ISSN:
0377-0486
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
Myelin membrane and its proteolipid protein (PLP) have been examined by infrared and Raman spectroscopy to provide information about the secondary structure of proteins and conformation of lipid chains. Splitting of the amide I modes in the vibrational spectra and locations of amide A, I, II, III and V bands indicate that the polypeptide arrangement in both membrane systems is mainly helical. The β-form is also present, its amount being higher in PLP. Raman spectra in the C—C and C—H stretching regions show significant differences concerning intra- and inter-chain lipid order, which is greater in PLP.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jrs.1250180704
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