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  • 1
    Publication Date: 2011-08-24
    Description: Circadian rhythms of activity (Act) and body temperature (Tb) were recorded from male Syrian hamsters under square-wave (LDSq) and simulated natural (LDSN, with dawn and dusk transitions) light-dark cycles. Light intensity and data sampling were under the synchronized control of a laboratory computer. Changes in reactive and predictive onsets and offsets for the circadian rhythms of Act and Tb were examined in both lighting conditions. The reactive Act onset occurred 1.1 h earlier (P 〈 0.01) in LDSN than in LDSq and had a longer alpha-period (1.7 h; P 〈 0.05). The reactive Tb onset was 0.7 h earlier (P 〈 0.01) in LDSN. In LDSN, the predictive Act onset advanced by 0.3 h (P 〈 0.05), whereas the Tb predictive onset remained the same as in LDSq. The phase angle difference between Act and Tb predictive onsets decreased by 0.9 h (P 〈 0.05) in LDSN, but the offsets of both measures remained unchanged. In this study, animals exhibited different circadian entrainment characteristics under LDSq and LDSN, suggesting that gradual and abrupt transitions between light and dark may provide different temporal cues.
    Keywords: Life Sciences (General)
    Type: The American journal of physiology (ISSN 0002-9513); Volume 276; 4 Pt 2; R1195-202
    Format: text
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  • 2
    Publication Date: 2019-08-16
    Description: Researchers examined the effect of late prenatal exposure to microgravity on the development of the retina, retinohypothalamic tract, geniculo-hypothalamic tract, and suprachiasmatic nucleus. Results indicate an effect on c-fos activity in the intergeniculate leaflet between gestational day 20 and postnatal day 8, suggesting a delay in development of the circadian timing system.
    Keywords: Life Sciences (General)
    Type: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology (ISSN 1077-9248); 4; 2; P67-70
    Format: text
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  • 3
    Publication Date: 2019-07-13
    Description: The static gravitational field of the earth has been an important selective pressure that has shaped the evolution of biological organisms. This is illustrated by the evolution of tetrapods from a water environment where gravitational force was partially negated to a terrestrial environment where gravity is of greater consequence. Terrestrial invasion resulted in a series of new structural, physiological, and behavioral features. Therefore, it is not surprising that alterations in the gravitational field can cause widespread effects in many physiological systems and behaviors. Our previous studies have demonstrated that both exposure to hyperdynamic fields and the microgravity condition of space flight have significant effects on body temperature, heartrate, activity, feeding, drinking, and circadian rhythms. However, it has not been determined whether these physiological adaptations are associated with changes in neural activity within the hypothalamic nuclei that regulate these functions. This study examined the changes in body temperature, activity, body weight and food and water intake in rats caused by exposure to a hyperdynamic field. In addition, the immediate early gene activation marker, c-Fos, was used to examine potential protein synthesis changes in the hypothalamic nuclei that regulate these functions.
    Keywords: Aerospace Medicine
    Type: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology (ISSN 1077-9248); 1; 1; P69-70
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