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  • 2015-2019  (144)
  • 1995-1999  (62)
  • 1980-1984  (18)
  • 2018  (144)
  • 1998  (31)
  • 1995  (31)
  • 1983  (18)
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  • 2015-2019  (144)
  • 1995-1999  (62)
  • 1980-1984  (18)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Syntheses of [6,7-15N]-Adenosine, [6,7-15N]-2'-Deoxyadenosine, and [7-15N]-Hypoxanthine (1995)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 117 (1995), S. 11669-11672 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00152a006
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  • 2
    Electronic Resource
    Electronic Resource
    A TECHNIQUE TO RECONSTRUCT RIVER DISCHARGE HISTORY FROM TREE-RINGS (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 19 (1983), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: : Cores were obtained from several tree species located both on a river floodplain and a nearby terrace. A ratio of annual tree growth on floodplains to terrace growth was developed and shown to be related to the annual river discharge. Growth ratios from the time prior to written records can therefore be used to reconstruct river discharge and infer past unrecorded flood frequency. Oak and basswood ratios yielded the best models for discharge reconstruction, whereas those of elm and birch were less useful. This method permits reconstruction of river discharge from an assemblage of growth cores obtained within a relatively small area.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.1983.tb05311.x
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  • 3
    Electronic Resource
    Electronic Resource
    Atom bouncers have it taped (1995)
    [s.l.] : Nature Publishing Group
    Nature 377 (1995), S. 291-292 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] EXPERIMENTERS now have a new set of tricks for manipulating and storing cold atoms — and the key ingredients are familiar high-street commodities. Edward Hinds and co-workers at Yale University have repeatedly bounced rubidium atoms from magnetic tape of the kind used to record audio ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/377291a0
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  • 4
    Electronic Resource
    Electronic Resource
    Genetic kin recognition: honey bees discriminate between full and half sisters (1983)
    [s.l.] : Nature Publishing Group
    Nature 302 (1983), S. 147-148 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Queen honey bees mate with a number of different drones before they lay their first eggs11. The sperm, to some extent, mix in the spermatheca and the hive contains several distinct patrilineal worker groups of full sisters while the workers are matrilineal half sisters across groups12'13. In ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/302147a0
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  • 5
    Electronic Resource
    Electronic Resource
    Population dynamics and harvesting of semelparous species with phenotypic and genotypic variability in reproductive age (1995)
    Springer
    Journal of mathematical biology 33 (1995), S. 521-556 
    Details
    ISSN: 1432-1416
    Keywords: Population dynamics modeling ; Evolutionarily stable strategies ; Polymorphic life histories ; Age-at-maturity ; Harvesting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract We study the evolution of polymorphic life histories in anadromous semelparous salmon and the effects of harvesting. We derive dynamic phenotypic and genetic ESS models for describing the evolutionary dynamics. We show in our deterministic analysis that polymorphisms are not possible in a panmictic random mating population. Instead, genetic or behavioral polymorphisms may be observed in populations with assortative mating systems. Positive assortative mating may be supported and generated by behavioral and phenotypic traits like male mate choice, spawning ground selection by phenotype, or within-river homing-migration-distance by size. In the case of an evolutionarily stable dimorphism, the ESS is characterized by a reproductive ideal free distribution such that at an equilibrium the individuals are indifferent from the fitness point of view between the two life histories of early and late reproduction. Different strategy models - that is, phenotypic and genetic ESS models - yield identical behavioral predictions and, consequently, genetics does not seem to play an important role in the present model. An evolutionary response to increased fishing mortality is obvious and may have resource management implications. High sea fishing mortalities drive the populations toward early spawning. Thus it is possible that unselective harvesting at sea may eliminate, depending on the biological system, behavioral polymorphisms or genetic heterozygozity and drive the population to a monomorphic one. If within-river homing migration distances depend on the size of fish, unselective harvesting at sea, or selective harvesting of spawning runs in rivers, may reduce local population sizes on spawning grounds high up rivers. Finally, harvesting in a population may cause a switch in a dominant life-history strategy in a population so that anticipated sustainable yields cannot be realized in practice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00163041
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  • 6
    Electronic Resource
    Electronic Resource
    Transgenic analysis of the 5′- and 3′-flanking regions of the NADH-dependent hydroxypyruvate reductase gene from Cucumis sativus L. (1995)
    Springer
    Plant molecular biology 28 (1995), S. 821-836 
    Details
    ISSN: 1573-5028
