Publication Date:
2018-10-30
Description:
Candida albicans gains azole resistance by altering sphingolipid composition 〈i〉Candida albicans〈/i〉 gains azole resistance by altering sphingolipid composition, Published online: 29 October 2018; doi:10.1038/s41467-018-06944-1 The fungal pathogen Candida albicans is diploid, which hinders genome-wide studies. Here, Gao et al. present a piggyBac transposon-mediated mutagenesis system using stable haploid C. albicans strains, and use it to identify genes and mechanisms underlying azole resistance.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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