ISSN:
1573-904X
Keywords:
retinoids
;
antihyperkeratinization
;
antihyperproliferation
;
antihyperactive sebaceous gland
;
hypervitaminosis A
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Evaluation of 13-cis-12-substituted analogues of retinoic acid in a series of dermatologic screens has revealed that structural modifications can lead to selectivity and specificity. An analogue, 11-cis,13-cis-12-hydroxymethylretinoic acid, δ-lactone, has been found to have good activity and to be devoid of topical and systemic toxicity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1018938920796
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