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  • 2020-2024  (131)
  • 1965-1969  (594)
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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Hematology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Hematology.
    Description / Table of Contents: Live Donors of Tissue -- Deceased Tissue Donors -- Banking and Use of Umbilical Cord Blood -- Ocular tissue banking -- Banking of Heart Valves -- Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Storage, Processing and Preservation -- Cryopreservation in tissue banking -- Sterilisation by Irradiation -- Screening the tissue donor for infectious agents -- Contamination in the Tissue Way -- Establishing a Quality System in a Tissue Establishment -- IT System requirements for Tissue and Cell Banking -- Ethical and Regulatory Aspects of Cell and Tissue Banking -- Human embryonic stem cell banking for clinical applications – 20 years from their isolation.
    Abstract: It has been 10 years since the first edition of ‘Essentials of Tissue Banking’ has been published. There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex. The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissue establishments.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 48 illus., 28 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030716219
    DDC: 610.72
    Language: English
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  • 2
    Series available for loan
    Series available for loan
    Washington, DC : United States Gov. Print. Off.
    Associated volumes
    Call number: SR 90.0002(272-G)
    In: Professional paper
    Type of Medium: Series available for loan
    Pages: IV S., S. 137-150
    Series Statement: U.S. Geological Survey professional paper 272-G
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 3
    Monograph available for loan
    Monograph available for loan
    New York, NY [u.a.] : McGraw-Hill
    Call number: G 5600 ; 11970 ; 10131
    Type of Medium: Monograph available for loan
    Pages: XI, 403 S. : graph. Darst., Kt.
    Series Statement: MacGraw-Hill international series in the earth and planetary sciences
    Language: English
    Location: Upper compact magazine
    Location: Upper compact magazine
    Location: Upper compact magazine
    Branch Library: GFZ Library
    Branch Library: GFZ Library
    Branch Library: GFZ Library
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  • 4
    Publication Date: 2023-07-06
    Description: The Tibetan Plateau, also known as the “Water Tower of Asia” because of its function as a water storage and supply region, responds dramatically to modern climate changes. Paleoecological shifts inferred from lake sediment archives provide essential insights into past climate changes, and the processes that drove those shifts. This is especially true for studies of lakes in endorheic basins on the Tibetan Plateau, where lake level is regulated predominantly by Monsoon intensity. Such water bodies provide excellent opportunities to reconstruct past changes in humidity. Most paleolimnological investigations of lakes on the Tibetan Plateau, however, have involved the study of a single sediment core, making it difficult to discern between changes caused by local events and those caused by lake-wide or regional processes. Here we present results from a paleolimnological study of Lake Taro Co, a currently closed-basin lake in Central Tibet. We compared a sediment record from the central part of the lake to a record from the near-shore area, and present results of sedimentological and bioindicator (chironomid, diatom, pollen) analyses from both records. Results show three periods of lake-wide ecosystem change (〉 ca. 5250, 5250–2250 and 〈 since about 2250 cal year BP), which reflect a continuous drying trend throughout the Middle and Late Holocene. In addition to this lake-wide trend, we identified two local events in the sediment core from the southeastern, nearshore site. These include (1) a hiatus between 12,400 and 5400 cal year BP and (2) an 1800-year period of distinct paleoenvironmental conditions (5400–3600 cal year BP). We hypothesize that both events were caused by relocation of a river in the southeast sector of the lake’s catchment. We propose that the first relocation caused an erosion event that removed sediment, thereby producing the hiatus. During the following 1800 years, the core site may have been located on the river delta, before another river relocation at 3600 cal year BP established the modern prodelta situation. Our study demonstrates the value of using multiple sediment cores from a lake, to better identify processes that control widespread versus local events.
