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  • 1
    Electronic Resource
    Electronic Resource
    Sex-related changes in the bone mineral content of atrophic mandibles (1994)
    Springer
    Calcified tissue international 54 (1994), S. 203-207 
    Details
    ISSN: 1432-0827
    Keywords: Mandible ; Atrophy ; Bone mineral content
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract In 25 edentulous anatomical mandible specimens (15 female, age range 69–90 years; 10 male, age range 68–88 years), the bone mineral content (BMC) was measured by dual-photon absorptiometry (DPA) and analyzed in a standardized area of the mandibular body. The results of our BMC examinations showed that there was a significant difference (P=0.05) between the two sexes. Another notable fact was that, with advancing age, the values measured in the male mandibles tended to increase slightly but in a statistically significant way. Those of the female mandibles tended to decrease with age. A possible explanation for this observation may be derived from the fact that a reduction of the mandibular height leads to a reduction of the moment of resistance. As functional adaptation in order to preserve the stability of the atrophic body of the mandible, the amount of inner cortical bone of the male mandibles increases, leading to a reduction of the cancellous portion. In the mandibles of women, postmenopausal osteoporosis seems to prevent an analogous compensation mechanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00301679
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    Paper (German National Licenses)
    Fulltext
  • 2
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    Coherent Control of Electron-LO-Phonon Scattering in Bulk GaAs (1998)
    American Physical Society
    Details
    Publication Date: 1998-03-02
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
    Published by American Physical Society
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    PAPER CURRENT
  • 3
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    Experiment K-7-29: Connective Tissue Studies (1994)
    In:  CASI
    Details
    Publication Date: 2004-12-03
    Description: The skin repair studies started to be problematic for the following reasons: (1) It was very difficult to locate the wound and many lesions were not of the same dimensions. A considerable amount of time was devoted to the identification of the wound using polarized light. We understand that this experiment was added on to the overall project. Marking of the wound site and standard dimensions should be recommended for the next flight experiment. (2) The tissue was frozen, therefore thawing and fixation caused problems with some of the immunocytochemical staining for obtaining better special resolution with light microscopy image processing. Despite these problems, we were unable to detect any significant qualitative differences for the following wound markers: (1) Collagen Type 3, (2) Hematotoxylin and Eosin, and (3) Macrophage Factor 13. All protein markers were isolated from rat sources and antibodies prepared and tested for cross reactivity with other molecules at the University of Wisconsin Hybridoma Facility. However, rat skin from the non lesioned site 'normal' showed interesting biochemical results. Skin was prepared for the following measurements: (1) DNA content, (2) Collagen content by hydroxyproline, and (3) uronic acid content and estimation of ground substance. The results indicated there was a non-significant increase (10%) in the DNA concentration of skin from flight animals. However, the data expressed as a ratio DNA/Collagen estimates the cell or nuclear density that supports a given quantity of collagen showed a dramatic increase in the flight group (33%). This means flight conditions may have slowed down collagen secretion and/or increased cell proliferation in adult rat skin. Further biochemical tests are being done to determine the crosslinking of elastin which will enhance the insight to assessing changes in skin turnover.
    Keywords: Life Sciences (General)
    Type: US Experiments Flown on the Soviet Biosatellite Cosmos 2044; 233-238; NASA-TM-108802
    Format: text
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    NASA TECHNICAL REPORTS
  • 4
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    Adaptations of young adult rat cortical bone to 14 days of spaceflight (1992)
    In:  Other Sources
    Details
    Publication Date: 2019-08-28
    Description: To determine whether mature humeral cortical bone would be modified significantly by an acute exposure to weightlessness, adult rats (110 days old) were subjected to 14 days of microgravity on the COSMOS 2044 biosatellite. There were no significant changes in peak force, stiffness, energy to failure, and displacement at failure in the flight rats compared with ground-based controls. Concentrations and contents of hydroxyproline, calcium, and mature stable hydroxylysylpyridinoline and lysylpyridinoline collagen cross-links remained unchanged after spaceflight. Bone lengths, cortical and endosteal areas, and regionl thicknesses showed no significant differences between flight animals and ground controls. The findings suggest that responsiveness of cortical bone to microgravity is less pronounced in adult rats than in previous spaceflight experiments in which young growing animals were used. It is hypothesized that 14 days of spaceflight may not be sufficient to impact the biochemical and biomechanical properties of cortical bone in the mature rat skeleton.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Journal of Applied Physiology, Supplement (ISSN 8750-7587); 73; 2 Au
    Format: text
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    NASA TECHNICAL REPORTS
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