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  • 1
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    Micro- and Nanofluidics for Bionanoparticle Analysis (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-11
    Description: Bionanoparticles such as microorganisms and exosomes are recoganized as important targets for clinical applications, food safety, and environmental monitoring. Other nanoscale biological particles, includeing liposomes, micelles, and functionalized polymeric particles are widely used in nanomedicines. The recent deveopment of microfluidic and nanofluidic technologies has enabled the separation and anslysis of these species in a lab-on-a-chip platform, while there are still many challenges to address before these analytical tools can be adopted in practice. For example, the complex matrices within which these species reside in create a high background for their detection. Their small dimension and often low concentration demand creative strategies to amplify the sensing signal and enhance the detection speed. This Special Issue aims to recruit recent discoveries and developments of micro- and nanofluidic strategies for the processing and analysis of biological nanoparticles. The collection of papers will hopefully bring out more innovative ideas and fundamental insights to overcome the hurdles faced in the separation and detection of bionanoparticles.
    Keywords: TA1-2040 ; T1-995 ; n/a ; magnetic field ; microfluidic device ; ballpoint pen printing ; paper-based microfluidic device ; online analysis ; nanoporous membrane ; dielectric film ; digital microfluidic chip ; HIV diagnostics ; precipitation ; optically induced dielectrophoresis (ODEP) ; digital microfluidic device ; fluorescence ; ferrofluids ; cancer metastasis ; flow focusing ; image processing ; electrowetting ; light diffraction ; lensfree ; nanoparticle characterization ; multi-step assay ; cell isolation ; biomarker detection ; microparticles ; conductive electrode ; single particle analysis ; plastic wrap ; second-hand smoke ; flow control ; surface acoustic wave ; droplet actuation ; circulating tumour cells (CTCs) ; lipid nanoparticles ; crop disease ; cross-flow filtration ; oxidized hollow mesoporous carbon nanosphere ; microfluidic systems ; 3-ethenylpyridine ; microfluidic ; microfluidics ; COMSOL ; plug flow mixer ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
    Format: application/octet-stream
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  • 2
    Electronic Resource
    Electronic Resource
    The Growth of Carbon Nanostructure on the Mechanical-Milling-Derived Catalyst Precursors (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Journal of metastable and nanocrystalline materials Vol. 23 (Jan. 2005), p. 383-386 
    Details
    ISSN: 1422-6375
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Mechanical milling was employed to prepare the nanocomposite precursors for the catalytic growth of carbon nanostructures. For alumina substrates, our study showed that mechanical-millingderived catalyst precursors possessed high hydrogen reduction efficiency that in turn enabled the high yield of CNTs. The alloying effects presented by the mechanical milling could accelerate thesubstitutional reactions between the parent oxides and thus the quality of CNTs was apparently improved. In addition, by using water-soluble substrates such as NaCl, we realized large-scale formation of carbon-encapsulated metal nanoparticles (CEMNs) that can be completely separated by a simple washing process. It was found that the morphologies of as-obtained carbon nanostructures were strongly dependent on the substrate effects. By selecting different salt substrates, we can strategically change the morphologies of the as-obtained nanostructures, from CNTs to CEMNs and the intermediate state between CNTs and CEMNs, such as quasi-nanocages
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/43/transtech_doi~10.4028%252Fwww.scientific.net%252FJMNM.23.383.pdf
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  • 3
    Electronic Resource
    Electronic Resource
    SAXS Characterization of Nanochannels in Polymer-Derived SiC Fibers (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 336-338 (Apr. 2007), p. 1301-1303 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In the preparation of polymer-derived SiC fibers, nanochannels are believed to be formed in theearly pyrolysis stages due to loss of large volumes of pyrolysis gases. In this paper, small angle X-rayscattering (SAXS) was applied to the characterization and calculation of nanochannels in partiallypyrolyzedSiC fibers. The SAXS measurements showed that nanochannels with a radius of 1.0-20 nmwere formed for fibers heat-treated at 973K and 1173K. But their distributions were not continuous and atlower part of the distribution, a peak value was observed at about 1.2nm. This means if the nanochannelsare finely controlled, the partially-pyrolyzed SiC fibers have great potential application in the fields ofhydrogen storage, gas separation, and so on
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.336-338.1301.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Mechanochemical Synthesis of Fe-Based Nanocomposites and Their Application in the Catalytic Formation of Carbon Nanostructures (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 111 (Apr. 2006), p. 183-186 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Mechanochemical process was employed to prepare Fe/MgO and Fe/NaClnanocomposites. The carbon nanostructures (nanotubes and carbon-encapsulated Fe nanoparticles) were successfully synthesized using two nanocomposites as the catalyst. Our wok revealed that themorphology of Fe nanoparticles in the Fe/MgO nanocomposites depended on the distribution and particle size of iron oxides in the precursors. The size of Fe nanoparticles greatly affected their catalytic properties and the morphologies of carbon nanotubes. The successful carbon encapsulation of Fe nanoparticles was achieved by using the mechanochemically derived Fe/NaCl catalyst
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/22/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.111.183.pdf
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  • 5
    Electronic Resource
    Electronic Resource
    A Partially Observed Model for Micromovement of Asset Prices with Bayes Estimation via Filtering (2003)
