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  • 1
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    Low-energy theorems for nucleon-nucleon scattering at M_{π} =450 MeV (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-07-12
    Description: Author(s): V. Baru, E. Epelbaum, and A. A. Filin We apply the low-energy theorems to analyze the recent lattice QCD results for the two-nucleon system at a pion mass of M π ≃ 450 MeV obtained by the NPLQCD Collaboration. We find that the binding energies of the deuteron and dineutron are inconsistent with the low-energy behavior of the corresponding … [Phys. Rev. C 94, 014001] Published Mon Jul 11, 2016
    Keywords: Nucleon-Nucleon Interaction, Few-Body Systems
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 2
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    Remarks on study of X(3872) from effective field theory with pion-exchange interaction (2015)
    American Physical Society (APS)
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    Publication Date: 2015-02-03
    Description: Author(s): V. Baru, E. Epelbaum, A. A. Filin, F.-K. Guo, H.-W. Hammer, C. Hanhart, U.-G. Meißner, and A. V. Nefediev In a recent paper [P. Wang and X.-G. Wang, Phys. Rev. Lett. 111 , 042002 (2013)], the charmonium state X(3872) is studied in the framework of an effective field theory. In that work it is claimed that (i) the one-pion exchange (OPE) alone provides sufficient binding to produce the X as a shallow boun... [Phys. Rev. D 91, 034002] Published Mon Feb 02, 2015
    Keywords: Strong Interactions
    Print ISSN: 0556-2821
    Electronic ISSN: 1089-4918
    Topics: Physics
    Published by American Physical Society (APS)
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  • 3
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    Low-energy theorems for nucleon-nucleon scattering at unphysical pion masses (2015)
    American Physical Society (APS)
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    Publication Date: 2015-07-08
    Description: Author(s): V. Baru, E. Epelbaum, A. A. Filin, and J. Gegelia The longest-range part of the nuclear force from the one-pion exchange governs the energy dependence of the scattering amplitude in the near-threshold region and imposes correlations between the coefficients in the effective range expansion. These correlations may be regarded as low-energy theorems … [Phys. Rev. C 92, 014001] Published Tue Jul 07, 2015
    Keywords: Nucleon-Nucleon Interaction, Few-Body Systems
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 4
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    Binding energy of the X(3872) at unphysical pion masses (2015)
    American Physical Society (APS)
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    Publication Date: 2015-12-15
    Description: Author(s): V. Baru, E. Epelbaum, A. A. Filin, J. Gegelia, and A. V. Nefediev The chiral extrapolation of the X ( 3872 ) binding energy is investigated using the modified Weinberg formulation of chiral effective field theory for the D D ¯ * scattering. Given its explicit renormalizability, this approach is particularly useful to explore the interplay of the long- and short-range D D … [Phys. Rev. D 92, 114016] Published Fri Dec 11, 2015
    Keywords: Strong Interactions
    Print ISSN: 0556-2821
    Electronic ISSN: 1089-4918
    Topics: Physics
    Published by American Physical Society (APS)
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  • 5
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    Pion production in nucleon-nucleon collisions in chiral effective field theory: Next-to-next-to-leading order contributions (2012)
    American Physical Society (APS)
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    Publication Date: 2012-05-02
    Description: Author(s): A. A. Filin, V. Baru, E. Epelbaum, H. Krebs, C. Hanhart, A. E. Kudryavtsev, and F. Myhrer A complete calculation of the pion-nucleon loops that contribute to the transition operator for N N → N N π up-to-and-including next-to-next-to-leading order (N 2 LO) in chiral effective field theory near threshold is presented. The evaluation is based on the so-called momentum counting scheme, which takes... [Phys. Rev. C 85, 054001] Published Tue May 01, 2012
