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  • 1
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    The Second Life of Natural Killer (NK) Cells (2021)
    Frontiers Media SA
    Details
    Publication Date: 2023-12-21
    Description: Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of “Innate lymphoid cells” (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to microbial and cell stress stimuli, thus playing a central role in the defense against pathogen infection, in tumor surveillance and in regulating immune homeostasis. Despite these established concepts, our understanding of the complexity of NK cells, also in view of their developmental and functional relationship with other ILC subsets, is only recently emerging. This Research Topic highlights the recent advances in NK cell (and ILC) research in human and mouse from basic research to clinical applications.
    Keywords: R5-920 ; RC581-607 ; natural killer cells ; ILC ; NK cells ; immune therapy ; viral infection ; NK cell education ; immunotherapy ; MHC-I ; cancer ; immune regulation ; adaptive immunity ; bic Book Industry Communication::M Medicine
    Language: English
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  • 2
    Electronic Resource
    Electronic Resource
    Structural alterations of chloroplasts induced by virus inAhutilon striatum V. Thompson (1965)
    Springer
    Protoplasma 60 (1965), S. 426-434 
    Details
    ISSN: 1615-6102
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01247890
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Formation of gigantic mitochondria in hypoxic isolated perfused rat hearts (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 763-764 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Herzen gesunder, erwachsener Ratten wurden mit Krebs-Henseleit-Bikarbonatlösung durchströmt (95% O2∶5% CO2). Bei künstlich herbeigeführter Hypoxie (95% N2∶5% CO2) erschienen die Herzmitochondrien innerhalb von 7 min bedeutend vergrössert und zu 25% miteinander verschmolzen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01897616
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  • 4
    Electronic Resource
    Electronic Resource
    Membrane-bound microtubular and crystalline structures in endothelial cells of normal canine aorta (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 301-302 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Es wurden 2 Typen von membrangebundenen Zytoplasmastrukturen im vorliegenden Endothel von normalen Hundeaorten gefunden. Teilweise handelt es sich um rauhe parallele Mikrotubuli (240 Å) und um kristallines Material mit einer Periode von 130–180 Å. Die funktionelle Korrelation von Mikrotubuli und den kristallinen Strukturen ist noch unklar.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02034408
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  • 5
    Electronic Resource
    Electronic Resource
    Origin of Round-body Structures in the Orgueil Meteorite (1967)
    [s.l.] : Nature Publishing Group
    Nature 216 (1967), S. 252-253 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1-7. Electron micrographs of ultra-thin sections of the Orgueil meteorite showing the round structures. Small pieces of the Orgueil meteorite (from the Smith -sonian Institution, Washington, DC, by courtesy of Dr G. Claus, Long Island University) were embedded in 'Epon' resin to facilitate ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/216252a0
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  • 6
    Electronic Resource
    Electronic Resource
    An electron microscope study of sunflower crown gall tumor (1967)
    Springer
    Protoplasma 64 (1967), S. 195-200 
    Details
    ISSN: 1615-6102
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The inception and developmental phases of sunflower (Helianthus annuus) crown gall tumor growth induced byAgrobacterium tumefaciens were studied submicroscopically. Bacteria were found only in the inception phase. Chloroplasts from tumor cells of both phases showed several kinds of structural variation. Other cytoplasmic organelles remained more or less normal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01250387
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  • 7
    Electronic Resource
    Electronic Resource
    Subcellular alterations in cortisone treated rat lungs (1965)
    Springer
    Cell & tissue research 67 (1965), S. 718-722 
    Details
    ISSN: 1432-0878
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Lungs from cortisone treated rats were examined under the electron microscope. Major alterations appeared in the mitochondria; changes in the endoplasmatic reticulum and basement membranes were also observed. Isolated features noticed were extracellular and intracellular lattice structures, crystalloid formation, swelling of the Golgi apparatus and nuclear damage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00340333
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  • 8
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    Mechanism of multidecadal oscillation in north Atlantic ocean and implications for Asian climate (2023)
    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Details
    Publication Date: 2023-04-17
    Description: The North Atlantic sea surface temperature multidecadal oscillation, or AMO, has a substantial impact on both the global and local climate. The authors suggest a delayed oscillator model of interdecadal sea-air coupling to describe the underlying physical principles of AMO. On the basis of the impact of cumulative atmospheric forcing on ocean circulation, they also develop new AMOC indicators and shed light on the AMO's dynamics. To explain the remote impacts of AMO, the authors propose and identify the Atlantic-West Pacific trans-basin SST mode as a significant mode of global inter-oceanic interdecadal variability based on observational and model evidence. They discover that this mode started to change from a negative to a positive phase in the 1990s, which led to significant changes in the regional SST system in the Indian Ocean and the Arabian Sea. As a result, the warming rate of the Arabian Sea began to significantly accelerate in the 1990s. The Atlantic-West Pacific trans-basin SST mode corresponds to the synchronous changes of the Atlantic warm pool and the West Pacific warm pool, which have an important impact on the zonal Walker circulation; on the other hand, the Atlantic-West Pacific trans-basin SST mode can modulate the SST gradient in the northern and southern hemispheres, causing the variability of the meridional Hadley circulation and the north-south shift of the ITCZ position. These AMO-related changes have an impact on the climate in Asia as well as extreme weather (such tropical cyclones and heatwaves).
