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  • 1
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    Tomographic Reconstruction of Two-Dimensional Residual Strain Fields from Bragg-Edge Neutron Imaging (2018)
    American Physical Society (APS)
    Details
    Publication Date: 2018-12-14
    Description: Author(s): A.W.T. Gregg, J.N. Hendriks, C.M. Wensrich, A. Wills, A.S. Tremsin, V. Luzin, T. Shinohara, O. Kirstein, M.H. Meylan, and E.H. Kisi Residual stress arising from many manufacturing processes ( e . g . welding, forming, or additive manufacturing) can have a profound effect on mechanical performance. Strain tomography via neutron imaging promises a powerful experimental approach, but has been demonstrated in just a small number of special cases. The authors develop a general algorithm for tomographic reconstruction of residual strain fields in two dimensions, and experimentally demonstrate the technique. Strain tomography has the potential to impact a number of fields within experimental mechanics, and this study represents a significant step toward the ultimate goal: general reconstruction in three dimensions. [Phys. Rev. Applied 10, 064034] Published Thu Dec 13, 2018
    Electronic ISSN: 2331-7019
    Topics: Physics
    Published by American Physical Society (APS)
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  • 2
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    Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-kappa B (1992)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1992-12-11
    Description: Mice transgenic for the human T cell leukemia virus (HTLV-I) Tax gene develop fibroblastic tumors that express NF-kappa B-inducible early genes. In vitro inhibition of NF-kappa B expression by antisense oligodeoxynucleotides (ODNs) inhibited growth of these culture-adapted Tax-transformed fibroblasts as well as an HTLV-I-transformed human lymphocyte line. In contrast, antisense inhibition of Tax itself had no apparent effect on cell growth. Mice treated with antisense to NF-kappa B ODNs showed rapid regression of transplanted fibrosarcomas. This suggests that NF-kappa B expression may be necessary for the maintenance of the malignant phenotype and provides a therapeutic approach for HTLV-I-associated disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kitajima, I -- Shinohara, T -- Bilakovics, J -- Brown, D A -- Xu, X -- Nerenberg, M -- CA50234/CA/NCI NIH HHS/ -- MH47680/MH/NIMH NIH HHS/ -- NS01330/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1992 Dec 11;258(5089):1792-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1299224" target="_blank"〉PubMed〈/a〉
    Keywords: 3T3 Cells ; Animals ; Base Sequence ; Cell Division/drug effects ; Cell Line ; Cell Transformation, Neoplastic ; Fibrosarcoma/*drug therapy/pathology ; *Genes, pX ; Human T-lymphotropic virus 1/*genetics ; Humans ; Kinetics ; Lymphocytes ; Mice ; Mice, Transgenic ; Molecular Sequence Data ; NF-kappa B/*antagonists & inhibitors/genetics ; Oligodeoxyribonucleotides ; Oligonucleotides, Antisense/*pharmacology/*therapeutic use
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    High-resolution gravity measurement aboard an autonomous underwater vehicle (2018)
    Society of Exploration Geophysicists (SEG)
    Details
    Publication Date: 2018
    Description: 〈span〉〈div〉ABSTRACT〈/div〉We have developed an underwater gravity measurement system that uses an autonomous underwater vehicle (AUV) for exploration of seafloor mineral deposits. An improved air/sea gravimeter mounted on a gimbal mechanism in a pressure capsule 50 cm in diameter was installed in the AUV 〈span〉Urashima〈/span〉. We carried out 11 AUV dives in Sagami Bay as well as in deep-sea mineral deposit areas offshore Japan. The AUV was navigated at a constant speed of 2 knots and at either constant depth or constant altitude above the sea bottom. We obtained high-resolution Bouguer anomaly data through processing of gravity data, water pressure data, and the AUV’s navigational data, including pitch and roll motion. In addition to a vertical acceleration correction using a precise pressure meter with an in situ conversion factor from pressure to depth, three additional corrections were made to the gravimeter data: corrections for the effects of a spatial separation and a time delay between the depth sensor and the gravimeter, and an adjustment to the conversion from pressure increments to depth increments. These new corrections allowed us to obtain high-resolution data in a constant-depth survey of the southern Izena Hole at a depth of approximately 1550 m. The data had a 0.1 mGal rms crossover difference after leveling. This survey revealed two high Bouguer anomaly areas with amplitudes of 1–2 mGal. A model calculation suggested that the anomalies result from the presence of two buried cylindrical high-density mineral deposits. Our data processing method allows the detection of mineral deposits located at or just beneath the seafloor using gravity data collected aboard AUVs. However, further improvements in resolution are desirable, particularly for surveys in areas with rugged topography.〈/span〉
    Print ISSN: 0016-8033
    Electronic ISSN: 1942-2156
    Topics: Geosciences , Physics
    Published by Society of Exploration Geophysicists (SEG)
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  • 4
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    Ablation of transplanted HTLV-I tax-transformed tumors in mice by antisense inhibition of NF-kappa B (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-03-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kitajima, I -- Shinohara, T -- Bilakovics, J -- Brown, D A -- Xu, X -- Nerenberg, M -- New York, N.Y. -- Science. 1993 Mar 12;259(5101):1523.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8456277" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cell Transformation, Neoplastic ; *Genes, pX ; Human T-lymphotropic virus 1/*genetics ; Humans ; Mice ; Molecular Sequence Data ; Oligodeoxyribonucleotides ; Oligonucleotides, Antisense
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    alpha A-crystallin messenger RNA of the mouse lens: more noncoding than coding sequences (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-02-19