    Keywords: Nucleon-Nucleon Interaction, Few-Body Systems
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 6
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    Three-body DD[over ¯]π dynamics for the X(3872) (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-10-21
    Description: Author(s): V. Baru, A. A. Filin, C. Hanhart, Yu. S. Kalashnikova, A. E. Kudryavtsev, and A. V. Nefediev [Phys. Rev. D 84, 074029] Published Thu Oct 20, 2011
    Keywords: Strong interactions & Lattice methods
    Print ISSN: 0556-2821
    Electronic ISSN: 1089-4918
    Topics: Physics
    Published by American Physical Society (APS)
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  • 7
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    Pion production in nucleon-nucleon collisions in chiral effective field theory with Δ(1232) degrees of freedom (2013)
    American Physical Society (APS)
    Details
    Publication Date: 2013-12-13
    Description: Author(s): A. A. Filin, V. Baru, E. Epelbaum, H. Krebs, C. Hanhart, and F. Myhrer A calculation of the pion-production operator up to next-to-next-to-leading order for s -wave pions is performed within chiral effective field theory. In the previous study [ Phys. Rev. C 85 054001 (2012) ] we discussed the contribution of the pion-nucleon loops at the same order. Here we extend that... [Phys. Rev. C 88, 064003] Published Thu Dec 12, 2013
    Keywords: Nucleon-Nucleon Interaction, Few-Body Systems
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 8
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    Line shapes of the ${Z}_{b}(10610)$ and ${Z}_{b}(10650)$ in the elastic and inelastic channels revisited (2018)
    American Physical Society (APS)
    Details
    Publication Date: 2018-10-25
    Description: Author(s): Q. Wang, V. Baru, A. A. Filin, C. Hanhart, A. V. Nefediev, and J.-L. Wynen The most recent experimental data for all measured production and decay channels of the bottomoniumlike states Z b ( 10610 ) and Z b ( 10650 ) are analyzed simultaneously using solutions of the Lippmann-Schwinger equations which respect constraints from unitarity and analyticity. The interaction potential i... [Phys. Rev. D 98, 074023] Published Wed Oct 24, 2018
    Keywords: Strong Interactions
    Print ISSN: 0556-2821
    Electronic ISSN: 1089-4918
    Topics: Physics
    Published by American Physical Society (APS)
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  • 9
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    Functional links between Abeta toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast (2011)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2011-10-29
    Description: Abeta (beta-amyloid peptide) is an important contributor to Alzheimer's disease (AD). We modeled Abeta toxicity in yeast by directing the peptide to the secretory pathway. A genome-wide screen for toxicity modifiers identified the yeast homolog of phosphatidylinositol binding clathrin assembly protein (PICALM) and other endocytic factors connected to AD whose relationship to Abeta was previously unknown. The factors identified in yeast modified Abeta toxicity in glutamatergic neurons of Caenorhabditis elegans and in primary rat cortical neurons. In yeast, Abeta impaired the endocytic trafficking of a plasma membrane receptor, which was ameliorated by endocytic pathway factors identified in the yeast screen. Thus, links between Abeta, endocytosis, and human AD risk factors can be ascertained with yeast as a model system.