ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Abstract. Fluoride (F-)-substituted type-B carbonate-containing hydroxyapatites (CHAPs) were prepared as bone substitutes with a F-releasing ability. The F- contents in the F-substituted CHAPs were 16-22 times larger than that in normal adult human bones. The carbonate contents in the F-substituted CHAPs corresponded to that in human bones. The F-substituted CHAPs released F- inan acetic acid – sodium acetate buffer at pH 4.9; within only 3 h, the F- concentration in the buffer increased to more than 63.9 µg L-1, which was 1.5~8.9 times higher than that in a body fluid of normal adult humans. Although the F- concentration rapidly decreased probably due to the precipitation of a certain phase containing F-, the F-substituted CHAPs exhibited the ability toincrease the F- concentration in a body fluid by bone resorption. Therefore, it is expected that the F-substituted CHAPs will be feasible as a F-releasing material for promoting bone formation
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/50/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.309-311.141.pdf
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