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  • 1995-1999  (18)
  • 1985-1989
  • 1995  (18)
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  • 1995-1999  (18)
  • 1985-1989
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  • 1
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 501-503 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Multiposition tangential Thomson scattering makes it possible to measure the profiles of the local drift velocity and current density of a tokamak plasma. To achieve a reasonably small observational error (20%) a high photon yield is required. In this paper we propose an optical system to increase the photon yield by about a factor of 7. Photons from a pulsed ruby laser are captured in a ring cavity by means of an electro-optical switch. The trapped laser beam recirculates about 14 times through the sampling volume which is part of the cavity, increasing the laser energy of 25 J to an effective energy of about 140 J. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A novel method is presented to analyze internal disruptions (sawteeth), observed with the five-camera soft-x-ray diagnostic at the Rijnhuizen Tokamak Project (RTP). Using four or five cameras, tomographic images with seven poloidal harmonics have been obtained throughout sawtooth crashes and precursor oscillations. The detection of cross-field transport and magnetic reconnection from the reconstructed tomographic images is complicated by the fact that (except during the final phase of the collapse) the time dependence is dominated by the m=1 ideal MHD displacement of the hot core in combination with plasma rotation. It is possible to define quantities, e.g., the plasma volume where the emissivity is within a certain range, whose change is only determined by cross-field transport or reconnection, and are not affected by displacement and rotation. The good spatial resolution of the 80-channel system enables us to compute these quantities with such an accuracy that their sensitivity to plasma rotation and MHD convection is small. Using this approach we find in the sawteeth studied so far that m=1 magnetic reconnection may take place, but affects less than half of the magnetic flux within the q=1 surface, thus ruling out complete reconnection as a mechanism for the final collapse of the hot core in these cases. © 1995 American Institute of Physics.
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  • 4
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An 80-channel visible-light tomography diagnostic is operational on the Rijnhuizen Tokamak Project. This diagnostic uses optical imaging systems from five directions in one poloidal plane to view emission by the plasma. For the application of tomography algorithms, measurements need to be preprocessed to take into account the properties of the imaging system. These properties have been measured and a consistent treatment is demonstrated. An example of a tomographic inversion of a glow-discharge plasma is given. Optical filters can be used to select various wavelength ranges. Because the imaging system gives large angles of incidence on the filter (〈16°), a study has been made to determine the minimum useful bandwidth of interference filters to select spectral lines, which was found to be 5 nm. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The Rutherford scattering diagnostic at TEXTOR has been used to investigate the time evolution of the ion velocity distribution during sawtooth activity. Coherent averaging techniques have been employed to obtain better statistics. The time evolutions of central ion and electron density were found to be strongly correlated in four out of five cases. In one case, where saturation of the sawteeth occurred, a discrepancy between the two has been found, which could be attributed to an influx of impurities towards the end of the sawtooth. Changes of about 20% in the central toroidal rotation of the bulk ions have been found during sawtooth crashes of neutral beam injected discharges, whereas no changes were found in the ohmic case. No statistically reliable statements can be made about changes in the ion temperature. © 1995 American Institute of Physics.
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  • 6
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The 20-channel heterodyne radiometer of the Rijnhuizen Tokamak Project (RTP) measures microwaves in the range between 86 and 146 GHz. The spatial resolution is ∼7–16 mm parallel and 25–1300 mm2 perpendicular to the viewing direction, depending on the position in the torus. A waveguide network gives the opportunity to do alternate measurements of X- and O-mode electron cyclotron emission (ECE) from the low-field side (LFS) and X-mode ECE from the high-field side (HFS). A backward wave oscillator is installed at the HFS, for the purpose of measuring the electron cyclotron absorption (ECA) of the plasma. This set-up also provides a possibility for fast relative calibration of the radiometer. To reduce the effects of multiple-pass reflections and standing waves, Macor viewing dumps are mounted at both sides. A comparison of HFS and LFS ECE measurements during electron cyclotron heating will be given as a first result. First results of ECA measurements were obtained but will be presented in the future. © 1995 American Institute of Physics.
