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  • 1
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    In:  Pageoph, Hokkaido University, Inst. f. Geophys., Ruhr-Univ. Bochum, vol. 154, no. 1, pp. 467-483, pp. 8038, (ISSN: 1340-4202)
    Publication Date: 1999
    Keywords: Source parameters ; Tsunami(s) ; Subduction zone ; Seismicity ; PAG
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  • 2
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    In:  Geophys. Res. Lett., Kunming, China, AGU, vol. 26, no. 22, pp. 3393-3396, pp. 2211, (ISSN: 1340-4202)
    Publication Date: 1999
    Keywords: Tsunami(s) ; Earthquake ; GRL ; 4564 ; Oceanography: ; physical ; Tsunamis ; and ; storm ; surges ; 7215 ; Seismology ; Earthquake ; parameters ; 7230 ; Seismicity ; and ; seismotectonics
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  • 3
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    In:  Geophys. Res. Lett., Kunming, China, AGU, vol. 23, no. 34, pp. 1549-1552, pp. 2211, (ISSN: 1340-4202)
    Publication Date: 1996
    Keywords: Source parameters ; Fault plane solution, focal mechanism ; Earthquake ; Modelling ; Tsunami(s) ; Japan ; GRL ; SRICHWALSKI
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  • 4
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    In:  Eos, Trans., Am. Geophys. Un., Kunming, China, AGU, vol. 74, no. 34, pp. 377, pp. 2211, (ISSN: 1340-4202)
    Publication Date: 1993
    Keywords: Earthquake ; Source
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  • 5
    Publication Date: 2009-05-30
    Description: The common marmoset (Callithrix jacchus) is increasingly attractive for use as a non-human primate animal model in biomedical research. It has a relatively high reproduction rate for a primate, making it potentially suitable for transgenic modification. Although several attempts have been made to produce non-human transgenic primates, transgene expression in the somatic tissues of live infants has not been demonstrated by objective analyses such as polymerase chain reaction with reverse transcription or western blots. Here we show that the injection of a self-inactivating lentiviral vector in sucrose solution into marmoset embryos results in transgenic common marmosets that expressed the transgene in several organs. Notably, we achieved germline transmission of the transgene, and the transgenic offspring developed normally. The successful creation of transgenic marmosets provides a new animal model for human disease that has the great advantage of a close genetic relationship with humans. This model will be valuable to many fields of biomedical research.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sasaki, Erika -- Suemizu, Hiroshi -- Shimada, Akiko -- Hanazawa, Kisaburo -- Oiwa, Ryo -- Kamioka, Michiko -- Tomioka, Ikuo -- Sotomaru, Yusuke -- Hirakawa, Reiko -- Eto, Tomoo -- Shiozawa, Seiji -- Maeda, Takuji -- Ito, Mamoru -- Ito, Ryoji -- Kito, Chika -- Yagihashi, Chie -- Kawai, Kenji -- Miyoshi, Hiroyuki -- Tanioka, Yoshikuni -- Tamaoki, Norikazu -- Habu, Sonoko -- Okano, Hideyuki -- Nomura, Tatsuji -- England -- Nature. 2009 May 28;459(7246):523-7. doi: 10.1038/nature08090.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Central Institute for Experimental Animals, 1430 Nogawa, Miyamae-ku, Kawasaki, Kanagawa 216-0001, Japan. esasaki@ciea.or.jp〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19478777" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Genetically Modified/*genetics ; Animals, Newborn ; Callithrix/embryology/*genetics ; *Disease Models, Animal ; Gene Expression Profiling ; Germ Cells/*metabolism ; Green Fluorescent Proteins/genetics ; Heredity/*genetics ; Humans ; Transcription, Genetic ; Transgenes/*genetics
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 154 (1999), S. 467-483 
    ISSN: 1420-9136
