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  • 1
    Publication Date: 2012-12-28
    Description: Background: Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (ob) and the leptin receptor (ob-R) in the pressure-overloaded rat heart. We also examined gene expressions in culture cardiac myocytes to clarify which hypertension-related stimulus induces these genes. Results: Pressure overload was produced by ligation of the rat abdominal aorta, and ob and ob-R isoform mRNAs were measured using a real-time polymerase chain reaction (PCR). We also measured these gene expressions in neonatal rat cardiac myocytes treated with angiotensin II (ANGII), endothelin-1 (ET-1), or cyclic mechanical stretch. Leptin and the long form of the leptin receptor (ob-Rb) gene were significantly increased 4 weeks after banding, but expression of the short form of the leptin receptor (ob-Ra) was unchanged. ob-Rb protein expression was also detected by immunohistochemistry in hypertrophied cardiac myocytes after banding. Meanwhile, plasma leptin concentrations were not different between the control and banding groups. In cultured myocytes, ANGII and ET-1 increased only ob mRNA expression. However, mechanical stretch activated both ob and ob-Rb mRNA expression in a time-dependent manner, but ob-Ra mRNA was unchanged by any stress. Conclusions: We first demonstrated that both pressure mediated hypertrophy and mechanical stretch up-regulate ob-Rb gene expression in heart and cardiac myocytes, which are thought to be important for leptin action in cardiac myocytes. These results suggest a new local mechanism by which leptin affects cardiac remodeling in pressure-overloaded hearts.
    Electronic ISSN: 1471-2121
    Topics: Biology , Medicine
    Published by BioMed Central
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  • 2
    Publication Date: 2017-09-11
    Description: A quasi-stationary front, called the baiu front, often appears during the early-summer rainy season in East Asia (baiu in Japan). The present study examines how precipitation characteristics during the baiu season are determined by the large-scale environment, using satellite observation three-dimensional precipitation data. Emphasis is placed on the effect of subtropical jet (STJ) and lower-tropospheric convective instability (LCI). A rainband appears together with a deep moisture convergence to the south of the STJ. Two types of mesoscale rainfall events (REs; contiguous rainfall areas), which are grouped by the stratiform precipitation ratio (SPR; stratiform precipitation over total precipitation), are identified: moderately stratiform REs (SPR of 0%–80%) representing tropical organized precipitation systems and highly stratiform REs (SPR of 80%–100%) representing midlatitude precipitation systems associated with extratropical cyclones. As the STJ becomes strong, rainfall from both types of mesoscale precipitation systems increases, with a distinct eastward extension of a midtropospheric moist region. In contrast, small systems appear regardless of the STJ, with high dependency on the LCI. The results indicate that the STJ plays a role in moistening the midtroposphere owing to ascent associated with secondary circulation to the south of the STJ, producing environments favorable for organized precipitation systems in the southern part of the rainband. The horizontal moisture flux convergence may also contribute to precipitation just along the STJ. On the other hand, the LCI plays a role in generating shallow convection. In high-LCI conditions, deep convection can occur without the aid of mesoscale organization.
    Print ISSN: 0894-8755
    Electronic ISSN: 1520-0442
    Topics: Geography , Geosciences , Physics
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  • 3
    Publication Date: 2009-10-15
    Description: The spectral latent heating (SLH) algorithm was developed to estimate latent heating profiles for the Tropical Rainfall Measuring Mission Precipitation Radar (TRMM PR). The method uses TRMM PR information (precipitation-top height, precipitation rates at the surface and melting level, and rain type) to select heating profiles from lookup tables (LUTs). LUTs for the three rain types—convective, shallow stratiform, and anvil rain (deep stratiform with a melting level)—were derived from numerical simulations of tropical cloud systems from the Tropical Ocean and Global Atmosphere Coupled Ocean–Atmosphere Response Experiment (TOGA COARE) using a cloud-resolving model (CRM). The two-dimensional (2D) CRM was used in previous studies. The availability of exponentially increasing computer capabilities has resulted in three-dimensional (3D) CRM simulations for multiday periods becoming increasingly prevalent. In this study, LUTs from the 2D and 3D simulations are compared. Using the LUTs from 3D simulations results in less agreement between the SLH-retrieved heating and sounding-based heating for the South China Sea Monsoon Experiment (SCSMEX). The level of SLH-estimated maximum heating is lower than that of the sounding-derived maximum heating. This is explained by the fact that using the 3D LUTs results in stronger convective heating and weaker stratiform heating above the melting level than is the case if using the 2D LUTs. More condensate is generated in and carried from the convective region in the 3D model than in the 2D model, and less condensate is produced by the stratiform region’s own upward motion.
