ISSN:
0170-2041
Keywords:
Ca++-ATPase activator
;
Ceramides
;
Marine natural products
;
Sphingosines
;
Symbioramide
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Symbioramide [(2S,2′R,3R, 3′E)-N-(2′-hydroxy-3′-octadecenoyl)dihydrosphingosine, 1] was synthesized from D-erythro-dihydrosphingosine (19) and (R, E)-2′-tert-butyldimethylsilyloxy-3′-octadecenoic acid (14), which was prepared from (E)-2-octadecen-1-ol (4) by employing the Sharpless asymmetric epoxidation. The (2S,2′S,3R,3′E)-isomer 28 of 1 was also synthesized to further confirm the structure of 1.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199419940109
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