Publication Date:
2016-05-26
Description:
Article The spectraplakin protein ACF7 binds to actin at focal adhesions and targets microtubule plus ends to focal adhesions, promoting their disassembly. Here the authors reveal that ACF7 is phosphorylated by Src/FAK, and this regulates actin binding and focal adhesion dynamics in vitro and in vivo . Nature Communications doi: 10.1038/ncomms11692 Authors: Jiping Yue, Yao Zhang, Wenguang G. Liang, Xuewen Gou, Philbert Lee, Han Liu, Wanqing Lyu, Wei-Jen Tang, Shao-Yu Chen, Feng Yang, Hong Liang, Xiaoyang Wu
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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