    Description: Bundesministerium für Bildung und Forschung http://dx.doi.org/10.13039/501100002347
    Description: Fellowships for Young International Scientists http://dx.doi.org/10.13039/501100010895
    Description: NSFC Research Fund for International Young Scientists (CN)
    Description: Deutsche Forschungsgemeinschaft (DFG) (DE)
    Description: National Natural Science Foundation of China http://dx.doi.org/10.13039/501100001809
    Description: Technische Universität Braunschweig (1042)
    Keywords: ddc:551 ; Monsoon ; Chironomidae ; Diatoms ; Geochemistry ; XRF ; Paleolimnology
    Language: English
    Type: doc-type:article
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  • 5
    Publication Date: 2023-11-18
    Description: Cyclostratigraphy and astrochronology are now at the forefront of geologic timekeeping. While this technique heavily relies on the accuracy of astronomical calculations, solar system chaos limits how far back astronomical calculations can be performed with confidence. High‐resolution paleoclimate records with Milankovitch imprints now allow reversing the traditional cyclostratigraphic approach: Middle Eocene drift sediments from Newfoundland Ridge are well‐suited for this purpose, due to high sedimentation rates and distinct lithological cycles. Per contra, the stratigraphies of Integrated Ocean Drilling Program Sites U1408–U1410 are highly complex with several hiatuses. Here, we built a two‐site composite and constructed a conservative age‐depth model to provide a reliable chronology for this rhythmic, highly resolved (〈1 kyr) sedimentary archive. Astronomical components (g‐terms and precession constant) are extracted from proxy time‐series using two different techniques, producing consistent results. We find astronomical frequencies up to 4% lower than reported in astronomical solution La04. This solution, however, was smoothed over 20‐Myr intervals, and our results therefore provide constraints on g‐term variability on shorter, million‐year timescales. We also report first evidence that the g〈sub〉4〈/sub〉–g〈sub〉3〈/sub〉 “grand eccentricity cycle” may have had a 1.2‐Myr period around 41 Ma, contrary to its 2.4‐Myr periodicity today. Our median precession constant estimate (51.28 ± 0.56″/year) confirms earlier indicators of a relatively low rate of tidal dissipation in the Paleogene. Newfoundland Ridge drift sediments thus enable a reliable reconstruction of astronomical components at the limit of validity of current astronomical calculations, extracted from geologic data, providing a new target for the next generation of astronomical calculations.
    Description: Plain Language Summary: The traditional cyclostratigraphic approach is to align and correlate a geologic depth‐series with an astronomical solution. However, the chaotic nature of the Solar System prevents astronomers from precisely calculating planetary motions beyond 40–50 million years ago. This in turn limits the options for geologists to use the resulting oscillations in Earth's climate system as a metronome for determining geologic time. In this study, we reversed the cyclostratigraphic approach and used the highly rhythmical sedimentary deposits from Newfoundland Ridge (North Atlantic) to back‐calculate planetary motions at ∼41 million years ago. The superior quality of the Newfoundland Ridge geoarchive originates from the combination of relatively high sedimentation rates (∼4 cm/kyr) and the time‐continuous character of our two‐site composite record between 39.5 and 42.8 million years ago. In this work, we had to first overcome considerable challenges in reconstructing the timing of sediment deposition, which we did with highly resolved geochemical measurements from two sites. We then were able to extract information on the Earth's planetary motion and on the Earth‐Moon interactions. These astronomical reconstructions based on geological data can now be used by astronomers to describe the evolution of the solar system further back in time than was previously possible.
    Description: Key Points: A new precession‐based cyclostratigraphy for the middle Eocene intervals of IODP Sites U1408 and U1410. Variability in astronomical fundamental frequencies (g‐terms) on million‐year timescales is larger than previously assumed. Our precession constant estimate for 41 Ma (51.28 ± 0.56″/year) confirms earlier indicators of slower tidal dissipation in the Paleogene.
    Description: National Science Foundation http://dx.doi.org/10.13039/100000001
    Description: University of California http://dx.doi.org/10.13039/100005595
    Description: Belgian American Educational Foundation http://dx.doi.org/10.13039/100001491
    Description: https://paloz.marum.de/AstroComputation/index.html
    Description: https://paloz.marum.de/confluence/display/ESPUBLIC/NAFF
    Keywords: ddc:551 ; North Atlantic ; Eocene ; cyclostratigraphy ; astrochronology
    Language: English
    Type: doc-type:article
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  • 6
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sterile culture nitrates from Penicillium stoloniferum were added to cells (Earle's L strain) previously grown for 24 h in Eagle's medium1 on microscope cover glasses, in doubling dilutions from 1 : 10 to 1 : 640. After a further 24 h, mitotic figures were absent at all dilutions down to 1 : 320. ...