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  • 7
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A four-channel pulsed radar reflectometry system has been developed for the Rijnhuizen Tokamak Project. The system combines a high spatial and temporal resolution with limited access demands to the tokamak plasma. Steady-state density profiles as measured with the pulsed radar system match very well to the profiles as measured by Thomson scattering and by interferometry. As will be illustrated in this paper, the diagnostic is able to follow fast phenomena as pellet injection and plasma disruptions as well as MHD oscillations. © 1995 American Institute of Physics.
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 3407-3423 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Interferometry is a standard technique for measuring the line-integrated electron density of magnetically confined plasmas. It is based on the fact that an electromagnetic wave, on its passage through a plasma, experiences a phase change with respect to the vacuum situation. Moreover, the plane of polarization of the wave will in general rotate because the plasma is birefringent. The total (Faraday) rotation angle of the wave, which can be measured by polarimetric techniques, is proportional to the line-integrated value of the magnetic field component parallel to the beam. The optimum wavelength for interferometry/polarimetry, for diagnosing magnetically confined plasmas is in the far-infrared and infrared spectral region. To invert the line-integrated data of the electron density and magnetic field component to local values, without using too stringent assumptions on the plasma symmetry, it is necessary to probe the plasma along multiple chords. In many confinement devices this is done by using a limited number of discrete probing chords. In recent years much attention has been devoted to the development of multichannel interferometer/polarimeter systems with a much better coverage of the plasma, which could be achieved by expanding the probing beam either to a slab- or a fanlike beam, covering almost the complete minor cross section of the plasma. A much higher number of detectors can be implemented in this way, thus substantially improving the spatial resolution of the measurements. In this paper the present status of interferometer/polarimeter systems featuring slablike or fanlike probing beams will be reviewed. Results of detailed measurements that have been performed to study the effect of magnetohydrodynamic activity (in particular sawteeth), disruptions, additional heating, and pellet injection on the electron density distribution, will be used to illustrate the merits of interferometry/polarimetry with high spatial resolution. © 1995 American Institute of Physics.
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  • 9
    ISSN: 1573-4951
    Keywords: Histamine ; H1-receptor ; H1-agonists ; H1-antagonists ; G-protein coupled receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A modelling study has been carried out, investigating the binding of histamine (Hist), 2-methylhistamine (2-MeHist) and 2-phenylhistamine (2-PhHist) at two postulated agonistic binding sites on transmembrane domain 5 (TM5) of the histamine H1-receptor. For this purpose a conformational analysis study was performed on three particular residues of TM5, i.e., Lys200, Thr203 and Asn207, for which a functional role in binding has been proposed. The most favourable results were obtained for the interaction between Hist and the Lys200/Asn207 pair. Therefore, Lys200 was subsequently mutated and converted to an alanine, resulting in a 50-fold decrease of H1-receptor stimulation by histamine. Altogether, the data suggest that the Lys200/Asn207 pair is important for activation of the H1-receptor by histamine. In contrast, analogues of 2-PhHist seem to belong to a distinct subclass of histamine agonists and an alternative mode of binding is proposed in which the 2-phenyl ring binds to the same receptor location as one of the aromatic rings of classical histamine H1-antagonists. Subsequently, the binding modes of the agonists Hist, 2-MeHist and 2-PhHist and the H1-antagonist cyproheptadine were evaluated in three different seven-α-helical models of the H1-receptor built in homology with bacteriorhodopsin, but using three different alignments. Our findings suggest that the position of the carboxylate group of Asp116 (TM3) within the receptor pocket depends on whether an agonist or an antagonist binds to the protein; a conformational change of this aspartate residue upon agonist binding is expected to play an essential role in receptor stimulation.
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  • 10
    Publication Date: 1995-06-01
    Print ISSN: 0034-6748
    Electronic ISSN: 1089-7623
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
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