    350 Main Street , Malden , MA 02148 , USA , and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Publishers, Inc.
    Mathematical finance 13 (2003), S. 0 
    Details
    ISSN: 1467-9965
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mathematics , Economics
    Notes: A general micromovement model that describes transactional price behavior is proposed. The model ties the sample characteristics of micromovement and macromovement in a consistent manner. An important feature of the model is that it can be transformed to a filtering problem with counting process observations. Consequently, the complete information of price and trading time is captured and then utilized in Bayes estimation via filtering for the parameters. The filtering equations are derived. A theorem on the convergence of conditional expectation of the model is proved. A consistent recursive algorithm is constructed via the Markov chain approximation method to compute the approximate posterior and then the Bayes estimates. A simplified model and its recursive algorithm are presented in detail. Simulations show that the computed Bayes estimates converge to their true values. The algorithm is applied to one month of intraday transaction prices for Microsoft and the Bayes estimates are obtained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1467-9965.t01-1-00022
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  • 6
    Electronic Resource
    Electronic Resource
    Neuroanatomy of Aging Brain (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 717 (1994), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1994.tb12071.x
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of Spinning Techniques on the Mechanical Properties of Polymer-Derived Silicon Carbide Fiber (2002)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 224-226 (June 2002), p. 651-656 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/46/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.224-226.651.pdf
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  • 8
    Electronic Resource
    Electronic Resource
    A New Type Gene Delivery System – Gene Nanoparticles (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 288-289 (June 2005), p. 143-146 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A reporter gene pEGFP and a therapeutic antisense monocyte hemotactic protein-1(MCP-1) gene were encapsulated into poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) using an emulsification / solvent evaporation technique. The gene-NPs were around 300 nm in diameter with very narrow size distribution. The encapsulation efficiency of DNA was significantly improved when poly (lysine) was used in cooperation with DNA. The NPs demonstrated a steady in vitro release of DNA with more that 95% of total enclosed DNA released within 14 days. In cellculture, pEGFP -loaded NPs were able to express in smooth muscle cells at a level same as that of Lipofectin induced plasmid. To observe the effects of antisense MCP-1 NPs on the inhibition of restenosis, balloon catheter-induced injury was used to establish an intimal hyperplasia model of rabbit carotid artery. Antisense MCP-1 expression was confirmed in the artery tissue with local delivery of the therapeutic NP into the injured artery. Intima/media ratio of arteries treated with the antisense NPs was reduced by 43% compared with control group. In conclusion, NP could be an effective gene carrier for intravascular site-specific gene therapy
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/49/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.288-289.143.pdf
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  • 9
    Electronic Resource
    Electronic Resource
    Work Hardening and Flow Softening of γ-TiAl Containing Ni (2004)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 449-452 (Mar. 2004), p. 833-836 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper presents the true stress - strain curves and data analyses of aNi-containing TiAl and its reference alloy based on the isothermal compression tests at 1000°C and 0.01 - 1.0s〈sup〉-1〈/sup〉 strain rates. The results show that the minor Ni addition makes the flow softening coming sooner and therefore significantly lowers the peak stress. Those effects, in addition with a better balance between the work hardening and flow softening during hot deformation, improve the steady state flow behavior of TiAl. The Ni-influence mechanisms are also suggested based on the TEM observation of dislocation configurations and lamellar breakdown during the deformation
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/08/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.449-452.833.pdf
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  • 10
    Electronic Resource
    Electronic Resource
    Photoreceptor cell rescue in retinal degeneration ( rd ) mice by in vivo gene therapy (1996)
    [s.l.] : Nature Publishing Group
    Nature medicine 2 (1996), S. 649-654 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Mutations in the β subunit of the cGMP phosphodiesterase gene (βPDE) can cause a recessively inherited retinal degeneration in several species, including mice, dogs and humans. We tested the possibility of altering the course of retinal degeneration in the rd mouse through subretinal ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nm0696-649
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