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 9
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    On the influences of the continental shelf bathymetry correction in Prydz Bay, East Antarctica (2023)
    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Details
    Publication Date: 2023-06-05
    Description: The bathymetry around Antarctica can govern the shelf sea circulations and play a key role in conditioning water masses. In Prydz Bay, the Prydz Bay Gyre and coastal currents are also determined by the continental shelf topography. However, due to the paucity of beam echo sounding data, the bathymetric datasets in Prydz Bay still have large uncertainties. With the aid of in situ hydrographic observations, this study focuses on the correction of an up-to-date bathymetric dataset and the resultant influences on the shelf circulation and the basal melting of the ice shelves. The corrected bathymetry mainly improves the biased shallow representations in the uncorrected bathymetric data set, with a maximum change of ~500 m deepening in the eastern flank of Prydz Bay. Sensitivity numerical experiments show that the bathymetric corrections in Prydz Bay have a significant impact on the circulation pattern and onshore warm water intrusions. In addition, the corrected bathymetry markedly decreases the heat transport towards the calving front of the Amery Ice Shelf. The onshore heat transport reduces by ~22.18% from ~5.23×10〈sup〉13〈/sup〉 J s〈sup〉-1〈/sup〉 to ~4.07×10〈sup〉13〈/sup〉 J s〈sup〉-1〈/sup〉 over the outer shelf. Over the inner shelf, the heat transport towards the Amery Ice Shelf reduces by ~18.15% from ~5.95×10〈sup〉13〈/sup〉 J s〈sup〉-1 〈/sup〉to ~4.87×10〈sup〉13〈/sup〉 J s〈sup〉-1〈/sup〉. Consequently, the temporally and spatially averaged basal melting rate of the Amery Ice Shelf reduces by ~13.04% from ~0.69 m yr〈sup〉-1〈/sup〉 to ~0.60 m yr〈sup〉-1〈/sup〉.
    Language: English
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  • 10
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    Multidecadal variability and decadal prediction of wintertime surface air temperature over the East Asian winter monsoon domain (2023)
    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Details
    Publication Date: 2023-05-22
    Description: This study investigates the influence of the winter NAO on the multidecadal variability of winter East Asian surface air temperature (EASAT) and its decadal prediction. The observational analysis shows that the winter EASAT and East Asian minimum SAT (EAmSAT) display strong in-phase fluctuations and a significant 60–80-year multidecadal variability, apart from a long-term warming trend. The winter EASAT experienced a decreasing trend in the last two decades, which is conducive to the occurrence of winter extremely cold events in East Asia in recent years. The winter NAO leads the detrended winter EASAT by 12–18 years with a maximumly significant positive correlation at the leading time of 15 years. Further analysis shows that ENSO may affect winter EASAT interannual variability, but does not affect the robust leading relationship between the winter NAO and EASAT. We present the coupled oceanic-atmospheric bridge (COAB) mechanism of the NAO influences on winter EASAT multidecadal variability through its accumulated delayed effect of ~15 years on the Atlantic Multidecadal Oscillation (AMO) and Africa–Asia multidecadal teleconnection (AAMT) pattern. Based on the COAB mechanism an NAO-based linear model for predicting winter decadal EASAT is constructed, with good hindcast performance. The winter EASAT for 2020–2034 is predicted to keep on fluctuating downward until ~2025, implying a high probability of occurrence of extremely cold events in coming winters in East Asia, and then turn towards sharp warming. The predicted 2020/21 winter EASAT is almost the same as the 2019/20 winter.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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