    Print ISSN: 0894-8755
    Electronic ISSN: 1520-0442
    Topics: Geography , Geosciences , Physics
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  • 4
    Publication Date: 2014-07-10
    Description: Over the eastern Pacific, recent studies have shown that a shallow large-scale meridional circulation with its return flow just above the boundary layer coexists with a deep Hadley circulation. This study examines how the vertical structure of large-scale circulations is related to satellite-observed individual precipitation properties over the eastern Pacific in boreal autumn. Three reanalysis datasets are used to describe differences in their behavior. The results are compared among reanalyses and three distinctly different convection periods, which are defined according to their radar echo depths. Shallow and deep circulations are shown to often coexist for each of the three periods, resulting in the multicell circulation structure. Deep (shallow) circulations preferentially appear in the mostly deep (shallow) convection period of radar echo depths. Thus, depth of convection basically corresponds to which circulation branch is dominant. This anticipated relationship between the circulation structure and depths of convection is common in all three reanalyses. Notable differences among reanalyses are found in the mid- to upper troposphere in either the time-mean state or the composite analysis based on the convection periods. Reanalyses have large variations in characteristics associated with deep circulations such as the upper-tropospheric divergence and outflows and the midlevel inflows, which are consistent with their different profiles of latent heating in the mid- to upper troposphere. On the other hand, discrepancies in shallow circulations and shallow convection are also found, but they are not as large as those in deep ones.
    Print ISSN: 0894-8755
    Electronic ISSN: 1520-0442
    Topics: Geography , Geosciences , Physics
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  • 5
    Publication Date: 2014-08-07
    Description: Using 10-yr high-resolution satellite and reanalysis data, the synoptic-scale dual structure of precipitable water (PW), in which the southern and northern bands straddled at the ITCZ produce zonally propagating meridional dipoles, is observed over the eastern Pacific (EP) during boreal summer and fall. Composites indicate that the PW dipole, concurrent with the dipole-like filtered divergence, has a shift to the west of the anomalously cyclonic circulation. The vertical structure of filtered meridional wind is characterized by a wavenumber-1 baroclinic mode, and the vertical motion has two peaks situated at 850 and 300 hPa, respectively. To the east of the PW dipole, the shallow convection is embedded within the deep convection, forming a multilevel structure of meridional wind on the ITCZ equatorward side. To the west of the PW dipole, the deep convection tends to be suppressed because of the invasion of midlevel dry air advected by northerly flows. The generation and propagation of the dual PW band can be attributed to the divergence and advection terms related to specific humidity and three-dimensional wind. By comparison, the PW anomalies over the western North Pacific, only exhibiting a single band, coincide with the centers of synoptic disturbances with a barotropic vertical structure. Because of the weakening of lower-level divergence, the vertical motion, and the horizontal gradient of PW, the synoptic-scale PW signal is reduced significantly. The typical cases and statistics confirm that the strong meridional dipoles and westward-propagating disturbances are closely associated with the distortion and breakdown of ITCZ over the EP.