    Keywords: cucumber ; light-regulated gene expression ; NADH-dependent hydroxypyruvate reductase ; organ-specific gene expression ; peroxisome ; photorespiration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The 5′- and 3′-flanking regions of HPRA, a cucumber gene that encodes hydroxypyruvate reductase, were evaluated for regulatory activity with respect to light responsiveness and organ specificity. To define the functional regions of the 5′-flanking region of HPRA, a series of deletions was generated and the remaining portions fused to the β-glucuronidase (GUS) reporter gene (uidA) containing a minimal 35S promoter truncated at −90. The region from −66 to +39 was found to be necessary for light-regulated expression of the uidA reporter gene, while the region from −382 to −67 was found to be necessary for its leaf-specific expression. Further deletion of the HPRA 5′ flanking region to −590 resulted in high levels of root expression, suggesting the presence of a negative regulatory element responsible for silencing root expression of the HPRA gene between −590 and −383. The 3′-flanking region of the HPRA gene downstream of the polyadenylation site contains several sequence motifs resembling regulatory elements present in the promoters of several light-responsive genes. An 823 bp portion of the HPRA 3′-flanking region containing these putative regulatory elements enhanced GUS expression in leaves when placed downstream of the uidA reporter gene in the forward orientation, but not in the reverse orientation. When placed 5′ of the −90 35S promoter, the 823 bp fragment enhanced slightly, independently of orientation, the root tip-specific expression pattern intrinsic to the −90 35S promoter, indicating that in some cases this region can act as a transcriptional enhancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00042068
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  • 7
    Electronic Resource
    Electronic Resource
    Interaction of DNA-binding proteins with the 5′-flanking region of a cytokinin-responsive cucumber hydroxypyruvate reductase gene (1998)
    Springer
    Plant molecular biology 38 (1998), S. 713-723 
    Details
    ISSN: 1573-5028
    Keywords: cucumber ; cytokinin-responsive ; DNA-binding proteins ; hydroxypyruvate reductase ; transcription
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Transcription of the cucumber hpr-A gene is responsive to cytokinin and light. To investigate the molecular basis for transcriptional regulation by cytokinin, we have identified DNA sequences and proteins that may be involved in the regulation of hpr-A gene expression. Transient expression assays in etiolated cucumber cotyledons indicate that the 315 bp fragment (−382 to −67) contains sequences necessary for cytokinin responsiveness of the luciferase reporter gene. Band shift assays detected cytokinin-enhanced and -reduced protein binding sites in a 97 bp fragment (−382 to −285) upstream of the hpr-A gene. DNase I footprinting identified two protein-protected sites, a 15 bp sequence, 5′-AAATGACGAAAATGC-3′, that contains an as-1 TGACG motif found in other plant promoters, and a 13 bp sequence, 5′-AAGATTGATTGAG-3′, of unknown function. Two-dimensional band shift analysis of the cytokinin-responsive DNA protein complex revealed the presence of six DNA protein interactions. Band shift assays showed that cytokinin and light have different effects on the interaction of nuclear proteins to the 97 bp fragment of the hpr-A gene. These data suggest that cytokinin and light do not share identical signal transduction pathways in regulating hpr-A gene expression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006034932322
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  • 8
    Electronic Resource
    Electronic Resource
    Avoiding metric monsters: A design metrics approach (1995)
    Springer
    Annals of software engineering 1 (1995), S. 43-55 
    Details
    ISSN: 1573-7489
    Keywords: Design metrics ; design metrics analyzer ; metrics model ; software metrics ; software quality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Metric monsters are stumbling blocks that prevent software metrics-guided methodologies from attaining product and process improvement. Metric monsters can occur during the identification, collection or application of software metrics. In our research, we have developed and tested our design metrics over a five-year period and have found them to be excellent predictors of error-prone modules. Based on this research, we will identify some of the monsters that occur in the quantitative analyses of software and its development processes, and present our approach in formulating a design metrics model that avoids these monsters. This model consists of software tools, guidelines and actions for the application of software design metrics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02249045
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  • 9
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    Gene cluster conservation provides insight into cercosporin biosynthesis and extends production to the genus Colletotrichum (2018)
    National Academy of Sciences
    Details
    Publication Date: 2018-05-29
    Description: Species in the genus Cercospora cause economically devastating diseases in sugar beet, maize, rice, soy bean, and other major food crops. Here, we sequenced the genome of the sugar beet pathogen Cercospora beticola and found it encodes 63 putative secondary metabolite gene clusters, including the cercosporin toxin biosynthesis (CTB) cluster. We show that the CTB gene cluster has experienced multiple duplications and horizontal transfers across a spectrum of plant pathogenic fungi, including the wide-host range Colletotrichum genus as well as the rice pathogen Magnaporthe oryzae. Although cercosporin biosynthesis has been thought to rely on an eight-gene CTB cluster, our phylogenomic analysis revealed gene collinearity adjacent to the established cluster in all CTB cluster-harboring species. We demonstrate that the CTB cluster is larger than previously recognized and includes cercosporin facilitator protein, previously shown to be involved with cercosporin autoresistance, and four additional genes required for cercosporin biosynthesis, including the final pathway enzymes that install the unusual cercosporin methylenedioxy bridge. Lastly, we demonstrate production of cercosporin by Colletotrichum fioriniae, the first known cercosporin producer within this agriculturally important genus. Thus, our results provide insight into the intricate evolution and biology of a toxin critical to agriculture and broaden the production of cercosporin to another fungal genus containing many plant pathogens of important crops worldwide.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 10
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    Pseudorapidity and transverse momentum dependence of flow harmonics in pPb and PbPb collisions (2018)
    American Physical Society
    Details
    Publication Date: 2018-10-05
    Print ISSN: 2469-9985
    Electronic ISSN: 2469-9993
    Topics: Physics
    Published by American Physical Society
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