    Type of Medium: Electronic Resource
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  • 7
    Publication Date: 1969-08-01
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
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  • 8
    Publication Date: 1969-01-01
    Print ISSN: 0040-4020
    Electronic ISSN: 1464-5416
    Topics: Chemistry and Pharmacology
    Published by Elsevier
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  • 9
    Publication Date: 2023-03-14
    Description: Copious amounts of organic carbon are stored for long periods of time in deep continental groundwaters. Little is known about its composition and cycling, mainly due to the difficulties in obtaining sample material. Cool fracture waters of different origins can be obtained under clean conditions at Äspö Hard Rock Laboratory (Äspö HRL, Sweden), operated by the Swedish Nuclear Fuel and Waste Management Company (SKB). We sampled groundwater from different depth (171 to 507 meter below sea level) in the bedrock fractures in November 2018 and March-April 2019. We assessed water chemistry and dissolved organic matter composition via stable carbon isotopic and molecular-formula level analysis in recent Baltic Sea-influenced to old saline fracture waters in the granitic Fennoscandian shield. Physicochemical parameters, major ions, water isotopic compositions (δ18O and δD), total nitrogen as well as dissolved organic matter concentration and stable isotopic composition were obtained for unfiltered groundwater samples from different boreholes.
    Keywords: aquifer; BalticSea_Äspö; BalticSea_Kalmar; Calcium; Carbon, organic, dissolved; Carbon, organic, dissolved, standard deviation; Carbon-14, modern, dissolved inorganic carbon; Carbon-14, modern, dissolved organic carbon; Chlorine; Conductivity; DATE/TIME; Elevation of event; Event label; Extraction efficiency; FT-ICR-MS; groundwater; HA2780A_1; Iron; Iron, total; Iron 2+; KA1755A_3; KA2051A01_5; KA2511A_5; KA2862A_1; KA2865A01_1; KA3105A_3; KA3385A_1; KA3510A_2; KA3600F_2; Latitude of event; Longitude of event; Magnesium; Manganese; Nitrogen, total dissolved; Nitrogen, total dissolved, standard deviation; Nitrogen in ammonium; Nitrogen in nitrate; Nitrogen in nitrite; pH; Phosphorus in phosphate; Potassium; SA1229A_1; SA1730A_1; SA2600A_1; Sodium; Sulfide in hydrogen sulfide; Sulfur in sulfate; Sweden; Temperature, water; Type; δ13C, dissolved inorganic carbon; δ13C, dissolved organic carbon; δ18O, water; δ Deuterium, water
    Type: Dataset
    Format: text/tab-separated-values, 1050 data points
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  • 10
    Publication Date: 2023-01-30
    Description: Copious amounts of organic carbon are stored for long periods of time in deep continental groundwaters. Little is known about its composition and cycling, mainly due to the difficulties in obtaining sample material. Cool fracture waters of different origins can be obtained under clean conditions at Äspö Hard Rock Laboratory (Äspö HRL, Sweden), operated by the Swedish Nuclear Fuel and Waste Management Company (SKB). We sampled groundwater from different depth (171 to 507 meter below sea level) in the bedrock fractures in November 2018 and March-April 2019. We assessed water chemistry and dissolved organic matter composition via stable carbon isotopic and molecular-formula level analysis in recent Baltic Sea-influenced to old saline fracture waters in the granitic Fennoscandian shield. Molecular-level dissolved organic matter composition via Fourier-transform ion cyclotron resonance mass spectrometry using electrospray ionization in negative mode (FT-ICR-MS, 15 T Bruker Solarix) was done on solid-phase extracted (PPL) DOM extracts. Relative peak intensities from FT-ICR-MS with molecular formula attributions, elemental ratios and compound group classification of the final dataset are given. ICBM-Ocean was used for processing of FT-ICR mass spectra and formula attribution (Merder et al., 2020; doi:10.1021/acs.analchem.9b05659).
    Keywords: aquifer; Aromaticity index, modified; BalticSea_Äspö; BalticSea_Kalmar; Double bond equivalent; Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS, 15 T Bruker Solarix); FT-ICR-MS; groundwater; HA2780A_1; Hydrogen/Carbon ratio; KA1755A_3; KA2051A01_5; KA2511A_5; KA2862A_1; KA2865A01_1; KA3105A_3; KA3385A_1; KA3510A_2; KA3600F_2; Mass of molecular formulas; Molecular formula; Nitrogen/Carbon ratio; Oxygen/Carbon ratio; Peak intensity; Phosphorus/Carbon ratio; Presence/absence; SA1229A_1; SA1730A_1; SA2600A_1; Sulfur/Carbon ratio; Sweden
    Type: Dataset
    Format: text/tab-separated-values, 814592 data points
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