ISSN:
0009-2940
Keywords:
Enantioselectivity
;
Diels-Alder reactions
;
Spiro-β1-lactones
;
Retro cleavage
;
Resolution, topological
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The racemic β1-isopropyl-α1-methylene-β1-lactone 1 undergoes a configuration-dependent, highly selective [4 + 2] cycloaddition to the enantiomerically pure cyclopentadiene 2; chromatographic separation of the adducts and subsequent thermal retro cleavage provide the pure enantiomers (S)-1 and (R)-1 in 99% e.e.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19931260638
Permalink