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281757/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281757/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Treusch, Sebastian -- Hamamichi, Shusei -- Goodman, Jessica L -- Matlack, Kent E S -- Chung, Chee Yeun -- Baru, Valeriya -- Shulman, Joshua M -- Parrado, Antonio -- Bevis, Brooke J -- Valastyan, Julie S -- Han, Haesun -- Lindhagen-Persson, Malin -- Reiman, Eric M -- Evans, Denis A -- Bennett, David A -- Olofsson, Anders -- DeJager, Philip L -- Tanzi, Rudolph E -- Caldwell, Kim A -- Caldwell, Guy A -- Lindquist, Susan -- F32 NS067782-02/NS/NINDS NIH HHS/ -- K08 AG034290/AG/NIA NIH HHS/ -- K08AG034290/AG/NIA NIH HHS/ -- P30 AG019610/AG/NIA NIH HHS/ -- P30AG10161/AG/NIA NIH HHS/ -- R01 AG015819/AG/NIA NIH HHS/ -- R01 AG017917/AG/NIA NIH HHS/ -- R01AG15819/AG/NIA NIH HHS/ -- R01AG17917/AG/NIA NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2011 Dec 2;334(6060):1241-5. doi: 10.1126/science.1213210. Epub 2011 Oct 27.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22033521" target="_blank"〉PubMed〈/a〉
    Keywords: Alzheimer Disease/*genetics/*metabolism ; Amyloid beta-Peptides/chemistry/genetics/*metabolism ; Animals ; Animals, Genetically Modified ; Caenorhabditis elegans/cytology/genetics/metabolism ; Cell Membrane/metabolism ; Cells, Cultured ; Clathrin/metabolism ; Cytoskeleton/metabolism ; Disease Susceptibility ; *Endocytosis ; Genetic Association Studies ; Genetic Testing ; Glutamates/metabolism ; Humans ; Monomeric Clathrin Assembly Proteins/genetics/metabolism ; Neurons/physiology ; Peptide Fragments/chemistry/genetics/*metabolism ; Protein Multimerization ; Protein Transport ; Rats ; Risk Factors ; *Saccharomyces cerevisiae/cytology/genetics/growth & development/metabolism ; Saccharomyces cerevisiae Proteins/genetics/metabolism ; Secretory Pathway
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 10
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    Identification and rescue of alpha-synuclein toxicity in Parkinson patient-derived neurons (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-10-26
    Description: The induced pluripotent stem (iPS) cell field holds promise for in vitro disease modeling. However, identifying innate cellular pathologies, particularly for age-related neurodegenerative diseases, has been challenging. Here, we exploited mutation correction of iPS cells and conserved proteotoxic mechanisms from yeast to humans to discover and reverse phenotypic responses to alpha-synuclein (alphasyn), a key protein involved in Parkinson's disease (PD). We generated cortical neurons from iPS cells of patients harboring alphasyn mutations, who are at high risk of developing PD dementia. Genetic modifiers from unbiased screens in a yeast model of alphasyn toxicity led to identification of early pathogenic phenotypes in patient neurons. These included nitrosative stress, accumulation of endoplasmic reticulum (ER)-associated degradation substrates, and ER stress. A small molecule identified in a yeast screen (NAB2), and the ubiquitin ligase Nedd4 it affects, reversed pathologic phenotypes in these neurons.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022187/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022187/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chung, Chee Yeun -- Khurana, Vikram -- Auluck, Pavan K -- Tardiff, Daniel F -- Mazzulli, Joseph R -- Soldner, Frank -- Baru, Valeriya -- Lou, Yali -- Freyzon, Yelena -- Cho, Sukhee -- Mungenast, Alison E -- Muffat, Julien -- Mitalipova, Maisam -- Pluth, Michael D -- Jui, Nathan T -- Schule, Birgitt -- Lippard, Stephen J -- Tsai, Li-Huei -- Krainc, Dimitri -- Buchwald, Stephen L -- Jaenisch, Rudolf -- Lindquist, Susan -- 5 R01CA084198/CA/NCI NIH HHS/ -- K01 AG038546/AG/NIA NIH HHS/ -- P50 AG005134/AG/NIA NIH HHS/ -- R01 CA084198/CA/NCI NIH HHS/ -- R01 GM058160/GM/NIGMS NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2013 Nov 22;342(6161):983-7. doi: 10.1126/science.1245296. Epub 2013 Oct 24.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24158904" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Benzimidazoles/chemistry/*pharmacology ; Endoplasmic Reticulum Stress/drug effects ; Female ; Humans ; Induced Pluripotent Stem Cells/cytology/metabolism ; Mutation ; Neurogenesis ; Neurons/*drug effects/metabolism/pathology ; Parkinson Disease/genetics/*metabolism ; Rats ; alpha-Synuclein/genetics/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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