    Keywords: Key words: Tsunami, subduction zones, interplate earthquakes, intraplate earthquakes, tsunami earthquakes.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract —We classified tsunamigenic earthquakes in subduction zones into three types earth quakes at the plate interface (typical interplate events), earthquakes at the outer rise, within the subducting slab or overlying crust (intraplate events), and "tsunami earthquakes" that generate considerably larger tsunamis than expected from seismic waves. The depth range of a typical interplate earthquake source is 10–40km, controlled by temperature and other geological parameters. The slip distribution varies both with depth and along-strike. Recent examples show very different temporal change of slip distribution in the Aleutians and the Japan trench. The tsunamigenic coseismic slip of the 1957 Aleutian earthquake was concentrated on an asperity located in the western half of an aftershock zone 1200km long. This asperity ruptured again in the 1986 Andreanof Islands and 1996 Delarof Islands earthquakes. By contrast, the source of the 1994 Sanriku-oki earthquake corresponds to the low slip region of the previous interplate event, the 1968 Tokachi-oki earthquake. Tsunamis from intraplate earthquakes within the subducting slab can be at least as large as those from interplate earthquakes; tsunami hazard assessments must include such events. Similarity in macroseismic data from two southern Kuril earthquakes illustrates difficulty in distinguishing interplate and slab events on the basis of historical data such as felt reports and tsunami heights. Most moment release of tsunami earthquakes occurs in a narrow region near the trench, and the concentrated slip is responsible for the large tsunami. Numerical modeling of the 1996 Peru earthquake confirms this model, which has been proposed for other tsunami earthquakes, including 1896 Sanriku, 1946 Aleutian and 1992 Nicaragua.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 157 (2000), S. 977-988 
    ISSN: 1420-9136
    Keywords: Key Words: The 1994 Kuril tsunami, tsunami generation, numerical simulation.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract —The 1994 great Kuril earthquake generated an unusual tsunami that was observed at five tide gauges on the Hokkaido coast of the Okhotsk Sea. The tsunami arrived at tide gauges considerably earlier than the expected time, calculated on the assumption that the tsunami source area coincides with the aftershock area. Numerical simulation of the tsunami shows that the first wave of the tsunami in the Okhotsk Sea was generated by the significant subsidence north of the Kuril Islands. It is assumed that this subsidence is due to the earthquake. The coseismic deformation area of the ocean bottom extended over a vastly larger area than the aftershock area or the rupture area for the Kuril earthquake. The numerical simulation also shows that the tsunami observed at Utoro during the first hour after the origin time of the earthquake was mainly generated by the horizontal movement of the sloping ocean bottom near the Shiretoko Peninsula.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1211
    Keywords: Key words MHC class II ; Generation of diversity ; SLA-DRB1 ; SLA-DQB ; Sequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  The loci encoding the β chain of the pig major histocompatibility complex (MHC) class II antigens, SLA-DR and -DQ, have been known to exhibit a remarkable degree of allelic polymorphism. Here, to understand the generation of SLA class II polymorphism, 25 SLA-DRB1 and 24 SLA-DQB genes including newly identified 12 SLA-DRB1 and 7 SLA-DQB genes obtained from miniature pigs were analyzed based on the nucleotide and deduced amino acid sequences. Most of the allelic diversity was attributed to the variable sequences which encode a β1 domain consisting of a β-pleated sheet followed by an α helix. In the β1 domain coding region, there were four GC-rich sequences, which have been considered to involve the intra-exon sequence exchange also in other gene evolutions. The first and second GC-rich sequences were χ-like sequences, which have been shown to be a putative recombination signal, and were stably conserved among SLA-DRB1 and DQB genes. These χ-like sequences identified in SLA-DRB1 and SLA-DQB were found to encode the first turning point of the β-pleated sheet and the boundary between the β-pleated sheet and the α helix. Analysis of clustered sequence variation also suggested intra-exon gene conversions in which the χ-like sequences act as putative breakpoints. In addition to point mutations and selection mechanism, intra-exon gene conversions must be an important mechanism in the generation of allelic polymorphism at the SLA-DRB1 and SLA-DQB.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 114 (1983), S. 452-457 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 10
    Publication Date: 1987-01-01
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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