    Print ISSN: 0894-8755
    Electronic ISSN: 1520-0442
    Topics: Geography , Geosciences , Physics
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  • 6
    Publication Date: 2014-07-29
    Description: Contrasts in precipitation characteristics across the baiu front are examined with Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (PR) data near Japan during June–July (1998–2011). The vertical structure of atmospheric stratification differs between the tropics and midlatitudes. On an average, the baiu front is found around the latitude that roughly divides the midlatitude atmosphere from the tropical atmosphere. Precipitation characteristics are compared between the southern and northern sides of the reference latitude of the baiu front, which is detected with equivalent potential temperature at 1000 hPa of 345 K in terms of the boundary between the tropics and midlatitudes. The results show that there are obvious differences in precipitation characteristics between the southern and northern sides. In the south, convective rainfall ratios (CRRs) are 40%–60%, which are larger than those in the north (20%–40%). Greater rainfall intensity and taller/deeper precipitation are also observed in the south. Moreover, the characteristics of precipitation features (PFs), which are contiguous areas of nonzero rainfall, differ between the southern and northern sides. In the north, wide stratiform precipitation systems with CRRs of 0%–40% and heights of 8–11 km are dominant. In the south, organized precipitation systems with heights of 12–14 km and CRRs of 30%–50% and those with very large heights (14–17 km) and CRRs of 50%–80% are dominant in addition to wide stratiform precipitation systems. These results suggest that the mechanisms to bring rainfall are different between the southern and northern regions of the baiu front.
    Print ISSN: 0894-8755
    Electronic ISSN: 1520-0442
    Topics: Geography , Geosciences , Physics
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  • 7
    Publication Date: 2012-09-01
    Description: Synoptic-scale westward-propagating disturbances over the eastern Pacific (EP) are analyzed in boreal autumn, utilizing spectral analysis, composite analysis, and energy budget analysis. The results are compared with those over the western Pacific (WP). Spectral peaks of total precipitable water (TPW) and vertical velocity at 850 hPa (ω850), and outgoing longwave radiation (OLR) are detected at periods of ~3–7 days over the EP. Meanwhile over the WP, a spectral peak of OLR is pronounced, but peaks of TPW and ω850 are not detected. Composite analysis reveals that disturbances that have a coupled structure, with a vortex at its center near ~9°N and a mixed Rossby–gravity (MRG) wave–type disturbance, frequently exist over the EP. At the same time, the disturbances have a double-deck structure associated with divergence both in the upper and in the middle to lower troposphere. These disturbances are associated with both deep convection and congestus, which generate kinetic energy of the disturbance in the upper and in the lower troposphere, respectively. Examining diabatic heating in relation to the coupled disturbances, deep heating with the peak at the height of ~7.5 km is greatest in the northeastern part of the vortex. The coupled MRG wave–type disturbance provides a relatively deep cross-equatorial southerly flow into the northeastern part of the vortex. It is suggested that deep rain is maintained with the existence of deep convergence produced by the coupled disturbances over the EP, where a very shallow convergence field exists on average.
    Print ISSN: 0027-0644
    Electronic ISSN: 1520-0493
    Topics: Geography , Geosciences , Physics
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  • 8
    Publication Date: 2012-08-18
    Print ISSN: 0148-0227
    Electronic ISSN: 2156-2202
    Topics: Geosciences
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  • 9
    Publication Date: 2008-10-01
    Print ISSN: 0027-0644
    Electronic ISSN: 1520-0493
    Topics: Geography , Geosciences , Physics
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  • 10
    Publication Date: 2012-09-01
    Description: Differences in the characteristics of rain systems in the eastern Pacific (EP) intertropical convergence zone (ITCZ) and the western Pacific (WP) warm pool are quantitatively examined in relation to the large-scale environment. This study mainly uses precipitation feature (PF) data observed by the precipitation radar (PR) on board the Tropical Rainfall Measuring Mission (TRMM). The PFs are classified into four types according to their areas and maximum heights. Rain from tall unorganized systems and very tall organized systems tends to be dominant in high-SST regions such as the WP. On the other hand, the EP has more rain from congestus and organized systems with moderate heights than the WP. It is shown that shallow rain from congestus and moderately deep rain from organized systems are highly correlated with shallow (1000–925 hPa) convergence fields with coefficients of 0.75 and 0.66, respectively. These relationships between characteristics of rain systems and the large-scale environment are robust through all seasons.
    Print ISSN: 0027-0644
    Electronic ISSN: 1520-0493
    Topics: Geography , Geosciences , Physics
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