ISSN:
1600-5759
Source:
Crystallography Journals Online : IUCR Backfile Archive 1948-2001
Topics:
Chemistry and Pharmacology
,
Geosciences
,
Physics
Notes:
The title compound, C17H16N2O3, is an antagonist for AMPA/kainate receptors. The molecule has its seven-membered oxadiazole ring in a boat conformation. Asymmetry of the two methoxy bond angles is evident, with (Me)O—C—C angles of 115.45 (12) and 124.78 (13)°, and 114.67 (12) and 125.31 (12)°. A centrosymmetric dimer involving the HN—CO moieties, with an N...O distance of 2.876 (2) Å, graph set R{_2^2}(8), is further linked into chains through methoxy Csp3—H...N hydrogen bonds, with a C...N distance of 3.418 (2) Å.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1107/S0108270101011805
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