ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Based on the molecular recognition theory, an organic molecules model was designed toinduce the hydroxyapatite crystallization, to build a tooth-like calcium phosphate/hydroxyapatiteunder a controllable way in vitro. The cross-linking of collagen on the dentin surface and gelatin wasoptimized by varying the molar ratio of N,N-(3-dimethylaminopropyl)- N'-ethyl-carbodiimidehydrochloride (EDC) and N-hydroxysuccinimide (NHS) at a constant EDC concentration. CaCl2 andNa3PO4-12H2O solutions were added after the crosslinking process. The whole process requiresrepeating the crosslinking and mineralization process for five times. The obtained composite werecharacterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM) as well as energydispersive X-ray photoelectron spectroscopy (XPS). The results showed that the dentinal tubule wereblocked by neonatal hydroxyapatite layer which has a continuous structure of columns crystal withsize of 10-40nm. Furthermore, there was column crystal with parallel direction inside, similar to thecrystal array in the top of enamel rod. This study showed that the specific organic molecule model canbe used as a potential effective crystal growth modifier
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.663.pdf
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