    Description: The 14S messenger RNA (1300 to 1500 nucleotides) for the alpha A chain of alpha-crystallin of the mammalian lens is nearly three times larger than required to code for the polypeptide that contains 173 amino acids. As a means of accounting for this anomaly, a complementary DNA clone for the mouse alpha A-crystallin messenger RNA was constructed in pBR322 and sequenced. Derivation of the protein sequence from the nucleic acid sequence showed that mouse alpha A-crystallin is similar to that of other organisms. The messenger RNA contains 536 nucleotides located on the 3' side of the coding region, excluding the polyadenylate stretch. This 3' sequence does not encode any other crystallin and has multiple termination codons in the three possible reading frames.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉King, C R -- Shinohara, T -- Piatigorsky, J -- New York, N.Y. -- Science. 1982 Feb 19;215(4535):985-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7156978" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Cloning, Molecular ; Crystallins/*genetics ; Mice ; RNA, Messenger/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Linked dimensions of psychopathology and connectivity in functional brain networks (2018)
    Springer Nature
    Details
    Publication Date: 2018-08-02
    Description: Linked dimensions of psychopathology and connectivity in functional brain networks Linked dimensions of psychopathology and connectivity in functional brain networks, Published online: 01 August 2018; doi:10.1038/s41467-018-05317-y Co-morbidity and symptom overlap make it difficult to associate psychiatric disorders with unique neural signatures. Here, the authors use a data-driven approach to show that the symptom dimensions of mood, psychosis, fear and externalizing behavior exhibit unique patterns of functional dysconnectivity.
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
    Published by Springer Nature
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  • 7
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    Persistence of crystallin messenger RNA's with reduced translation in hereditary cataracts in mice (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-21
    Description: In vitro translation experiments showed that the lens fiber cells of two hereditary cataracts in mice (Nakano and Philly) possessed a full complement of crystallin messenger RNA's, despite severely reduced synthesis of crystallin in these cells. The reduction in synthesis in the lens fiber cells correlated with the increase in Na+ and the decrease in K+, which occurs during cataractogenesis. In contrast to the fiber cells, the epithelial cells continued to synthesize crystallins in the cataractous lenses. Crystallin synthesis was stimulated in the fiber cells by raising the K+ concentration and lowering the Na+ concentration in the cultured lenses. The reduction in crystallin synthesis in the initial stages of cataractogenesis in the Nakano and Philly lenses thus appears to be due to poor utilization of crystallin messenger RNA's in the fiber cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shinohara, T -- Piatigorsky, J -- New York, N.Y. -- Science. 1980 Nov 21;210(4472):914-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434006" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cataract/genetics/*metabolism ; Crystallins/biosynthesis/*genetics ; Disease Models, Animal ; Mice ; Mice, Mutant Strains/metabolism ; Potassium/metabolism ; Protein Biosynthesis ; RNA, Messenger/*metabolism ; Sodium/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Selective loss of a family of gene transcripts in a hereditary murine cataract (1985)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1985-01-04
    Description: The eye lens of the Fraser mouse contains a dominantly inherited cataract with reduced amounts of seven distinct but homologous gamma crystallins encoded by a family of gamma-crystallin genes. The results of experiments with cultured lenses, cell-free RNA translation, and Northern blot hybridization indicated a specific loss of the family of gamma-crystallin messenger RNA's in the Fraser mouse lens. Southern blot hybridization of genomic DNA's from normal and Fraser mice showed no differences in gamma-crystallin coding sequences.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Garber, A T -- Winkler, C -- Shinohara, T -- King, C R -- Inana, G -- Piatigorsky, J -- Gold, R J -- New York, N.Y. -- Science. 1985 Jan 4;227(4682):74-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3964960" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cataract/*genetics ; Crystallins/*genetics ; Genes ; Lens, Crystalline/metabolism ; Mice ; Mice, Mutant Strains ; Nucleic Acid Hybridization ; Protein Biosynthesis ; RNA, Messenger/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    Far-field interference of a neutron white beam and the applications to noninvasive phase-contrast imaging (2017)
    American Physical Society (APS)
    Details
    Publication Date: 2017-04-27
    Description: Author(s): D. A. Pushin, D. Sarenac, D. S. Hussey, H. Miao, M. Arif, D. G. Cory, M. G. Huber, D. L. Jacobson, J. M. LaManna, J. D. Parker, T. Shinohara, W. Ueno, and H. Wen The phenomenon of interference plays a crucial role in the field of precision measurement science. Wave-particle duality has expanded the well-known interference effects of electromagnetic waves to massive particles. The majority of the wave-particle interference experiments require a near monochrom… [Phys. Rev. A 95, 043637] Published Wed Apr 26, 2017
    Keywords: Matter waves and collective properties of cold atoms and molecules
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
    Published by American Physical Society (APS)
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  • 10
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    Corrosion under heat flux encountered in desalination plant (1977)
    Elsevier
    Details
    Publication Date: 1977-12-01
    Print ISSN: 0011-9164
    Electronic ISSN: 1873-4464
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Process Engineering, Biotechnology, Nutrition Technology
    Published by Elsevier
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