthesis of the quaterpyridine 26.
Type of Medium:
Electronic Resource
Permalink
